Page last updated: 2024-08-21

pyrazines and Ebola Hemorrhagic Fever

pyrazines has been researched along with Ebola Hemorrhagic Fever in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	44 (89.80)	24.3611
2020's	5 (10.20)	2.80

Authors

Authors	Studies
Barron, S; Barrot, L; Carbonnelle, C; de Lamballerie, X; Duthey, A; Guedj, J; Jacquot, F; Lacarelle, B; Madelain, V; Mentré, F; Mundweiler, S; Raoul, H; Solas, C; Thomas, D; Vallvé, A	1
Anglaret, X; Baize, S; de Lamballerie, X; Graw, F; Guedj, J; Günther, S; Laouénan, C; Madelain, V; Malvy, D; Mentré, F; Nguyen, THT; Oestereich, L; Piorkowski, G; Raoul, H	1
Baillet, N; Baize, S; de Lamballerie, X; Gloaguen, E; Guedj, J; Madelain, V; Mullaert, J; Raoul, H; Reynard, S	1
Aliota, MT; Bonnac, LF; Geraghty, RJ	1
Brasel, T; Comer, JE; Escaffre, O; Freiberg, AN; Ikegami, T; Juelich, TL; Kalveram, B; Massey, S; Neef, N; Perez, D; Smith, J; Smith, JK; Zhang, L	1
Ji, J; Liu, X; Tian, Y; Zhai, M; Zhang, J; Zhang, T	1
Anglaret, X; Antierens, A; Beavogui, AH; Berbain, E; Camara, AM; Carazo Perez, S; Depoortere, E; Folkesson, E; Lefevre, A; Maes, P; Malme, KN; Malvy, JD; Ombelet, S; Piguet, P; Poelaert, G; Sissoko, D; Tounkara, A; Trbovic, P	1
Biava, G; Brucato, A; Ippolito, G; Nicastri, E; Petrosillo, N; Uyeki, TM	1
Biava, G; Chinello, P; Ippolito, G; Nicastri, E; Petrosillo, N; Pittalis, S	1
Bavari, S; Bixler, SL; Bocan, TM; Cazares, LH; Donnelly, G; Epstein, C; Garza, NL; Giesing, D; Lenk, R; Liang, LF; Soloveva, V; Van Tongeren, SA; Warren, TK; Welch, L; Wells, J; Wetzel, KS	1
Bavari, S; Bixler, SL; Bocan, TM; Cazares, LH; Dong, L; Donnelly, G; Epstein, C; Garza, NL; Giesing, D; Koistinen, KA; Lenk, R; Liang, LF; Nuss, J; Soloveva, V; Van Tongeren, SA; Warren, TK; Welch, L; Wells, J; Wetzel, KS	1
Caluwaerts, S	1
Carbonnelle, C; de Lamballerie, X; Guedj, J; Gunther, S; Jacquot, F; Madelain, V; Mentré, F; Nguyen, THT; Piorkowski, G; Raoul, H; Rodallec, A	1
Check Hayden, E	1
Baize, S; Barron, S; Carbonnelle, C; de Lamballerie, X; Fizet, A; Guedj, J; Jacquot, F; Lacarelle, B; Madelain, V; Mentré, F; Raoul, H; Reynard, S; Solas, C	1
Brasel, T; Comer, JE; Escaffre, O; Freiberg, AN; Juelich, TL; Kalveram, B; Massey, S; Neef, N; Perez, DD; Smith, J; Smith, JK; Zhang, L	1
Afrough, B; Akoi Bore, J; Anglaret, X; Arnold, U; Bah, A; Baum, JHJ; Beavogui, AH; Becker-Ziaja, B; Bockholt, S; Böttcher, JP; Cabeza-Cabrerizo, M; Camara, AM; Camino, A; Carroll, MW; Carter, L; Castro, CM; Cisse, SD; Colin, G; Cowley, LA; Di Caro, A; Diallo, B; Drury, P; Duraffour, S; Enkirch, T; Fleischmann, E; Formenty, P; Gabriel, M; Garcia-Dorival, I; Ghebreghiorghis, L; Günther, S; Gurry, C; Hetzelt, N; Hinzmann, J; Holm, T; Hugh