pyrazines has been researched along with Hypoxia in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.36) | 18.7374 |
| 1990's | 16 (36.36) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 11 (25.00) | 24.3611 |
| 2020's | 6 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Abdul Wahab, S; Adnan, NA; Cheng, JT; Chidambaram, SK; Chow, TS; Chuah, CH; Hor, CP; Ker, HB; Lee, HG; Lee, KS; Mustafa, M; Ng, TK; Nordin, N; Ong, SM; Tee, TY; Zaid, M; Zaidan, NZ | 1 |
| Deng, H; Gao, Y; Lai, C; Li, G; Shen, X; Wang, L; Wang, N; Yu, H; Zhou, L; Zhou, W | 1 |
| Ershler, WB; Holbrook, ME | 1 |
| Fuchikami, C; Honda, Y; Kosugi, K; Kuramoto, K; Kuwano, K; Numakura, Y | 1 |
| Ang, BT; Cheng, HS; Chong, YK; Law, CLD; Low, ZYJ; Marvalim, C; Tan, NS; Tang, C; Zhu, P | 1 |
| Du, Y; Jiang, M; Li, X; Liu, Y; Lu, Y; Luo, L; Luo, Z; Peng, L; Qin, B; Shi, Y; You, J; Zhang, J; Zhu, C | 1 |
| Hebbel, RP; Hedlund, BE | 1 |
| Estepp, JH | 1 |
| Azab, AK; Azab, F; Buggio, M; de la Puente, P; Fiala, M; Muz, B; Pachter, JA; Padval, MV; Vij, R; Weaver, DT | 1 |
| Lei, SY; Liu, Y; Ma, LQ; Mao, T; Qiao, Y; Sun, XL; Zhang, JC; Zheng, QX | 1 |
| Eba, S; Hoshikawa, Y; Ishida, K; Kondo, T; Mitsuishi, Y; Moriguchi, T; Okada, Y; Satoh, H; Shimizu, T; Shimokawa, H; Watanabe, T; Yamamoto, M | 1 |
| Borzym-Kluczyk, M; Cechowska-Pasko, M; Krętowski, R | 1 |
| Koc, M; Polak, J; Seda, O; Shimoda, LA; Weiszenstein, M | 1 |
| Chen, J; Raj, JU; Ramchandran, R; Sun, M; Yang, Q | 1 |
| Gao, X; Ma, W; Wang, Y; Zhang, X; Zhong, M | 1 |
| De Meester, I; Lambeir, AM; Scharpé, S | 1 |
| Befani, CD; Bonanou, S; Hatzidaki, E; Liakos, P; Papandreou, CN; Patrikidou, A; Simos, G; Vlachostergios, PJ | 1 |
| Chen, L; Ding, Y; Hou, X; Li, H; Tang, Y; Zhao, S; Zheng, Y; Zhou, H | 1 |
| Chen, L; Hu, HY; Li, L; Li, ZC; Ma, YQ; Yan, HX; Yang, WX; Zheng, Y | 1 |
| Chen, L; Hu, HY; Li, L; Li, ZC; Yan, HX; Yang, WX; Zheng, Y | 1 |
| Kaluz, S; Kaluzová, M; Stanbridge, EJ | 1 |
| Duan, SF; Jin, XQ; Niu, RJ | 1 |
| Cao, W; Luo, W; Zeng, Z | 1 |
| Sun, R; Wang, D; Xu, J; Zhang, H; Zhang, S | 1 |
| Cao, W; Guo, Z; Luo, W | 1 |
| MacKenzie, I; Saville, VL; Waterfall, JF | 1 |
| Arnal, F; Hill, NS; Klinger, JR; Petit, RD; Warburton, RR; Wrenn, DS | 1 |
| Feng, J; Liu, R; Tang, S; Wu, G | 1 |
| Andronati, SA; Dyadenko, AI; Korotenko, TI; Mazurov, AA; Shapiro, YE; Sokolenko, NI; Voronina, TA | 1 |
| Cao, W; Demura, H; Luo, W; Naruse, M; Shi, Y; Zeng, Z; Zhu, YJ | 1 |
| Chen, X; Sun, R; Yan, Y | 1 |
| Jeffery, TK; Wanstall, JC | 1 |
| Wang, D; Wei, M; Zhang, H; Zhao, S | 1 |
| Abbott, BM; Barthlow, HG; Bialecki, RA; Caccese, RG; Fisher, CS; Rumsey, J; Rumsey, W; Stow, RB | 1 |
