pyrazines has been researched along with Gastrointestinal Stromal Tumors in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbott, A; Belinsky, M; Chugh, R; Crowley, J; Flieder, DB; George, S; Heinrich, MC; Hornick, JL; Janeway, KA; Litwin, S; Rink, L; Schuetze, SM; Van den Abbeele, AD; von Mehren, M; Yap, JT; Yu, JQ | 1 |
| Chen, S; Chen, W; Dong, Y; He, X; Liang, C; Ma, J; Zhang, B; Zhang, X | 1 |
| Bauer, S; Brown, MF; Chatterjee, P; Chin, A; Duensing, A; Duensing, S; Fletcher, JA; Kuan, SF; Mühlenberg, T; Parry, JA; Rubin, BP; Seneviratne, D | 1 |
| Duensing, A; Duensing, S | 1 |
1 review(s) available for pyrazines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
Bortezomib: killing two birds with one stone in gastrointestinal stromal tumors.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Gastrointestinal Stromal Tumors; Histones; Humans; Proto-Oncogene Proteins c-kit; Pyrazines | 2010 |
1 trial(s) available for pyrazines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
Linsitinib (OSI-906) for the Treatment of Adult and Pediatric Wild-Type Gastrointestinal Stromal Tumors, a SARC Phase II Study.
Topics: Adolescent; Adult; Electron Transport Complex II; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imidazoles; Male; Middle Aged; Mutation; Patient Safety; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazines; Receptor, IGF Type 1; Treatment Outcome; Young Adult | 2020 |
2 other study(ies) available for pyrazines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
Bortezomib enhances the therapeutic efficacy of dasatinib by promoting c-KIT internalization-induced apoptosis in gastrointestinal stromal tumor cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptotic Protease-Activating Factor 1; Biomarkers, Tumor; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Proliferation; Dasatinib; Drug Synergism; Fluorescent Antibody Technique; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Immunoprecipitation; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Thiazoles; Tumor Cells, Cultured | 2015 |
Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Flow Cytometry; Fluorescent Antibody Technique; Gastrointestinal Stromal Tumors; Gene Expression; Histones; Humans; Immunoprecipitation; Proto-Oncogene Proteins c-kit; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2010 |