Page last updated: 2024-08-21

pyrazines and Muscle Relaxation

pyrazines has been researched along with Muscle Relaxation in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (11.11)	18.7374
1990's	21 (58.33)	18.2507
2000's	9 (25.00)	29.6817
2010's	2 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Clozel, M; Gatfield, J; Gnerre, C; Hess, P; Iglarz, M; Menyhart, K; Monnier, L; Morrison, K; Nayler, O; Wanner, D	1
Chan, HC; Cui, YG; Gou, YL; Rowlands, DK; Wong, HY	1
Amin, K; Antonsson, M; Broddefalk, J; Jensen, J; Jin, S; Lehmann, A; Nilsson, K; Plowright, AT; St-Onge, S; Tomaszewski, MJ; Tremblay, M; Ulander, J; Walpole, C; Wei, Z; Yang, H	1
He, GW; Kwan, YW; Kwok, CC; Shan Au, AL; Zhang, RZ	1
Kim, B; Kim, EY; Rhyu, MR	1
Chen, J; Chen, Z; Fan, L; Liu, J; Wang, T; Xiao, H; Ye, Z; Yin, C	1
Chen, J; Fan, L; Liu, J; Wang, T; Xiao, H; Ye, Z; Yin, C	1
De Man, JG; De Schepper, HU; De Winter, BY; Deiteren, A; Herman, AG; Martinet, W; Pelckmans, PA; Ruyssers, NE; Timmermans, JP; Van Nassauw, L	1
Abou-Gharbia, M; Freed, ME; McCaully, RJ; Silver, PJ; Wendt, RL	1
Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A	1
Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A	2
Dent, G; Liebig, S; Magnussen, H; Rabe, KF; Schudt, C; Tenor, H	1
Chen, HM; Lin, CI; Tao, PL; Wei, J; Wu, SL	1
Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Hadj-Kaddour, K; Laurent, F; Michel, A	1
Chilvers, ER; Macmillan, S; Patmore, L; Sheridan, RD	1
Advenier, C; Bakdach, H; Bonnet, PA; Cui, YY; Michel, A; Naline, E	1
Berto, L; Bonnet, PA; Cortijo, J; Michel, A; Morcillo, EJ; Navarrete, C; Sanz, C; Villagrasa, V	1
Hucks, D; Kan, YM; Peng, W; Priest, RM; Ward, JP	1
Buchheit, KH; Hofmann, A; Pfannkuche, HJ	1
Fozard, JR; Müller-Schweinitzer, E	1
Eckly-Michel, AE; Le Bec, A; Lugnier, C	1
Eckly-Michel, A; Lugnier, C; Martin, V	1
Bonnet, PA; Chiu, P; Elliott, KR; Foster, RW; Isaac, LM; Laurent, F; Michel, A; Pocock, TM; Small, RC	1
Advenier, C; Cortijo, J; Dasí, F; Marín, N; Martinez-Losa, M; Morcillo, EJ; Pons, R	1
Adams, MA; Bennett, BM; Fraser, AB; Ratz, JD; Rees-Milton, KJ	1
Alkorta, I; Campillo, N; García, C; Goya, P; Páez, JA	1
Benezech, V; Bonnet, P; Chapat, J; Deleuze-Masquefa, C; Elliott, K; Escale, R; Fabreguettes, J; Laurent, F; Michel, A; Parra, S; Pocock, T; Small, R; Subra, G; Vidal, J	1
Anderson, WH; Fitzpatrick, DF; Hwang, DP; Krzanowski, JJ; Polson, JB; Szentivanyi, A	1
Archer, GA; Kalish, RI; Ning, RY; Sluboski, BC; Stempel, A; Steppe, TV; Sternbach, LH	1
Chen, MC; Daniel, EE; Kwan, CY	1
Hall, IP; Hill, SJ	1
Barnette, MS; Barone, FC; Fowler, PJ; Grous, M; Ormsbee, HS; Price, WJ	1
Barnes, PJ; Rhoden, KJ	1
Barnette, MS; Grous, M; Ormsbee, HS; Torphy, TJ	1
Chiou, WF; Wu, CC; Yen, MH	1

Other Studies

36 other study(ies) available for pyrazines and Muscle Relaxation

Article	Year
Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low The Journal of pharmacology and experimental therapeutics, 2017, Volume: 362, Issue:1 Topics: Acetamides; Acetates; Animals; beta-Arrestins; Cell Proliferation; CHO Cells; Contractile Proteins; Cricetinae; Cricetulus; Cyclic AMP; Epoprostenol; Extracellular Matrix; Humans; Hypertension, Pulmonary; Iloprost; Male; Muscle Contraction; Muscle Relaxation; Pyrazines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Epoprostenol	2017
Traditional Chinese medicine Bak Foong Pills alters uterine quiescence - possible role in alleviation of dysmenorrhoeal symptoms. Cell biology international, 2009, Volume: 33, Issue:12 Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Drugs, Chinese Herbal; Dysmenorrhea; Female; Fluorometry; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Muscle Relaxation; Myometrium; Pyrazines; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus	2009