| Auguet, M; Chabrier, PE; Demerlé-Pallardy, C; Gillard-Roubert, V; Marin, JG | 1 |
| Chen, S; Wang, L; Xu, Z | 1 |
| Baskin, EP; Brookes, LM; Claremon, DA; Lynch, JJ; Selnick, HG; Serik, CM; Wallace, AA | 1 |
| Barer, G; Bee, D; Emery, C; Oddoy, A | 1 |
| Chen, BH | 1 |
| Barer, GR; Cai, YN | 1 |
| Barer, G; Bee, D; Cai, YN | 1 |
| Barer, GR; Cai, YN; Emery, CJ; Russell, PC | 1 |
| Yuan, XJ | 1 |
| Wang, DX; Wu, F; Zou, AP | 1 |
1 review(s) available for pyrazines and Hypoxia
| Article | Year |
|---|---|
DPP4 inhibitors for diabetes--what next?
Topics: Adamantane; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Hypoxia; Neoplasms; Nitriles; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2008 |
1 trial(s) available for pyrazines and Hypoxia
| Article | Year |
|---|---|
Efficacy of Early Treatment With Favipiravir on Disease Progression Among High-Risk Patients With Coronavirus Disease 2019 (COVID-19): A Randomized, Open-Label Clinical Trial.
Topics: Amides; COVID-19 Drug Treatment; Disease Progression; Female; Humans; Hypoxia; Middle Aged; Pyrazines; SARS-CoV-2; Treatment Outcome | 2022 |
42 other study(ies) available for pyrazines and Hypoxia
| Article | Year |
|---|---|
Quantification of Acipimox in Plasma and Tissues by LC-MS/MS: Application to Pharmacokinetic Comparison between Normoxia and Hypoxia.
Topics: Animals; Chromatography, Liquid; Fatty Acids, Nonesterified; Hypolipidemic Agents; Hypoxia; Pyrazines; Rats; Tandem Mass Spectrometry | 2022 |
Sickle cell anemia and COVID-19: Use of voxelotor to avoid transfusion.
Topics: Adult; Anemia, Sickle Cell; Benzaldehydes; Combined Modality Therapy; COVID-19; COVID-19 Nucleic Acid Testing; Erythrocyte Transfusion; Female; Hematologic Agents; Hemoglobins; Humans; Hypoxia; Pyrazines; Pyrazoles | 2020 |
The selective PGI2 receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetamides; Animals; Cell Proliferation; Collagen Type I; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Lung; Male; Pulmonary Arterial Hypertension; Pyrazines; Pyrroles; Rats, Sprague-Dawley; Receptors, Epoprostenol; Systole; Vascular Remodeling | 2020 |
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Hypoxia; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-met; Pyrazines; Pyrrolidinones; Quinolines; Signal Transduction; Temozolomide; Transcriptome; Triazoles | 2021 |
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Topics: Endoplasmic Reticulum Stress; Humans; Hypoxia; Imidazoles; Immunotherapy; Macrophages; Naphthalenes; Oxidative Stress; Pyrazines | 2021 |
Sickle hemoglobin oxygen affinity-shifting strategies have unequal cerebrovascular risks.
