pyrazines has been researched along with Injury, Myocardial Reperfusion in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, JD; Ma, GS; Sheng, ZL; Wang, X; Zuo, PF; Zuo, Z | 1 |
| Begum, SS; Hausenloy, DJ; Mocanu, MM; Riksen, N; Theodorou, L; Whittington, HJ; Wynne, AM; Yellon, DM | 1 |
| Abdelghany, RH; Mahmoud, AA; Youssef, MI | 1 |
| Gao, Q; Huang, W; Su, M; Yang, Y; Zeng, Z; Zhu, B | 1 |
| Jiao, BM; Li, ZL; Qian, HJ; Su, L; Zheng, JS | 1 |
| Fang, ZX; Hao, ML; Ni, SR; Song, ZJ; Wang, FY; Wang, WT; Xie, KJ | 1 |
| He, Z; Liu, H; Liu, J; Liu, X; Zeng, Z; Zhou, W | 1 |
| Cheng, Y; Gong, JB; Jiang, SS; Lv, L; Xu, J | 1 |
| Cheng, Y; Gong, J; Jiang, S; Lv, L; Meng, Q; Xu, J | 1 |
| Deng, HW; Deng, PY; Hu, CP; Li, YJ; Zhou, Y | 1 |
| Chen, SY; Cheng, PY; Hsiao, G; Hwang, HR; Lee, YM | 1 |
| Davey, AK; Evans, AM; Li, Y; Wang, J; Xu, D; Zhang, S | 1 |
| Chen, HP; He, M; Huang, QR; Liu, D; Zeng, GH | 1 |
| Dneprovskaia, E; Doukas, J; Fine, RM; Hood, J; Kang, X; Lohse, D; Martin, M; Noronha, G; Palanki, MS; Soll, RM; Wrasidlo, W; Yee, S; Zhu, H | 1 |
| Goto, T; Kanashiro, M; Matsubara, T; Sakamoto, N | 1 |
| Fu, CJ; Zhang, JF; Zhao, GS | 1 |
| Curtis, MJ; Rees, SA | 1 |
| Funaya, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Shinozaki, Y | 1 |
| Maruyama, Y; Nakano, M; Ushiroda, S | 1 |
| Lin, LN; Wang, WT; Xu, ZJ | 1 |
| Shao, W; Zhang, W; Zhou, S | 1 |
2 trial(s) available for pyrazines and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
[Clinical study on ligustrazine in treating myocardial ischemia and reperfusion injury].
Topics: Adolescent; Adult; Female; Free Radical Scavengers; Glutathione Peroxidase; Heart Septal Defects; Heart Valve Diseases; Humans; Male; Malondialdehyde; Myocardial Reperfusion Injury; Pyrazines; Rheumatic Heart Disease; Superoxide Dismutase | 1997 |
[Clinical study of Astragalus injection plus ligustrazine in protecting myocardial ischemia reperfusion injury].
Topics: Adolescent; Adult; Astragalus Plant; Astragalus propinquus; Cardiopulmonary Bypass; Drugs, Chinese Herbal; Female; Heart Septal Defects, Ventricular; Heart Valve Prosthesis Implantation; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Reperfusion Injury; Pyrazines; Rheumatic Heart Disease | 2000 |
19 other study(ies) available for pyrazines and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy.
Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Cell Survival; Chromones; Creatine Kinase; L-Lactate Dehydrogenase; Male; Morpholines; Myocardial Reperfusion Injury; Myocytes, Cardiac; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley | 2019 |
Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner.
Topics: Adamantane; Animals; Cyclic AMP-Dependent Protein Kinases; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Heart; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitriles; Pyrazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glucagon; Severity of Illness Index; Signal Transduction; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2013 |
A new combination of sitagliptin and furosemide protects against remote myocardial injury induced by renal ischemia/reperfusion in rats.
