Page last updated: 2024-08-21

pyrazines and Long QT Syndrome

pyrazines has been researched along with Long QT Syndrome in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Fenioux, C; Funck-Brentano, C; Gligorov, J; Gougis, P; Solas, C; Spano, JP; Veyri, M1
Ahmed, GF; Dota, CD; Ghiorghiu, D; Goldwater, R; Li, Y; Mellemgaard, A; Sahota, T; Verheijen, RB; Vik, T; Walker, S; Yan, W1
Ahmed, GF; Harmer, AR; Sahota, T; Schalkwijk, S; Verheijen, RB1
Bruderer, S; Darpo, B; Dingemanse, J; Hoch, M; Kaufmann, P; Remenova, T; Stoltz, R; Zhou, M1

Trials

3 trial(s) available for pyrazines and Long QT Syndrome

ArticleYear
A Randomized, Double-Blind, Placebo- and Positive-Controlled, Three-Way Crossover Study in Healthy Participants to Investigate the Effect of Savolitinib on the QTc Interval.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:5

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Protein Kinase Inhibitors; Pyrazines; Triazines

2021
Parent and Metabolite Concentration-QT Modeling to Evaluate QT-Interval Prolongation at Savolitinib Therapeutic Doses.
    The AAPS journal, 2021, 03-17, Volume: 23, Issue:3

    Topics: Double-Blind Method; Electrocardiography; Healthy Volunteers; Heart Rate; Humans; Inhibitory Concentration 50; Long QT Syndrome; Male; Middle Aged; Models, Biological; Protein Kinase Inhibitors; Pyrazines; Triazines

2021
A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Acetamides; Administration, Oral; Adolescent; Adult; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Placebos; Pyrazines; Receptors, Epoprostenol; Receptors, Prostaglandin; Young Adult

2015

Other Studies

1 other study(ies) available for pyrazines and Long QT Syndrome

ArticleYear
Anticancer drugs and COVID-19 antiviral treatments in patients with cancer: What can we safely use?
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 136

    Topics: Amides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Immunological; Antiviral Agents; Betacoronavirus; Chemical and Drug Induced Liver Injury; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Histone Deacetylase Inhibitors; Humans; Hydroxychloroquine; Immunosuppression Therapy; Kidney Diseases; Long QT Syndrome; Lopinavir; Neoplasms; Pandemics; Pneumonia, Viral; Poly(ADP-ribose) Polymerase Inhibitors; Proteasome Inhibitors; Protein Kinase Inhibitors; Pyrazines; Ritonavir; SARS-CoV-2

2020