pyrazines has been researched along with Grippe in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 11 (36.67) | 24.3611 |
| 2020's | 15 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaszynski, RH; Matsumoto, S; Sakai, K; Sato, N; Shiraki, K; Takemoto, M | 1 |
| Epstein, C; Hayden, FG; Kang, LL; Lenk, RP; Oldham-Creamer, C; Stonis, L | 1 |
| Furuta, Y; Komeno, T; Morinaga, Y; Nakajima, N; Tani, H | 1 |
| Cao, B; Chen, C; Fan, G; Guo, L; Hayden, FG; Horby, P; Lu, B; Pan, J; Salam, A; Wang, C; Wang, Y; Zheng, J | 1 |
| Martin-Loeches, I; O'Sullivan, S; Rodriguez, A; Torres, A | 1 |
| Plemper, RK; Toots, M | 1 |
| Daikoku, T; Shiraki, K | 1 |
| Takashita, E | 1 |
| Best, T; Breuer, J; Illingworth, CJR; Lumby, CK; Oporto, M; Shah, D; Tutill, H; Veys, P; Williams, R; Worth, A; Zhao, L | 1 |
| Cheng, YH; Fang, QQ; Huang, WJ; Li, XY; Liu, J; Meng, Y; Tan, MJ; Wang, DY; Wei, HJ | 1 |
| Chen, K; Couban, RJ; Du, X; Gong, X; Guyatt, G; He, N; Ibrahim, QI; Li, X; Li, Y; Liu, F; Liu, J; Liu, W; Shen, N; Tang, Q; Wu, Z; Xu, X; Ye, Z; Ying, Y; Zhai, S; Zhang, Q; Zhang, Y; Zhou, P | 1 |
| Ikeda, T; Kondo, Y; Miyazaki, S; Yamashita, R | 1 |
| Ison, MG; Scheetz, MH | 1 |
| Akinbami, O; Barclay, WS; Frise, R; Galiano, M; Gallego Cortés, A; Goldhill, DH; Lackenby, A; Miah, S; Shelley, J; Yan, A; Zambon, M; Zhou, J | 1 |
| Cheung, PP; Chong, TH; Huang, X; Wang, Y; Xu, X; Yuan, C; Zhang, L | 1 |
| Favié, LM; Meijer, A; Murk, JL; Nijstad, AL; Sikma, MA; van Maarseveen, EM | 1 |
| Barnard, DL; Furuta, Y; Gowen, BB; Shiraki, K; Smee, DF; Takahashi, K | 1 |
| Barnard, DL; Furuta, Y; Hurst, BL; Smee, DF; Tarbet, EB; Vollmer, AH | 1 |
| Cheong, HJ; Choi, WS; Kim, WJ; Noh, JY; Song, JY | 1 |
| Ejima, M; Fujisaki, S; Furuta, Y; Kawaoka, Y; Neumann, G; Odagiri, T; Ogawa, R; Takashita, E; Tashiro, M | 1 |
| Yen, HL | 1 |
| Azuma, T; Hisamatsu, K; Hosomaru, K; Ishida, M; Kunitou, M; Mikata, S; Mino, Y; Otomo, K; Shimizu, M; Yunoki, A | 1 |
| Reina, J; Reina, N | 1 |
| Hayden, F | 1 |
| Furuta, Y; Kawaoka, Y; Kiso, M; Le, QM; Ozawa, M; Sakabe, S; Sakai-Tagawa, Y; Shinya, K; Takahashi, K | 1 |
| Deyde, VM; Furuta, Y; Gubareva, LV; Klimov, AI; Mishin, VP; Sleeman, K | 1 |
| Babu, YS; Furuta, Y; Maekawa, M; Morrey, JD; Smee, DF; Tarbet, EB | 1 |
| Bailey, KW; Barnard, DL; Day, CW; Furuta, Y; Morrey, JD; Sidwell, RW; Smee, DF; Wong, MH | 1 |
| Bergey, G; Bielekova, B; Clarence-Smith, K; Dhib-Jalbut, S; Jiang, H; Johnson, KP; Martin, R; Okazaki, H | 1 |
| Egawa, H; Fukuda, Y; Furuta, Y; Kamiyama, T; Kozaki, K; Kuno, M; Minami, S; Narita, H; Nomura, N; Shiraki, K; Takahashi, K; Watanabe, Y | 1 |
11 review(s) available for pyrazines and Grippe
| Article | Year |
|---|---|
Antiviral therapy for COVID-19: Derivation of optimal strategy based on past antiviral and favipiravir experiences.
Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; COVID-19 Testing; Cytomegalovirus Infections; Humans; Influenza, Human; Pyrazines; SARS-CoV-2 | 2022 |
Influenza management with new therapies.
Topics: Adrenal Cortex Hormones; Amides; Antiviral Agents; Critical Care; Critical Illness; Dibenzothiepins; Enzyme Inhibitors; Humans; Influenza, Human; Morpholines; Neuraminidase; Oseltamivir; Pyrazines; Pyridines; Pyridones; Pyrimidines; Pyrroles; Respiration, Artificial; Triazines; Zanamivir | 2020 |
Next-generation direct-acting influenza therapeutics.
Topics: Amides; Antibodies, Neutralizing; Antiviral Agents; Cytidine; Dibenzothiepins; Drug Resistance, Viral; Humans; Hydroxylamines; Influenza, Human; Morpholines; Neuraminidase; Oxazines; Pyrazines; Pyridines; Pyridones; Ribonucleosides; RNA-Dependent RNA Polymerase; Thiepins; Triazines; Virus Replication | 2020 |
Favipiravir, an anti-influenza drug against life-threatening RNA virus infections.
Topics: Amides; Animals; Antiviral Agents; Humans; Influenza, Human; Pyrazines; RNA Virus Infections | 2020 |
Influenza Polymerase Inhibitors: Mechanisms of Action and Resistance.
Topics: Amides; Antiviral Agents; Dibenzothiepins; Drug Resistance, Viral; Humans; Influenza, Human; Morpholines; Orthomyxoviridae; Pyrazines; Pyridines; Pyridones; Pyrimidines; Pyrroles; RNA-Dependent RNA Polymerase; Triazines; Virus Replication | 2021 |
Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARS-CoV-2 and other acute viral infections: a systematic review and meta-analysis.
Topics: Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Evidence-Based Medicine; Humans; Hydroxychloroquine; Indoles; Influenza, Human; Lopinavir; Observational Studies as Topic; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2 | 2020 |
Favipiravir (T-705), a novel viral RNA polymerase inhibitor.
Topics: Amides; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Humans; Influenza, Human; Japan; Pyrazines; RNA Viruses; United States | 2013 |
Antiviral therapy in seasonal influenza and 2009 H1N1 pandemic influenza: Korean experiences and perspectives.
Topics: Acids, Carbocyclic; Amides; Antiviral Agents; Clinical Trials as Topic; Cyclopentanes; Drug Resistance, Viral; Guanidines; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pyrans; Pyrazines; Republic of Korea; Sialic Acids; Zanamivir | 2015 |
Current and novel antiviral strategies for influenza infection.
Topics: Amides; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Nucleoproteins; Pyrazines; Respiratory Tract Infections; Virus Replication | 2016 |
[Favipiravir, a new concept of antiviral drug against influenza viruses].
Topics: Amides; Animals; Antiviral Agents; Humans; Influenza, Human; Orthomyxoviridae; Pyrazines | 2017 |
Developing new antiviral agents for influenza treatment: what does the future hold?
Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cyclopentanes; Drug Discovery; Drug Resistance, Viral; Drug Therapy, Combination; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Pyrazines; Recombinant Fusion Proteins; Zanamivir | 2009 |
1 trial(s) available for pyrazines and Grippe
| Article | Year |
|---|---|
Favipiravir Treatment of Uncomplicated Influenza in Adults: Results of Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Trials.
Topics: Adult; Antiviral Agents; Double-Blind Method; Fever; Humans; Influenza, Human; Pyrazines; RNA; Treatment Outcome | 2022 |
18 other study(ies) available for pyrazines and Grippe
| Article | Year |
|---|---|
Analysis of the responsible site for favipiravir resistance in RNA-dependent RNA polymerase of influenza virus A/PR/8/34 (H1N1) using site-directed mutagenesis.
Topics: Amides; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutagenesis, Site-Directed; Pyrazines; RNA-Dependent RNA Polymerase; Virus Replication; Viruses | 2022 |
Comparative Effectiveness of Combined Favipiravir and Oseltamivir Therapy Versus Oseltamivir Monotherapy in Critically Ill Patients With Influenza Virus Infection.