Logue, C; Ippolito, G; Jaeger, A; Juchet, S; Kafetzopoulou, L; Keita, S; Kerber, R; Koivogui, L; Kolie, JS; Kosgei, A; Krumkamp, R; Kuisma, E; Lorenz, E; Magassouba, N; Malvy, D; Marchal, CL; May, J; Mazzarelli, A; Meisel, S; Mertens, M; Michel, J; Miranda, O; Nitzsche, K; Pallasch, E; Patrono, LV; Portmann, J; Raymond Koundouno, F; Repits, J; Rickett, NY; Rudolf, M; Sachse, A; Singethan, K; Sissoko, D; Stoecker, K; Vitoriano, I; Wölfel, R; Wurr, S; Yenamaberhan, RL; Zekeng, EG	1
Adhikari, NKJ; Bah, EI; Chan, A; Fowler, RA; Hajek, J; Kao, R; Kiiza, P; Kwon, HY; Lamah, MC; Lamontagne, F; Lee, JS; Mishra, S; Murthy, S; Siemieniuk, R; Teo, K	1
Bavari, S; Chitty, AJ; Espy, N; Garcia, K; Nagle, E; Palacios, G; Pfeffer, B; Sanchez-Lockhart, M; Warren, T; Wiley, M	1
Eastaugh, LS; Lenk, RP; Lever, MS; Nelson, M; Smither, SJ; Steward, JA	1
Günther, S; Lüdtke, A; Muñoz-Fontela, C; Oestereich, L; Rieger, T; Wurr, S	1
Gulland, A	1
Anglaret, X; de Lamballerie, X; Guedj, J; Keïta, S; Malvy, D; Mentré, F; Taburet, AM	1
Mohammadi, D	1
Becker, S; Brodt, HR; de Leuw, P; Grünewald, T; Kann, G; Kempf, VA; Keppler, OT; Stephan, C; Vogl, T; Wolf, T; Zacharowski, K	1
Hasegawa, M; Ishii, M; Lefor, AK; Nagata, T	1
Nau, JY	2
Boyles, T	1
Cohen, J; Kupferschmidt, K	1
Anglaret, X; Bouazza, N; de Lamballerie, X; Foissac, F; Frange, P; Guedj, J; Keïta, S; Malvy, D; Mentré, F; Taburet, AM; Treluyer, JM	1
Bavari, S; Cardile, AP; Mayers, DL	1
Arnalich, F; Arribas, JR; Arsuaga, M; Borobia, AM; Carcas, AJ; de la Calle, F; Fernández-Puntero, B; Figueira, JC; Flores, E; García-de-Lorenzo, A; Jiménez-Yuste, V; Lago, M; Lasala, F; Mora-Rillo, M; Negredo, A; Nuñez, C; Ramírez-Olivencia, G; Sánchez-Seco, P; Viejo, A	1
Declerck, H; Decroo, T; Van Herp, M	1
Chappuis, F; Cherpillod, P; Cordey, S; Dayer, JA; Docquier, M; Gasche, Y; Iten, A; Kaiser, L; Petty, TJ; Pittet, D; Pugin, J; Rees, PSC; Samii, K; Sarria, FB; Schibler, M; Siegrist, CA; Simpson, AJH; Vetter, P; Vieille, G; Yerly, S; Zdobnov, EM	1
Blondiaux, J; Haque, A; Hober, D	1
de Lamballerie, X; Graw, F; Guedj, J; Günther, S; Madelain, V; Mentré, F; Nguyen, TH; Oestereich, L	1
Antonini, M; Capobianchi, MR; Di Caro, A; Ippolito, G; Kobinger, GP; Lanini, S; Lauria, FN; Magrini, N; Nicastri, E; Petrosillo, N; Puro, V; Shindo, N	1
Bailey, KW; Bray, M; Dagley, A; Downs, B; Furuta, Y; Gowen, BB; Jung, KH; Sefing, EJ; Smee, DF; Van Wettere, AJ; Wandersee, L; Westover, JB	1
de Lamballerie, X; Guedj, J; Madelain, V; Mentré, F; Nguyen, TH; Olivo, A; Taburet, AM	1