Discovery of agonists of cannabinoid receptor 1 with restricted central nervous system penetration aimed for treatment of gastroesophageal reflux disease. Journal of medicinal chemistry, 2013, Jan-10, Volume: 56, Issue:1 Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Benzamides; Biological Availability; Brain; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; ERG1 Potassium Channel; Esophageal Sphincter, Lower; Ether-A-Go-Go Potassium Channels; Gastroesophageal Reflux; High-Throughput Screening Assays; Humans; Muscle Relaxation; Pyrazines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Solubility; Structure-Activity Relationship; Sulfoxides; Triazoles	2013
Mechanisms responsible for the in vitro relaxation of ligustrazine on porcine left anterior descending coronary artery. European journal of pharmacology, 2003, May-16, Volume: 468, Issue:3 Topics: Animals; Calcium; Calcium Channels, L-Type; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Pyrazines; Signal Transduction; Structure-Activity Relationship; Swine	2003
Nitric oxide-mediated vasorelaxation by Rhizoma Ligustici wallichii in isolated rat thoracic aorta. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:1 Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Ligusticum; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Phytotherapy; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents	2004
[Effect of chuanxiongzine on the relaxation of isolated rabbit corpus cavernosum tissues]. Zhonghua nan ke xue = National journal of andrology, 2004, Volume: 10, Issue:8 Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Penis; Pyrazines; Rabbits	2004
Effects of ligustrazine on the contraction of isolated rabbit corpus cavernosum strips. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:5 Topics: Animals; Calcium Channels; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Penis; Phenylephrine; Potassium Chloride; Pyrazines; Rabbits	2005
TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats. American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:1 Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Gastric Emptying; Gastrointestinal Motility; Gastroparesis; Intestinal Mucosa; Intestines; Male; Muscle Relaxation; Neurons, Afferent; Peptide Fragments; Pyrazines; Pyridines; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels	2008
Tetrahydropyrrolo[1,2-a]quinoxalines and tetrahydropyrrolo[1,2-a]pyrido[3,2-a]pyrazines: vascular smooth muscle relaxants and antihypertensive agents. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Chemical Phenomena; Chemistry; Female; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Optical Rotation; Pyrazines; Pyrroles; Quinoxalines; Rabbits; Spectrophotometry, Infrared; Structure-Activity Relationship	1984
[Effects of toxins, apamine, charybdotoxin and iberiotoxin on the relaxation of the smooth muscular fiber induced by imidazo(1,2-a)pyrazine derivative]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1993, Volume: 187, Issue:4 Topics: Animals; Apamin; Charybdotoxin; Guinea Pigs; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Peptides; Potassium Channels; Pyrazines; Scorpion Venoms; Trachea	1993
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis. British journal of pharmacology, 1993, Volume: 108, Issue:3 Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Potassium Channels; Potassium Chloride; Pyrazines; Scorpion Venoms; Trachea	1993
Phosphodiesterase isozymes modulating inherent tone in human airways: identification and characterization. The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adult; Aged; Bucladesine; Colforsin; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoenzymes; Lung; Lung Neoplasms; Male; Middle Aged; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nitroprusside; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rolipram; Vital Capacity	1993
The role of cyclic AMP and phosphodiesterase activity in the mechanism of action of tetramethylpyrazine on human and dog cardiac and dog coronary arterial tissues. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:11 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Animals; Coronary Vessels; Cyclic AMP; Dogs; Epinephrine; Female; Heart; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Purkinje Fibers; Pyrazines; Theophylline; Vasodilator Agents	1993
