pyrazines has been researched along with Leukemia P388 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailly, C; Baldeyrou, B; Blanchard, S; Caubère, P; Colson, P; Guillaumet, G; Houssier, C; Kraus-Berthier, L; Léonce, S; Pfeiffer, B; Pierré, A; Renard, P; Rodriguez, I; Tardy, C | 1 |
| Chimirri, A; Fenech, G; Grasso, S; Monforte, P | 1 |
| Adamson, DJ; Bowdon, BJ; Temple, C; Webster, J; Wheeler, GP | 1 |
| Comber, RN; Elliott, RD; Kussner, CL; Montgomery, JA; Rose, JD; Temple, C; Wheeler, GP | 1 |
| Chavan, SJ; Chitnis, MP; Mansuri-Torshizi, H; Srivastava, TS | 1 |
| Rener, GA; Temple, C | 2 |
| Griswold, DP; Harrison, SD; Temple, CG; Waud, WR | 1 |
| Comber, RN; Rener, GA; Temple, C; Waud, WR | 1 |
| Dykes, DJ; Griswold, DP; Harrison, SD; Plowman, J; Waud, WR | 1 |
10 other study(ies) available for pyrazines and Leukemia P388
| Article | Year |
|---|---|
Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dihydropyridines; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Leukemia P388; Mice; Pyrazines; Structure-Activity Relationship | 2004 |
[Compounds with presumable antitumor activity. III. 1-Substituted N,N'-di-2-pyrimidinyl (or pyrazinyl)methylenediamine].
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Diamines; Female; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Mice; Ovarian Neoplasms; Pyrazines; Pyrimidines; Rats | 1984 |
Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines.
Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Division; Cell Survival; Colchicine; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nocodazole; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1983 |
New anticancer agents: synthesis of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines).
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Leukemia L1210; Leukemia P388; Mice; Mitosis; Pyrazines; Pyridines | 1982 |
Cytotoxicity and DNA binding studies of several platinum (II) and palladium (II) complexes of the 2,2'-bipyridine and an anion of 2-pyridinecarboxylic/2-pyrazinecarboxylic acid.
Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Leukemia P388; Palladium; Platinum; Pyrazines; Pyridines; Spectrophotometry | 1992 |
Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4-hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7 -yl]carbamate.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Stereoisomerism; Structure-Activity Relationship | 1992 |
Antitumor drug cross-resistance in vivo in a murine P388 leukemia resistant to ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7 - ylcarbamate 2-hydroxyethanesulfonate hydrate (NSC 370,147) 370147.
Topics: Animals; Antineoplastic Agents; Drug Resistance; Leukemia P388; Mice; Mice, Inbred BALB C; Pyrazines; Vincristine | 1992 |
Antimitotic agents. Alterations at the 2,3-positions of ethyl (5-amino-1,2-dihydropyrido[3,4-b]pyrazin-7-yl)carbamates.
Topics: Animals; Antineoplastic Agents; Carbamates; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Structure-Activity Relationship | 1991 |
Schedule dependence, activity against natural metastases, and cross-resistance of pyrazine diazohydroxide (sodium salt, NSC 361456) in preclinical models in vivo.
Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazines | 1990 |
New anticancer agents: chiral isomers of ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazine-7-car bamate .
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colchicine; Drug Synergism; Isomerism; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1989 |