Topics: 2,3-Diphosphoglycerate; Anemia, Sickle Cell; Benzaldehydes; Cerebrovascular Circulation; Cerebrovascular Disorders; Erythrocytes, Abnormal; Hematocrit; Hematologic Agents; Hemoglobin, Sickle; Hemolysis; Humans; Hypoxia; Microcirculation; Models, Biological; Organ Specificity; Oxygen; Oxyhemoglobins; Polymerization; Protein Binding; Pyrazines; Pyrazoles; Risk Assessment | 2018 |
Voxelotor (GBT440), a first-in-class hemoglobin oxygen-affinity modulator, has promising and reassuring preclinical and clinical data.
Topics: Adult; Anemia, Sickle Cell; Animals; Benzaldehydes; Cerebrovascular Circulation; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Erythropoietin; Gene Knock-In Techniques; Hematologic Agents; Hemoglobin, Sickle; Humans; Hypoxia; Mice; Mice, Transgenic; Oxygen; Polymerization; Pyrazines; Pyrazoles; Reticulocytes | 2018 |
PYK2/FAK inhibitors reverse hypoxia-induced drug resistance in multiple myeloma.
Topics: Aminopyridines; Benzamides; Drug Resistance, Neoplasm; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Humans; Hypoxia; Multiple Myeloma; Proteasome Inhibitors; Pyrazines; Sulfonamides; Tumor Cells, Cultured | 2019 |
[Intervention effects and mechanism of Chinese herbal medicine of supplementing Qi and activating blood circulation on chronic intermittent hypoxia composite insulin resistance ApoE~(-/-) mice model].
Topics: Animals; Atherosclerosis; Blood Circulation; Drugs, Chinese Herbal; Ginsenosides; Hypoxia; Insulin Resistance; Mice; Mice, Knockout, ApoE; Pyrazines; Qi; Random Allocation | 2019 |
The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anticarcinogenic Agents; Cytoskeletal Proteins; Disease Models, Animal; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Knockout; NF-E2-Related Factor 2; Pulmonary Disease, Chronic Obstructive; Pyrazines; Tenascin; Thiones; Thiophenes | 2013 |
Efficient induction of apoptosis by proteasome inhibitor: bortezomib in the human breast cancer cell line MDA-MB-231.
Topics: Antineoplastic Agents; Apoptosis; beta-Galactosidase; Boronic Acids; Bortezomib; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Female; Fibroblasts; HSP70 Heat-Shock Proteins; Humans; Hypoxia; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines | 2014 |
Inhibition of Lipolysis Ameliorates Diabetic Phenotype in a Mouse Model of Obstructive Sleep Apnea.
Topics: Adipocytes; Adiposity; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Fatty Acids; Gene Expression Regulation; Glucose; Hypoxia; Insulin; Lipolysis; Male; Mice, Inbred C57BL; Phenotype; Pyrazines; Signal Transduction; Sleep Apnea, Obstructive | 2016 |
Smooth Muscle Insulin-Like Growth Factor-1 Mediates Hypoxia-Induced Pulmonary Hypertension in Neonatal Mice.
Topics: Animals; Animals, Newborn; Blood Pressure; Cell Proliferation; Chronic Disease; Gene Deletion; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Insulin-Like Growth Factor I; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Myocytes, Smooth Muscle; Organ Specificity; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Pyrazines; Receptor, IGF Type 1; RNA, Messenger; Systole; Up-Regulation; Vascular Remodeling | 2016 |
Tetramethyl Pyrazine Protects Hippocampal Neurons Against Anoxia/Reoxygenation Injury Through Inhibiting Apoptosis Mediated by JNK/MARK Signal Pathway.
Topics: Animals; Anthracenes; Apoptosis; Cells, Cultured; Hippocampus; Hypoxia; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neurons; Neuroprotective Agents; Oxygen; Phosphorylation; Pyrazines; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Nucleus; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrazines; Signal Transduction; TOR Serine-Threonine Kinases; Transcription, Genetic | 2012 |
Protective action of tetramethylpyrazine on the medulla oblongata in rats with chronic hypoxia.