Cardiovascular effects of SCA40, a novel potassium channel opener, in rats. British journal of pharmacology, 1993, Volume: 110, Issue:3 Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Dose-Response Relationship, Drug; Drug Interactions; Heart Atria; Heart Rate; Imidazoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Parasympatholytics; Potassium Channels; Propranolol; Pyrazines; Rats; Rats, Wistar	1993
A comparison of the effects of SCA40, NS 004 and NS 1619 on large conductance Ca(2+)-activated K+ channels in bovine tracheal smooth muscle cells in culture. British journal of pharmacology, 1995, Volume: 116, Issue:1 Topics: Animals; Benzimidazoles; Calcium; Cattle; Cells, Cultured; Chlorophenols; Electric Conductivity; Imidazoles; In Vitro Techniques; Ion Channel Gating; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Potassium Channels; Pyrazines; Trachea	1995
Pharmacological activities of imidazo[1,2-alpha]pyrazine derivatives. Arzneimittel-Forschung, 1995, Volume: 45, Issue:12 Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Cattle; Diuresis; Guinea Pigs; Heart Atria; Heart Rate; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Phosphodiesterase Inhibitors; Pyrazines; Rabbits; Rats; Rats, Wistar; Theophylline; Trachea	1995
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim. Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4 Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Cromakalim; Electric Stimulation; Female; Glyburide; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Nitroprusside; Osmolar Concentration; Parasympatholytics; Potassium Channel Blockers; Potassium Channels; Pyrazines; Pyrroles; Tetraethylammonium; Tetraethylammonium Compounds	1996
Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim. British journal of pharmacology, 1996, Volume: 119, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Bronchi; Bronchodilator Agents; Calcium; Cardiotonic Agents; Cromakalim; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; Imidazoles; In Vitro Techniques; Leukocyte Elastase; Leukotriene B4; Muscle Relaxation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoric Diester Hydrolases; Pyrazines; Pyrroles; Pyrrolidinones; Rolipram; Superoxides	1996
Ligustrazine-induced endothelium-dependent relaxation in pulmonary arteries via an NO-mediated and exogenous L-arginine-dependent mechanism. British journal of pharmacology, 1996, Volume: 119, Issue:5 Topics: Animals; Arginine; Endothelium, Vascular; Male; Muscle Relaxation; Nitric Oxide; Pulmonary Artery; Pyrazines; Rats; Rats, Wistar; Vasodilator Agents	1996
In vitro and in vivo effects of SCA40 on guinea pig airways. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2 Topics: Albuterol; Animals; Blood Pressure; Bombesin; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Heart Rate; Histamine; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Pyrazines; Respiratory Hypersensitivity; Trachea	1997
SCA 40: studies of the relaxant effects on cryopreserved human airway and vascular smooth muscle. British journal of pharmacology, 1997, Volume: 120, Issue:7 Topics: Albuterol; Bronchi; Carbachol; Cryopreservation; Drug Interactions; Humans; Imidazoles; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Pyrazines	1997
Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases. European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1 Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Benzophenanthridines; Cardiotonic Agents; Cattle; Drug Interactions; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Glycoproteins; Hydrolysis; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Pyrazines; Rats; Rats, Wistar	1997
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation. British journal of pharmacology, 1997, Volume: 122, Issue:1 Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Signal Transduction; Sulfonamides; Thionucleotides	1997
Effects of SCA40 on bovine trachealis muscle and on cyclic nucleotide phosphodiesterases. European journal of pharmacology, 1997, Sep-03, Volume: 334, Issue:1 Topics: Animals; Bronchodilator Agents; Cattle; Cromakalim; Dose-Response Relationship, Drug; Electrophysiology; Glycoproteins; Imidazoles; Isoproterenol; Membrane Potentials; Muscle Relaxation; Parasympatholytics; Pyrazines; Rubidium; Trachea	1997