Topics: Animals; Biomarkers; Caspase 3; Furosemide; Kidney; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Oxidative Stress; Pyrazines; Rats; Rats, Wistar; Sitagliptin Phosphate; Triazoles; Tumor Necrosis Factor-alpha | 2015 |
Effect of Salvia miltiorrhiza and ligustrazine injection on myocardial ischemia/reperfusion and hypoxia/reoxygenation injury.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Coronary Occlusion; Coronary Vessels; Creatine Kinase; Gene Expression Regulation; Humans; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Rats; Reperfusion Injury; Salvia miltiorrhiza; Signal Transduction | 2016 |
[The influence of JNK inhibitor on hemodynamics after ischemia/reperfusion injury to the heart in rats].
Topics: Animals; Anthracenes; Disease Models, Animal; Hemodynamics; JNK Mitogen-Activated Protein Kinases; Male; Myocardial Reperfusion Injury; Protein Kinase Inhibitors; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley | 2008 |
[Effect of ligustrazine and L-arginine on function of mitochondria in myocardium after ischemia/reperfusion injury of myocardium in rabbits].
Topics: Animals; Arginine; Calcium; Malondialdehyde; Mitochondria, Heart; Myocardial Reperfusion Injury; Pyrazines; Rabbits; Superoxide Dismutase | 2007 |
Pharmacokinetics of ligustrazine ethosome patch in rats and anti-myocardial ischemia and anti-ischemic reperfusion injury effect.
Topics: Animals; Area Under Curve; Blood Viscosity; Chi-Square Distribution; Fibrinolytic Agents; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tissue Distribution; Transdermal Patch | 2011 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction | 2012 |
Ligustrazine attenuates myocardial ischemia reperfusion injury in rats by activating the phosphatidylinositol 3-kinase/Akt pathway.
Topics: Animals; Creatine Kinase, MB Form; Enzyme Activation; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase | 2012 |
The protective effects of ligustrazine on ischemia-reperfusion and DPPH free radical-induced myocardial injury in isolated rat hearts.
Topics: Animals; Biphenyl Compounds; Cardiotonic Agents; Ligusticum; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phytotherapy; Picrates; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2004 |
Tetramethylpyrazine induces heme oxygenase-1 expression and attenuates myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Chemotaxis; Fibrinolytic Agents; Gene Expression; Heme Oxygenase-1; Humans; Ligusticum; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Superoxides | 2006 |
The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic Acids; Disease Models, Animal; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Heart Rate; Hydroxy Acids; Injections, Intravenous; Myocardial Infarction; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ventricular Fibrillation | 2007 |
Delayed protection of tetramethylpyrazine on neonatal rat cardiomyocytes subjected to anoxia-reoxygenation injury.
Topics: Alkaloids; Animals; Benzophenanthridines; Cell Survival; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione Peroxidase; HSP70 Heat-Shock Proteins; In Vitro Techniques; L-Lactate Dehydrogenase; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protein Kinase C; Pyrazines; Rats; Superoxide Dismutase; Vasodilator Agents | 2007 |
Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction.
Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Isoenzymes; Male; Models, Molecular; Myocardial Infarction; Myocardial Reperfusion Injury; Phenols; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pteridines; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Umbilical Veins; Vascular Endothelial Growth Factor A | 2007 |
Cypridina luciferin analog reduces the incidence of ischemia/reperfusion-induced ventricular fibrillation.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Electrocardiography; Heart; In Vitro Techniques; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Pyrazines; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Ventricular Fibrillation; Ventricular Function, Left | 1993 |
[Effect of ligustrazine on isolated myocardial ischemic reperfusion injury in rats].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 1993 |
Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Heart; Hemodynamics; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Pyrazines; Pyridines; Rabbits; Rats; Rats, Wistar; Ventricular Fibrillation | 1993 |
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline | 1997 |
Continuous detection of superoxide in situ during ischemia and reperfusion in the rabbit heart.
Topics: Animals; Coronary Circulation; Free Radicals; Hemodynamics; Imidazoles; Luminescent Measurements; Male; Myocardial Reperfusion Injury; Myocardium; Pyrazines; Rabbits; Superoxide Dismutase; Superoxides | 1997 |