Page last updated: 2024-08-21

pyrazines and Edema

pyrazines has been researched along with Edema in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (44.44)	18.7374
1990's	3 (11.11)	18.2507
2000's	4 (14.81)	29.6817
2010's	8 (29.63)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, L; Liu, J; Liu, T; Wang, Q	1
El-Emary, T; El-Kashef, H; Samy, M; Vanelle, P; Verhaeghe, P	1
Chávez-Riveros, A; Hernández-Vázquez, E; Miranda, LD; Nieto-Camacho, A	1
Bastani, B; Fesler, M; Jasim, S; Mahmud, G	1
Hobeika, L; Self, SE; Velez, JC	1
Auguet, M; Chabrier, PE; Favre-Guilmard, C; Prevost, G; Soulard, C; Touvay, C; Zeroual-Hider, H	1
Mikhail, N	1
Alexandre-Moreira, MS; Augusto, CV; Barreiro, EJ; da Silva, YK; de Albuquerque Melo, GM; de Castro Barbosa, ML; de Lima Matos Freire Dias, T; de Queiroz, AC; Júnior, WB; Lima, LM	1
Appenzeller, M; Bigliardi, P; Buclin, T; Grouzmann, E; Pannatier, A	1
Mahé, E; Sigal, ML; Sin, C	1
Akhila, V; Daga, P; Hegde, P; Rao, CS; Rao, YK; Ravikumar, V; Rudrawar, SV; Saibaba, V; Singh, SK	1
Wang, F; Wang, J; Zhang, S	1
Berlind, S; Lundvall, O	1
Hellewell, PG; Rossi, AG; Teixeira, MM; Williams, TJ	1
Barbera, R; Grasso, S; Monforte, MT; Ottanà, R; Trovato, A; Vigorita, MG; Zappalà, M	1
Salvatore, C; Schena, FP; Vox, E	1
Corvol, P; Milliez, P; Thibonnier, M	1
Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E	1
Cleres-Kaiser, I	1
Danĕková, H; Dzúrik, R; Hlavatá, E	1
Abignente, E; Autore, G; Capasso, F; De Caprariis, P; Rimoli, MG	1
Gilly, R; Herne, N; Le Gall, F; Michaud, J; Roux, M	1
Kennedy, RD; MacFarlane, JP	1
Bancons, J; Dubarry, JJ; Quinton, A	1
Benoit, JP; Benoit, P	1
Cruz, HM; Cruz, J; Mattar, E	1
Grayer, D; Iber, F	1

Reviews

1 review(s) available for pyrazines and Edema

Article	Year
Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential. Vascular health and risk management, 2008, Volume: 4, Issue:6 Topics: Adamantane; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Edema; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Nitriles; Pioglitazone; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Thiazolidinediones; Treatment Outcome; Triazoles; Vildagliptin	2008

Article

Year

Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential.

Vascular health and risk management, 2008, Volume: 4, Issue:6

Topics: Adamantane; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Edema; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Nitriles; Pioglitazone; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Thiazolidinediones; Treatment Outcome; Triazoles; Vildagliptin

2008

Trials

5 trial(s) available for pyrazines and Edema

Article	Year
Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers. Biological chemistry, 2011, Volume: 392, Issue:3 Topics: Capsaicin; Carbonated Beverages; Cross-Over Studies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Edema; Erythema; Humans; Injections, Intradermal; Male; Pain; Pyrazines; Sitagliptin Phosphate; Skin; Substance P; Triazoles; Vasodilation	2011
[Effects of a potassium-sparing diuretic in cardiac edema and ascitic cirrhosis]. La Clinica terapeutica, 1977, Sep-15, Volume: 82, Issue:5 Topics: Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Pyrazines	1977
[Treatment of cardiac and hepatic edemas using the potassium-sparing diuretic Moduretic]. Die Medizinische Welt, 1975, Apr-18, Volume: 26, Issue:16 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Diseases; Male; Middle Aged; Pyrazines	1975
The effects of amiloride during diuretic therapy in elderly subjects. Age and ageing, 1972, Volume: 1, Issue:2 Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinations; Edema; Female; Humans; Hydrochlorothiazide; Hypokalemia; Male; Potassium; Pyrazines; Sodium; Urea; Uric Acid	1972
Acute effects of a new potassium-sparing diuretic, amiloride hidrochloride (MK-870), alone and in combination with acetazolamide in normal human subjects. AMB : revista da Associacao Medica Brasileira, 1969, Volume: 15, Issue:9 Topics: Acetazolamide; Clinical Trials as Topic; Diuretics; Drug Synergism; Edema; Electrolytes; Humans; Natriuresis; Potassium; Pyrazines; Time Factors; Water-Electrolyte Balance	1969