Bronchodilator and anti-inflammatory activities of SCA40: studies in human isolated bronchus, human eosinophils, and in the guinea-pig in vivo. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Bronchi; Bronchial Hyperreactivity; Bronchodilator Agents; Eosinophils; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Leukotriene C4; Muscle Relaxation; Muscle, Smooth; Pyrazines	1997
Endothelin receptor antagonism does not prevent the development of in vivo glyceryl trinitrate tolerance in the rat. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:2 Topics: Animals; Aorta, Thoracic; Binding, Competitive; Biotransformation; Blood Pressure; Cyclic GMP; Drug Tolerance; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitroglycerin; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sulfonamides; Vasodilator Agents	2000
Novel bronchodilators: synthesis, transamination reactions, and pharmacology of a series of pyrazino[2,3-c][1,2,6]thiadiazine 2, 2-dioxides. Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22 Topics: Animals; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Muscle Relaxation; Muscle, Smooth; Pyrazines; Rats; Structure-Activity Relationship; Thiadiazines; Toxicity Tests, Acute; Trachea	2000
Imidazo[1,2-a]quinoxalines: synthesis and cyclic nucleotide phosphodiesterase inhibitory activity. European journal of medicinal chemistry, 2001, Volume: 36, Issue:3 Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cardiotonic Agents; Cattle; Enzyme Inhibitors; Guinea Pigs; Inhibitory Concentration 50; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Muscle Relaxation; Muscle, Smooth; Nitriles; Pyrazines; Quinoxalines; Structure-Activity Relationship	2001
Analysis of the relationship between pharmacological inhibition of cyclic nucleotide phosphodiesterase and relaxation of canine tracheal smooth muscle. Biochemical pharmacology, 1979, Apr-15, Volume: 28, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Airway Resistance; Animals; Caffeine; Dogs; Etazolate; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Theophylline; Trachea; Triazoles	1979
Quinazolines and 1,4-benzodiazepines. 82.1 5-Pyrimidyl-and 5-pyrazinylbenzodiazepines. Journal of medicinal chemistry, 1977, Volume: 20, Issue:10 Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Cats; Electroshock; Humans; Mice; Muscle Relaxation; Pentylenetetrazole; Pyrazines; Pyrimidines	1977
Inhibition of vasoconstriction by tetramethylpyrazine: does it act by blocking the voltage-dependent Ca channel? Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1 Topics: Animals; Calcium; Dogs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Pyrazines; Vasoconstriction	1990
Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone. Biochemical pharmacology, 1992, Jan-09, Volume: 43, Issue:1 Topics: Animals; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Isoenzymes; Methacholine Chloride; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rolipram; Trachea	1992
Human lower oesophageal sphincter relaxation is associated with raised cyclic nucleotide content. Gut, 1991, Volume: 32, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Humans; In Vitro Techniques; Muscle Relaxation; Nitroprusside; Nucleotides, Cyclic; Purinones; Pyrazines; Tetrodotoxin	1991
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Potassium Chloride; Pyrazines; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide	1990
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Electric Stimulation; Enzyme Activation; Esophagogastric Junction; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Protein Kinases; Purinones; Pyrazines	1990
A possible mechanism of action of tetramethylpyrazine on vascular smooth muscle in rat aorta. European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3 Topics: Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Theophylline; Vasodilation	1989