Topics: Animals; Apoptosis; Atmosphere Exposure Chambers; bcl-2-Associated X Protein; Gene Expression Regulation; Hypoxia; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Lipid Peroxidation; Male; Medulla Oblongata; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2013 |
[Effect of tetramethylpyrazine on the responses of respiration and expression of nNOS in brainstem to hypoxia in rats].
Topics: Animals; Brain Stem; Female; Hypoxia; Male; Nitric Oxide Synthase Type I; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Insufficiency | 2005 |
[Protective effect of tetramethylpyrazine on the respiratory inhibition induced by hypoxia in rats].
Topics: Animals; Brain Stem; Female; Hypoxia; Male; Protective Agents; Proto-Oncogene Proteins c-fos; Pyrazines; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Insufficiency | 2005 |
Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain.
Topics: Animals; Biomarkers; Boronic Acids; Bortezomib; Carbonic Anhydrases; Cell Line; Enzyme Activation; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; p300-CBP Transcription Factors; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Structure, Tertiary; Pyrazines; Recombinant Fusion Proteins; Transcription, Genetic; Vascular Endothelial Growth Factor A | 2006 |
[Effect of shen mai injection and its combinations on blood gas and hemodynamics of rats exposed to chronic hypoxia].
Topics: Animals; Blood Gas Analysis; Cardiac Output; Drugs, Chinese Herbal; Hypoxia; Injections, Intravenous; Male; Panax; Plants, Medicinal; Pyrazines; Rats; Rats, Wistar; Vascular Resistance | 1995 |
[The effect of acute pulmonary alveolar hypoxia on canine plasma endothelin-1 levels].
Topics: Animals; Calcium Channel Blockers; Dogs; Endothelins; Female; Hypertension, Pulmonary; Hypoxia; Male; Pyrazines | 1994 |
[Experimental study on acute hypoxia in newborn rabbits].
Topics: Acute Disease; Animals; Animals, Newborn; Blood Pressure; Calcium Channel Blockers; Dura Mater; Female; Hypoxia; Male; Microcirculation; Pulmonary Artery; Pyrazines; Rabbits; Solanaceous Alkaloids | 1995 |
[Effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension in anesthetized dogs].
Topics: Acute Disease; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Hypertension, Pulmonary; Hypoxia; Male; Methylene Blue; Nitroglycerin; Pyrazines; Vascular Resistance | 1994 |
Differential class III and glibenclamide effects on action potential duration in guinea-pig papillary muscle during normoxia and hypoxia/ischaemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrophysiology; Glyburide; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Microelectrodes; Myocardial Ischemia; Papillary Muscles; Piperidines; Potassium Channels; Pyrazines; Pyridines; Sotalol | 1993 |
Neutral endopeptidase inhibition attenuates development of hypoxic pulmonary hypertension in rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Cyclic GMP; Dioxolanes; Dipeptides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Male; Muscle, Smooth, Vascular; Myocardium; Neprilysin; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |
Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Coronary Circulation; Epoprostenol; Heart; Hypoxia; In Vitro Techniques; Male; Myocardium; Perfusion; Platelet Aggregation Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane B2; Time Factors; Vasodilator Agents | 1997 |
TRH mimetics: differentiation of antiamnesic potency from antidepressant effect.
Topics: Amino Acid Sequence; Amnesia; Animals; Antidepressive Agents; Azocines; Electroencephalography; Hypoxia; Magnetic Resonance Spectroscopy; Mice; Molecular Sequence Data; Protein Conformation; Pyrazines; Pyrroles; Rats; Thyrotropin-Releasing Hormone | 1997 |
Effects of tetramethylpyrazine, a Chinese medicine, on plasma endothelin-1 levels during acute pulmonary hypoxia in anesthetized dogs.