Other Studies

21 other study(ies) available for pyrazines and Edema

Article	Year
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo. BMC complementary and alternative medicine, 2017, Apr-27, Volume: 17, Issue:1 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspartate Aminotransferases; Cartilage; Curcumin; Cytokines; Drug Combinations; Edema; Female; Inflammation; Joints; Kidney; Liver; Male; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Pyrazines; Rats, Sprague-Dawley; Resveratrol; Stilbenes	2017
Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4- Molecules (Basel, Switzerland), 2018, Oct-16, Volume: 23, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Proliferation; Cell Survival; Edema; Heterocyclic Compounds, 1-Ring; Humans; MCF-7 Cells; Molecular Structure; Pyrazines; Pyrazoles; Rats	2018
A Two-Step Multicomponent Synthetic Approach and Anti-inflammatory Evaluation of N-Substituted 2-Oxopyrazines. ChemMedChem, 2019, 01-08, Volume: 14, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Ear; Edema; Inflammation; Male; Mice; Molecular Structure; Pyrazines; Structure-Activity Relationship	2019
Subcutaneous bortezomib for treatment of TEMPI syndrome. Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:6 Topics: Boronic Acids; Bortezomib; Edema; Female; Humans; Middle Aged; Paraproteinemias; Polycythemia; Proteasome Inhibitors; Pyrazines; Skin; Telangiectasis; Treatment Outcome	2014
Renal thrombotic microangiopathy and podocytopathy associated with the use of carfilzomib in a patient with multiple myeloma. BMC nephrology, 2014, Sep-30, Volume: 15 Topics: Acute Kidney Injury; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Disease Progression; Edema; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Hypertension, Renal; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Podocytes; Proteasome Inhibitors; Proteinuria; Pyrazines; Recurrence; Shock, Septic; Teniposide; Thalidomide; Thrombotic Microangiopathies	2014
The novel inhibitor of the heterotrimeric G-protein complex, BIM-46187, elicits anti-hyperalgesic properties and synergizes with morphine. European journal of pharmacology, 2008, Oct-10, Volume: 594, Issue:1-3 Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Constriction, Pathologic; Cyclohexanes; Drug Synergism; Edema; Heterotrimeric GTP-Binding Proteins; Hyperalgesia; Male; Morphine; Pain Measurement; Peripheral Nervous System Diseases; Psychomotor Performance; Pyrazines; Rats; Rats, Sprague-Dawley	2008
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates. Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Ear; Edema; Female; Freund's Adjuvant; Hydrazones; Male; Mice; Pain; Peritonitis; Pyrazines; Rats; Rats, Wistar; Zymosan	2010
Drug reaction with eosinophilia and systemic symptoms (DRESS) in a patient taking sitagliptin. Diabetes & metabolism, 2012, Volume: 38, Issue:6 Topics: Acute Kidney Injury; Aged; Back; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Ear; Edema; Eosinophilia; Exanthema; Female; Glucocorticoids; Humans; Prednisone; Pyrazines; Sitagliptin Phosphate; Triazoles	2012
Synthesis and biological evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors. Bioorganic & medicinal chemistry, 2004, Apr-15, Volume: 12, Issue:8 Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Edema; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Pyrazines; Quinoxalines; Rats; Rats, Wistar	2004
