Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and Hyperactivity, Motor

pyrazines has been researched along with Hyperactivity, Motor in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cilia, J; Cluderay, JE; Dawson, LA; Gartlon, JE; Jennings, CA; Jones, DN; Lacroix, LP; Medhurst, AD; Reavill, C; Rourke, C; Southam, E; Wilson, DM; Woolley, ML1
Brandon, NJ; Brennan, J; Egerland, U; Erdei, J; Fan, KY; Graf, R; Grauer, S; Grunwald, C; Hage, T; Harrison, BL; Hoefgen, N; Kronbach, T; Langen, B; Lankau, HJ; Malamas, MS; Marquis, KL; Navarra, R; Ni, Y; Pangalos, MN; Parris, K; Robichaud, A; Schindler, R; Stange, H1
Bubar, MJ; Cunningham, KA; Filip, M1
Brown, J; Chapin, DS; Chiang, P; Guanowsky, V; Iredale, PA; Marala, R; McCarthy, SA; Patterson, T; Seymour, PA; Siuciak, JA; Swick, A1
Baldessarini, RJ; Tarazi, FI; Zhang, K1
Cunningham, KA; Filip, M1

Other Studies

6 other study(ies) available for pyrazines and Hyperactivity, Motor

ArticleYear
Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040.
    Psychopharmacology, 2009, Volume: 201, Issue:4

    Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Dose-Response Relationship, Drug; Histamine Antagonists; Hyperkinesis; Male; Memory; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Recognition, Psychology; Schizophrenia; Social Isolation

2009
Highly potent, selective, and orally active phosphodiesterase 10A inhibitors.
    Journal of medicinal chemistry, 2011, Nov-10, Volume: 54, Issue:21

    Topics: Administration, Oral; Animals; Antipsychotic Agents; Avoidance Learning; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Dogs; Female; Humans; Hydrolysis; Hyperkinesis; In Vitro Techniques; Isoenzymes; Ligands; Male; Mice; Microsomes; Models, Molecular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Conformation; Pyrazines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recombinant Proteins; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship

2011
Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:3

    Topics: Amphetamines; Animals; Cocaine; Drug Interactions; Fluorobenzenes; Hyperkinesis; Indoles; Male; Phenols; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

2004
CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Amphetamines; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Catalepsy; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Helplessness, Learned; Humans; Hyperkinesis; Inhibition, Psychological; Male; Mice; Motor Activity; NIH 3T3 Cells; Piperazines; Protein Binding; Psychotic Disorders; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists

2007
Role of dopamine D(4) receptors in motor hyperactivity induced by neonatal 6-hydroxydopamine lesions in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5

    Topics: Animals; Animals, Newborn; Autoradiography; Central Nervous System Stimulants; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Hyperkinesis; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Pyrazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D4; Sympatholytics

2001
Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4

    Topics: Animals; Cocaine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylamines; Hyperkinesis; Indoles; Male; Microinjections; Motor Activity; Nucleus Accumbens; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides

2002