Allaford Duverger, T; Anglaret, X; Antierrens, A; Arnould, I; Augier, A; Badir, J; Baize, S; Bangoura, N; Barbe, S; Baret, G; Barry, TS; Barte de Sainte Fare, E; Beavogui, AH; Bentahir, M; Berbain, E; Berette, S; Berutto, C; Bocquin, A; Bongono, A; Bore, JA; Camara, AM; Camara, D; Camara, FS; Camara, MS; Carazo, S; Carbonnelle, C; Carmoi, T; Carroll, M; Chanfreau Munoz, V; Colin, G; Colpaert, J; Conde, MN; D'Ortenzio, E; Danel, C; de Lamballerie, X; Deccache, Y; Defourny, I; Delamou, L; Di Caro, A; Diederich, S; Dindart, JM; Dortenzio, E; Doumbouya, L; Draguez, B; Dumont, C; Duraffour, S; Durant, JF; Eholie, SP; El Bakkouri, K; Etienne, A; Ezzedine, K; Fizet, A; Folkesson, E; Frange, P; Gabriel, M; Gala, JL; Gasasira Uwamahoro, M; Gonzalez, MC; Guedj, J; Günther, S; Gustin, L; Hinzmann, J; Irenge, L; Jansson, L; Keïta, S; Kerber, R; Kighoma, PM; Kolie, J; Komano, MS; Koundouno, FR; Kourouma, E; Kraus, A; Kuisma, E; Lamah, MC; Laouenan, C; Le Marcis, F; Lefevre, A; Leno, T; Levy-Marchal, C; Liedigk, B; Loua, CM; Loua, M; M'Lebing, AB; Maes, P; Malme, K; Malvy, D; Manfrin, E; Maomou, A; Massala, V; Mely, S; Mentre, F; Milinouno, A; Moh, R; Moumouni, K; Murgue, B; Ngabo, D; Nguyen, VK; Ombelet, S; Palich, R; Pannetier, D; Petitjean, F; Peyrouset, O; Piguet, P; Pizarro, L; Poelart, G; Poncin, M; Provost, C; Raoul, H; Rapp, C; Rudolf, M; Samake, N; Savini, H; Sekou, C; Shepherd, S; Sidiboun, AY; Sissoko, D; Smits, B; Soumah, A; Taburet, AM; Thom, R; Toufik, N; Tounkara, A; Tran-Minh, T; Treluyer, JM; Van Cauwenberghe, S; Van Herp, M; Verreckt, I; Wölfel, R; Yazdanpanah, Y; Yombouno, P	1
Abdoul, BM; Anglaret, X; Augier, A; Blackwell, N; Danel, C; Gala, JL; Kinda, M; Malvy, D; Palich, R; Petitjean, F; Peyrouset, O; Shepherd, S	1
Balestra, P; Capobianchi, MR; Di Caro, A; Giancola, ML; Ippolito, G; Nicastri, E; Petrosillo, N; Ricottini, M	1
Bai, CQ; Cao, YX; Chen, YS; Dafae, F; Deng, YQ; Gao, GF; Hu, Y; Jiang, JF; Kanu, A; Kargbo, B; Kargbo, D; Liu, L; Liu, WS; Liu, WW; Liu, ZY; Lu, HJ; Mu, JS; Nie, WM; Niu, WK; Qian, J; Song, YB; Su, HX; Sun, Y; Tong, YG; Wang, CY; Wang, H; Wang, HQ; Wang, YP; Yan, T; Yang, F; Zhang, XG	1
Kraft, CS	1
Carlson, RD; Crozier, I; Debiec, MR; Hill, CE; Kraft, CS; Kumar, G; Lyon, GM; Martin, DF; Mehta, AK; Nussenblatt, RB; Olsen, TW; Patel, PS; Ribner, BS; Shantha, JG; Smith, JR; Ströher, U; Uyeki, TM; Varkey, JB; Yeh, S	1
Delaune, D; Dufour-Gaume, F; Martinaud, C; Sailliol, A	1
Beigel, J; Davey, RT; Dodd, L; Fauci, AS; Koopmeiners, JS; Lane, HC; Malvy, D; Massaquoi, MBF; Neaton, J; Neuhaus Nordwall, J; Proschan, MA; Sahr, F; Tierney, J	1
Anglaret, X; Baize, S; Bore, JA; Carazo, S; Carbonnelle, C; Conde, MN; de Lamballerie, X; Gala, JL; Guedj, J; Jacquot, F; Laouénan, C; Madelain, V; Malvy, D; Mentré, F; Nguyen, TH; Pastorino, B; Piorkowski, G; Raoul, H; Rodallec, A; Sissoko, D; Taburet, AM	1

