pyrazines has been researched along with Leukemia L 1210 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chimirri, A; Fenech, G; Grasso, S; Monforte, P | 1 |
| Chiang, PK; Cory, JG; De Clercq, E; Kim, IK; Olsson, RA; Schneller, SW; Thompson, RD | 1 |
| Comber, RN; Elliott, RD; Montgomery, JA; Rose, JD; Temple, C; Wheeler, GP | 1 |
| Bertoni-Freddari, C; Giuli, C; Giunta, S; Muzzioli, M; Pieri, C | 1 |
| Adamson, DJ; Bowdon, BJ; Temple, C; Webster, J; Wheeler, GP | 1 |
| Comber, RN; Elliott, RD; Kussner, CL; Montgomery, JA; Rose, JD; Temple, C; Wheeler, GP | 1 |
| Hook, KE; Leopold, WR; Przybranowski, SA | 1 |
| Rener, GA; Temple, C | 4 |
| Comber, RN; Rener, GA; Temple, C; Waud, WR | 1 |
| Dykes, DJ; Griswold, DP; Harrison, SD; Plowman, J; Waud, WR | 1 |
| Bloch, A; Bobek, M; Cole, FE; Sharma, RA | 1 |
14 other study(ies) available for pyrazines and Leukemia L 1210
| Article | Year |
|---|---|
[Compounds with presumable antitumor activity. III. 1-Substituted N,N'-di-2-pyrimidinyl (or pyrazinyl)methylenediamine].
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Diamines; Female; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Mice; Ovarian Neoplasms; Pyrazines; Pyrimidines; Rats | 1984 |
Biological activity and a modified synthesis of 8-amino-3-beta-D-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine, an isomer of formycin.
Topics: Adenosine Deaminase; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Cell Division; Dogs; Formycins; Hydrolases; Isomerism; Leukemia L1210; Mice; Pyrazines; Triazoles; Vasodilation | 1984 |
1,2-Dihydropyrido[3,4-b]pyrazines: structure-activity relationships.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Leukemia L1210; Mice; Mitosis; Pyrazines; Pyridines; Structure-Activity Relationship | 1983 |
In vitro block of murine L 1210 leukemia cell growth by amiloride, an inhibitor of passive Na+ influx.
Topics: Amiloride; Animals; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Leukemia L1210; Male; Mice; Pyrazines; Sodium | 1983 |
Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines.
Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Division; Cell Survival; Colchicine; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nocodazole; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1983 |
New anticancer agents: synthesis of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines).
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Leukemia L1210; Leukemia P388; Mice; Mitosis; Pyrazines; Pyridines | 1982 |
Cellular transport of CI-980.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carbamates; Carrier Proteins; Cattle; CHO Cells; Cricetinae; Dipyridamole; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Leukemia L1210; Platelet Aggregation Inhibitors; Pyrazines; Pyridines; Stereoisomerism | 1996 |
Antimitotic agents: ring analogues and derivatives of ethyl [(S)-5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7- yl]carbamate.
Topics: Animals; Antineoplastic Agents; Cell Division; Cells, Cultured; Leukemia L1210; Pyrazines; Stereoisomerism; Structure-Activity Relationship; Urethane | 1992 |
Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4-hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7 -yl]carbamate.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Stereoisomerism; Structure-Activity Relationship | 1992 |
Antimitotic agents. Alterations at the 2,3-positions of ethyl (5-amino-1,2-dihydropyrido[3,4-b]pyrazin-7-yl)carbamates.
Topics: Animals; Antineoplastic Agents; Carbamates; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Structure-Activity Relationship | 1991 |
Potential antimitotic agents. Synthesis of some ethyl benzopyrazin-7-ylcarbamates, ethyl pyrido[3,4-b]pyrazin-7-ylcarbamates, and ethyl pyrido[3,4-e]-as-triazin-7-ylcarbamates.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia L1210; Molecular Structure; Pyrazines; Pyridines; Structure-Activity Relationship; Triazines | 1990 |
Schedule dependence, activity against natural metastases, and cross-resistance of pyrazine diazohydroxide (sodium salt, NSC 361456) in preclinical models in vivo.
Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazines | 1990 |
New anticancer agents: chiral isomers of ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazine-7-car bamate .
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colchicine; Drug Synergism; Isomerism; Leukemia L1210; Leukemia P388; Mice; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1989 |
Synthesis and biological activity of some imidazo(4,5-b)pyrazines and their ribonucleosides as purine analogs.
Topics: Animals; Burkitt Lymphoma; Cells; Cells, Cultured; Crystallography; Escherichia coli; Imidazoles; Inosine; Leukemia L1210; Mammary Neoplasms, Experimental; Methods; Mice; Oxides; Purines; Pyrazines; Ribonucleosides; Xanthine Oxidase | 1973 |