Topics: Aged; Amides; Antiviral Agents; Critical Illness; Drug Therapy, Combination; Female; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Pyrazines; Retrospective Studies | 2020 |
Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child.
Topics: Amides; Antiviral Agents; Child; Humans; Influenza, Human; Pyrazines; Zanamivir | 2020 |
Effectiveness of favipiravir (T-705) against wild-type and oseltamivir-resistant influenza B virus in mice.
Topics: Amides; Animals; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Influenza B virus; Influenza, Human; Mice; Mice, Inbred C57BL; Oseltamivir; Pyrazines | 2020 |
Coinfection with SARS-CoV-2 and influenza A virus.
Topics: Amides; Anti-Bacterial Agents; Antiviral Agents; Betacoronavirus; Coinfection; Coronavirus Infections; COVID-19; Diagnosis, Differential; Glucocorticoids; Humans; Influenza A virus; Influenza, Human; Lung; Male; Middle Aged; Pandemics; Pneumonia, Viral; Pregnenediones; Pyrazines; Radiography; Real-Time Polymerase Chain Reaction; SARS-CoV-2 | 2020 |
Understanding the pharmacokinetics of Favipiravir: Implications for treatment of influenza and COVID-19.
Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Influenza, Human; Orthomyxoviridae; Pyrazines; SARS-CoV-2 | 2021 |
Favipiravir-resistant influenza A virus shows potential for transmission.
Topics: Amides; Animals; Antiviral Agents; Drug Resistance, Viral; Ferrets; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Orthomyxoviridae Infections; Pyrazines | 2021 |
The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription.
Topics: Amides; Humans; Influenza, Human; Pyrazines; Viral Transcription | 2021 |
Pharmacokinetics of favipiravir during continuous venovenous haemofiltration in a critically ill patient with influenza.
Topics: Amides; Antiviral Agents; Critical Illness; Fatal Outcome; Hemofiltration; Humans; Influenza, Human; Intensive Care Units; Male; Middle Aged; Netherlands; Oseltamivir; Pyrazines; Tertiary Care Centers | 2018 |
In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Drug Synergism; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Oseltamivir; Pyrazines | 2014 |
Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir.
Topics: Amides; Antiviral Agents; Cell Line; Cells, Cultured; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Microbial Sensitivity Tests; Neuraminidase; Orthomyxoviridae; Pyrazines; Viral Proteins | 2016 |
Fate of new three anti-influenza drugs and one prodrug in the water environment.
Topics: Acids, Carbocyclic; Amides; Antiviral Agents; Biodegradation, Environmental; Cyclopentanes; Environmental Monitoring; Fresh Water; Guanidines; Half-Life; Humans; Influenza, Human; Japan; Prodrugs; Pyrans; Pyrazines; Rivers; Seasons; Sewage; Sialic Acids; Water Pollutants, Chemical; Zanamivir | 2017 |
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses.
Topics: Aged; Amides; Animals; Antiviral Agents; Cell Line; Child; DNA Replication; DNA-Directed DNA Polymerase; Dogs; Drug Resistance, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Kidney; Kinetics; Lung; Oseltamivir; Pyrazines; Ribavirin | 2010 |
In vitro antiviral activity of favipiravir (T-705) against drug-resistant influenza and 2009 A(H1N1) viruses.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Humans; In Vitro Techniques; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H2N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Pyrazines; Swine; Viral Plaque Assay; Virus Replication | 2010 |
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice.
Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; California; Cyclopentanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mice; Mice, Inbred BALB C; Pandemics; Pyrazines | 2012 |
Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice.
Topics: Amides; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Oseltamivir; Oxygen; Pyrazines; Survival Analysis; Virus Replication | 2007 |
The effect of vesnarinone on TNF alpha production in human peripheral blood mononuclear cells and microglia: a preclinical study for the treatment of multiple sclerosis.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Influenza, Human; Interferon-gamma; Lipopolysaccharides; Microglia; Multiple Sclerosis; Pyrazines; Pyrrolidinones; Quinolines; Rolipram; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1999 |
In vitro and in vivo activities of anti-influenza virus compound T-705.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Drug Screening Assays, Antitumor; Humans; Influenza, Human; Lung; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Orthomyxoviridae; Pyrazines; Viruses | 2002 |