Reviews

7 review(s) available for pyrazines and Ebola Hemorrhagic Fever

Article	Year
Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials. CPT: pharmacometrics & systems pharmacology, 2020, Volume: 9, Issue:5 Topics: Amides; Animals; Antiviral Agents; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Hemorrhagic Fever, Ebola; Humans; Models, Theoretical; Pyrazines	2020
Broad-Spectrum Antiviral Strategies and Nucleoside Analogues. Viruses, 2021, 04-13, Volume: 13, Issue:4 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; COVID-19 Drug Treatment; Hemorrhagic Fever, Ebola; Humans; Middle East Respiratory Syndrome Coronavirus; Mutagenesis; Nucleosides; Pyrazines; Ribavirin; SARS-CoV-2; Virus Replication; Zika Virus; Zika Virus Infection	2021
Anti-Ebola therapy for patients with Ebola virus disease: a systematic review. BMC infectious diseases, 2019, May-02, Volume: 19, Issue:1 Topics: Amides; Amodiaquine; Antibodies, Monoclonal; Antiviral Agents; Artemisinins; Databases, Factual; Drug Combinations; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Pyrazines; Randomized Controlled Trials as Topic	2019
Current status of chemically synthesized inhibitors of Ebola virus. Recent patents on anti-infective drug discovery, 2014, Volume: 9, Issue:2 Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cytosine; Drug Discovery; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Patents as Topic; Purine Nucleosides; Pyrazines; Pyrrolidines	2014
Acute respiratory distress syndrome after convalescent plasma use: treatment of a patient with Ebola virus disease contracted in Madrid, Spain. The Lancet. Respiratory medicine, 2015, Volume: 3, Issue:7 Topics: Acute Lung Injury; Adult; Amides; Antiviral Agents; Female; Hemorrhagic Fever, Ebola; Humans; Nursing Assistants; Occupational Diseases; Patient Isolation; Plasma; Pyrazines; Respiratory Distress Syndrome; Spain; Superinfection; Transfusion Reaction; Viral Load	2015
Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Amides; Amidines; Androstenes; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antiviral Agents; Benzofurans; Cytosine; Disease Models, Animal; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Immune Sera; Organophosphonates; Pyrazines; RNA, Small Interfering; Stilbenes; Virus Replication	2015
Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials. Clinical pharmacokinetics, 2016, Volume: 55, Issue:8 Topics: Adenine; Adenosine; Amides; Animals; Antiviral Agents; Disease Outbreaks; Ebolavirus; Healthy Volunteers; Hemorrhagic Fever, Ebola; Humans; Models, Animal; Purine Nucleosides; Pyrazines; Pyrrolidines	2016

Trials

3 trial(s) available for pyrazines and Ebola Hemorrhagic Fever

Article	Year
Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea. PLoS medicine, 2016, Volume: 13, Issue:3 Topics: Adolescent; Adult; Amides; Antiviral Agents; Child; Child, Preschool; Ebolavirus; Feasibility Studies; Female; Guinea; Hemorrhagic Fever, Ebola; Historically Controlled Study; Humans; Infant; Male; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Therapies, Investigational; Treatment Outcome; Viral Load; Young Adult	2016
A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection. The New England journal of medicine, 2016, 10-13, Volume: 375, Issue:15 Topics: Adolescent; Adult; Africa, Western; Amides; Antibodies, Monoclonal; Bayes Theorem; Child; Combined Modality Therapy; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Humans; Kaplan-Meier Estimate; Male; Polymerase Chain Reaction; Pyrazines; Treatment Outcome; United States; Viral Load	2016
Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted. PLoS neglected tropical diseases, 2017, Volume: 11, Issue:2 Topics: Adolescent; Adult; Aged; Amides; Antiviral Agents; Child; Child, Preschool; Ebolavirus; Female; Guinea; Hemorrhagic Fever, Ebola; Humans; Male; Middle Aged; Pyrazines; Young Adult	2017