Topics: Anesthesia, General; Animals; Blood Pressure; Dogs; Drugs, Chinese Herbal; Endothelin-1; Hemodynamics; Hypoxia; Lung Diseases; Pulmonary Alveoli; Pulmonary Circulation; Pyrazines; Vascular Resistance; Vasodilator Agents | 1998 |
[Effect of 764-3 and ligustrazine on collagen content of extrapulmonary arteries during chronic hypoxia].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Drugs, Chinese Herbal; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Pyrazines; Rats; Rats, Wistar | 1996 |
Phosphodiesterase III and V inhibitors on pulmonary artery from pulmonary hypertensive rats: differences between early and established pulmonary hypertension.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Hypertension, Pulmonary; Hypoxia; Imidazoles; Male; Milrinone; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Pyrazines; Pyridones; Rats; Rats, Wistar; Vasodilation | 1998 |
[Prophylactic effects of magnesium sulfate and ligustrazin on the hypoxic-ischemic brain damage in neonatal rats].
Topics: Animals; Animals, Newborn; Brain Ischemia; Calcium Channel Blockers; Cerebral Cortex; Female; Hypoxia; Magnesium Sulfate; Male; Malondialdehyde; Neurons; Pyrazines; Rats; Rats, Wistar; Superoxide Dismutase | 1997 |
ZD1611, an orally active endothelin-A receptor antagonist, prevents chronic hypoxia-induced pulmonary hypertension in the rat.
Topics: Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Hematocrit; Hypertension, Pulmonary; Hypoxia; Isometric Contraction; Male; Muscle, Smooth, Vascular; Organ Size; Pulmonary Artery; Pulmonary Circulation; Pyrazines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sulfonamides; Ventricular Function, Right | 1999 |
In vitro antioxidant neuroprotective activity of BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation.
Topics: Animals; Antioxidants; Cell Line; Cerebral Cortex; Dinoprost; Enzyme Inhibitors; F2-Isoprostanes; Glutathione; Hypoxia; L-Lactate Dehydrogenase; Lipid Peroxides; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Pyrazines; Rats; Rats, Wistar; Thiophenes | 2000 |
[Effect of hypoxic hypercapnia on expression of endothelin-1 mRNA of pulmonary arterioles in rats].
Topics: Animals; Arterioles; Endothelin-1; Hypercapnia; Hypoxia; Male; Pulmonary Artery; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2000 |
Effects of new and potent methanesulfonanilide class III antiarrhythmic agents on myocardial refractoriness and contractility in isolated cardiac muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Ferrets; Heart; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Piperidines; Pyrazines; Pyridines; Refractory Period, Electrophysiological; Sotalol; Sulfonamides; Temperature | 1991 |
Effects of ligustrazine on the pressure/flow relationship in isolated perfused rat lungs.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyrazines; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1991 |
[Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats].
Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Male; Penicillamine; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1990 |
Effect of ligustrazine on pulmonary vascular changes induced by chronic hypoxia in rats.
Topics: Animals; Blood Pressure; Chronic Disease; Hypertension, Pulmonary; Hypoxia; Pulmonary Artery; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1989 |
Pulmonary vasodilator action of ligustrazine, active principle of a traditional Chinese remedy, in rats and ferrets.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Ferrets; Hypoxia; In Vitro Techniques; Male; Pulmonary Artery; Pyrazines; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1989 |
Reactivity and site of vasomotion in pulmonary vessels of chronically hypoxic rats: relation to structural changes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Almitrine; Angiotensin I; Animals; Bradykinin; Chronic Disease; Hypoxia; Male; Platelet Activating Factor; Pulmonary Circulation; Pyrazines; Rats; Rats, Inbred Strains; Reference Values; Respiration; Vasoconstriction; Vasodilator Agents; Vasomotor System | 1989 |
[Inhibitory effect of ligustrazine on acute and chronic pulmonary hypertension in rats].
Topics: Animals; Calcium Channel Blockers; Hemodynamics; Hyperbaric Oxygenation; Hypertension, Pulmonary; Hypoxia; Pyrazines; Rats; Rats, Inbred Strains | 1988 |
Effect of tetramethylpyrazine on acute and chronic hypoxic pulmonary hypertension of the rat.
Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1986 |