A novel synthesis of arylpyrrolo[1,2-a]pyrazinone derivatives. Molecules (Basel, Switzerland), 2004, Jun-30, Volume: 9, Issue:7 Topics: Animals; Cyclization; Drug Evaluation, Preclinical; Edema; Male; Mice; Pyrazines; Pyrroles	2004
Clinical trial of a potassium-sparing saluretic pyrazine derivative (MK-870). Acta medica Scandinavica, 1967, Volume: 181, Issue:4 Topics: Adult; Aged; Carbon Dioxide; Chlorides; Creatine; Diuretics; Edema; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle Aged; Potassium; Pyrazines; Sodium; Uric Acid	1967
Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Animals; Calmodulin; Cardiotonic Agents; Dermatitis; Edema; Eosinophils; Female; Guinea Pigs; In Vitro Techniques; Indium Radioisotopes; Isoenzymes; Male; Neutrophils; Passive Cutaneous Anaphylaxis; Phosphodiesterase Inhibitors; Purinones; Pyrazines; Pyrrolidinones; Rolipram; Skin	1994
Aminopyrazinyl derivatives: synthesis and evaluation of antiinflammatory and related activities. Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Edema; Female; Indomethacin; Lethal Dose 50; Male; Mice; Pain Measurement; Phenylbutazone; Pyrazines; Rats; Rats, Wistar; Reaction Time; Stomach Ulcer	1994
[Spirolactones and potassium-sparing diuretics]. La Revue du praticien, 1978, Nov-11, Volume: 28, Issue:51 Topics: Amiloride; Edema; Humans; Hyperaldosteronism; Hypertension; Pyrazines; Spironolactone; Triamterene	1978
[Treatment of oedematous conditions in combining amilorid and hydrochlorothiazid (author's transl)]. Bratislavske lekarske listy, 1976, Volume: 66, Issue:3 Topics: Amiloride; Drug Therapy, Combination; Edema; Humans; Hydrochlorothiazide; Pyrazines	1976
[Use of amiloride in diuretic treatment (author's transl)]. Bratislavske lekarske listy, 1975, Volume: 64, Issue:5 Topics: Amiloride; Diuresis; Edema; Glomerular Filtration Rate; Humans; Pyrazines	1975
Research on heterocyclic compounds, XXIX. Synthesis and antiinflammatory activity of imidazo[1,2-a]pyrazine derivatives. Farmaco (Societa chimica italiana : 1989), 1992, Volume: 47, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Pyrazines; Rats	1992
[Clinical study of amiloride hydrochloride, a diuretic with low potassium loss]. La Presse medicale, 1970, Jan-03, Volume: 78, Issue:1 Topics: Arrhythmias, Cardiac; Blood Urea Nitrogen; Cardiac Complexes, Premature; Diuretics; Drug Synergism; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrhosis; Potassium; Pyrazines; Sodium	1970
[Treatment of the edemato-ascitic syndrome in cirrhotics, role of amiloride (MK870)]. Bordeaux medical, 1972, Volume: 5, Issue:16 Topics: Adult; Aged; Amiloride; Ascites; Diuretics; Edema; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Pyrazines	1972
[Clinical study of the anti-inflammatory agent: carudol]. Revue d'odonto-stomatologie du midi de la France, 1972, Volume: 30, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Cellulitis; Edema; Female; Humans; Jaw Fractures; Joint Diseases; Male; Middle Aged; Osteitis; Pain; Postoperative Care; Preoperative Care; Prognosis; Pyrazines; Surgery, Plastic; Temporomandibular Joint; Tooth Extraction	1972
Effect of amiloride hydrochloride (MK-870) in patients with cirrhosis. The Johns Hopkins medical journal, 1969, Volume: 125, Issue:2 Topics: Diuretics; Edema; Humans; Hypokalemia; Kidney Failure, Chronic; Liver Cirrhosis; Natriuresis; Potassium; Pyrazines	1969