Other Studies

39 other study(ies) available for pyrazines and Ebola Hemorrhagic Fever

Article	Year
Ribavirin does not potentiate favipiravir antiviral activity against Ebola virus in non-human primates. Antiviral research, 2020, Volume: 177 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Macaca fascicularis; Pyrazines; Ribavirin; Viral Load; Virus Replication	2020
Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates. PLoS neglected tropical diseases, 2021, Volume: 15, Issue:3 Topics: Amides; Animals; Antiviral Agents; Cytokine Release Syndrome; Cytokines; Disease Models, Animal; Ebolavirus; Hemorrhagic Fever, Ebola; Macaca fascicularis; Pyrazines; T-Lymphocytes; Viral Load; Viremia; Virus Replication	2021
STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV). Viruses, 2021, 07-17, Volume: 13, Issue:7 Topics: Amides; Animals; Antibodies, Viral; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Male; Mice; Mice, Knockout; Pyrazines; STAT1 Transcription Factor; Viral Proteins	2021
Recent progress on the treatment of Ebola virus disease with Favipiravir and other related strategies. Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11 Topics: Amides; Animals; Antiviral Agents; Hemorrhagic Fever, Ebola; Humans; Mice; Pyrazines	2017
Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa. PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6 Topics: Amides; Antiviral Agents; Clinical Trials as Topic; Confidentiality; Disease Outbreaks; Guinea; Hemorrhagic Fever, Ebola; Humans; Informed Consent; Medical Records; Pyrazines; Research Design	2017
Acute rhabdomyolysis and delayed pericardial effusion in an Italian patient with Ebola virus disease: a case report. BMC infectious diseases, 2017, 08-30, Volume: 17, Issue:1 Topics: Adrenal Cortex Hormones; Adult; Amides; Antibodies, Monoclonal; Ebolavirus; Health Personnel; Hemorrhagic Fever, Ebola; Humans; Indomethacin; Italy; Male; Pericardial Effusion; Pyrazines; Rhabdomyolysis; Sierra Leone	2017
QTc interval prolongation during favipiravir therapy in an Ebolavirus-infected patient. PLoS neglected tropical diseases, 2017, Volume: 11, Issue:12 Topics: Adult; Amides; Antiviral Agents; Arrhythmias, Cardiac; Ebolavirus; Electrocardiography; Hemorrhagic Fever, Ebola; Humans; Italy; Levofloxacin; Male; Pyrazines; RNA-Dependent RNA Polymerase; Virus Replication	2017
Intracellular conversion and in vivo dose response of favipiravir (T-705) in rodents infected with Ebola virus. Antiviral research, 2018, Volume: 151 Topics: Amides; Animals; Antiviral Agents; Cell Line; Cell Survival; Cytoplasm; Disease Models, Animal; Dose-Response Relationship, Drug; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Marburgvirus; Mice, Inbred C57BL; Pyrazines; Survival Analysis; Virus Replication	2018
Efficacy of favipiravir (T-705) in nonhuman primates infected with Ebola virus or Marburg virus. Antiviral research, 2018, Volume: 151 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Male; Marburg Virus Disease; Marburgvirus; Primates; Pyrazines; RNA, Viral; Survival Analysis; Viral Load	2018
Nubia's mother: being pregnant in the time of experimental vaccines and therapeutics for Ebola. Reproductive health, 2017, Dec-14, Volume: 14, Issue:Suppl 3 Topics: Africa, Western; Amides; Antibodies, Monoclonal; Antiviral Agents; Ebola Vaccines; Female; Guinea; Health Services Accessibility; Hemorrhagic Fever, Ebola; Humans; Pregnancy; Pregnancy Complications, Infectious; Pyrazines; Randomized Controlled Trials as Topic	2017
Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques. PLoS medicine, 2018, Volume: 15, Issue:3 Topics: Amides; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Ebolavirus; Female; Genome, Viral; Hemorrhagic Fever, Ebola; Humans; Macaca fascicularis; Mutagenesis; Pyrazines; RNA; Time Factors; Translational Research, Biomedical; Viral Load	2018
Experimental drugs poised for use in Ebola outbreak. Nature, 2018, Volume: 557, Issue:7706 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal; Congo; Disease Outbreaks; Drugs, Investigational; Ebola Vaccines; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Internationality; Pyrazines; Ribonucleotides	2018
Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies. Nature communications, 2018, 10-01, Volume: 9, Issue:1 Topics: Amides; Animals; Antiviral Agents; Cytokines; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Host-Pathogen Interactions; Interferon-alpha; Macaca; Models, Theoretical; Pyrazines; Survival Analysis; Time Factors; Viral Load	2018
Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir. Viruses, 2019, 02-03, Volume: 11, Issue:2 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Filoviridae; Filoviridae Infections; Gene Knockout Techniques; Hemorrhagic Fever, Ebola; Liver; Male; Marburg Virus Disease; Marburgvirus; Mice; Mice, Knockout; Proof of Concept Study; Pyrazines; Receptors, Interferon; RNA, Viral; Spleen; Virulence	2019
Laboratory Findings, Compassionate Use of Favipiravir, and Outcome in Patients With Ebola Virus Disease, Guinea, 2015-A Retrospective Observational Study. The Journal of infectious diseases, 2019, 06-19, Volume: 220, Issue:2 Topics: Adolescent; Adult; Amides; Antiviral Agents; Child; Child, Preschool; Compassionate Use Trials; Ebolavirus; Female; Guinea; Hemorrhagic Fever, Ebola; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pyrazines; Retrospective Studies; Viral Load; Young Adult	2019
T-705 induces lethal mutagenesis in Ebola and Marburg populations in macaques. Antiviral research, 2019, Volume: 170 Topics: Amides; Animals; Antiviral Agents; DNA, Viral; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Macaca; Male; Marburg Virus Disease; Marburgvirus; Mutagenesis; Pyrazines; Viremia	2019
Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antiviral research, 2014, Volume: 104 Topics: Administration, Oral; Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Hemorrhagic Fever, Ebola; Mice; Mice, Knockout; Pyrazines	2014
Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model. Antiviral research, 2014, Volume: 105 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Hemorrhagic Fever, Ebola; Mice, Inbred C57BL; Mice, Knockout; Pyrazines; Survival Analysis; Viral Load; Virus Replication	2014
Clinical trials of Ebola therapies to begin in December. BMJ (Clinical research ed.), 2014, Nov-14, Volume: 349 Topics: Adult; Amides; Blood Transfusion; Child; Clinical Trials as Topic; Guinea; Hemorrhagic Fever, Ebola; Humans; Pyrazines	2014
Dose regimen of favipiravir for Ebola virus disease. The Lancet. Infectious diseases, 2015, Volume: 15, Issue:2 Topics: Adult; Amides; Animals; Antiviral Agents; Computer Simulation; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Mice; Models, Animal; Plasma; Pyrazines	2015
First trials for Ebola treatments announced. Lancet (London, England), 2014, Nov-22, Volume: 384, Issue:9957 Topics: Africa, Western; Amides; Clinical Trials as Topic; Drug Approval; Drugs, Investigational; Female; Follow-Up Studies; Hemorrhagic Fever, Ebola; Humans; Male; Patient Selection; Pyrazines; Risk Assessment; Treatment Outcome	2014
Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care. Lancet (London, England), 2015, Apr-11, Volume: 385, Issue:9976 Topics: Adult; Amides; Amiodarone; Anti-Infective Agents; Antiviral Agents; Blood Vessels; Critical Care; Fibrin Fibrinogen Degradation Products; Hemorrhagic Fever, Ebola; Humans; Intubation, Intratracheal; Male; Multiple Organ Failure; Patient Isolation; Peptide Fragments; Pulmonary Edema; Pyrazines; Radiography, Thoracic; Renal Insufficiency; Respiratory Insufficiency	2015
Favipiravir: a new medication for the Ebola virus disease pandemic. Disaster medicine and public health preparedness, 2015, Volume: 9, Issue:1 Topics: Amides; Antiviral Agents; Disaster Planning; Drug Approval; Hemorrhagic Fever, Ebola; Humans; Japan; Pyrazines	2015
[Ebola: three experimental clinical trials directed by MSF]. Revue medicale suisse, 2014, Nov-26, Volume: 10, Issue:452 Topics: Africa, Western; Amides; Anti-Infective Agents; Clinical Trials as Topic; Cytosine; France; Health Services Accessibility; Hemorrhagic Fever, Ebola; Humans; International Cooperation; Organophosphonates; Pyrazines; Societies, Medical	2014
Priorities in Ebola research--a view from the field. Lancet (London, England), 2015, Jan-03, Volume: 385, Issue:9962 Topics: Amides; Clinical Trials as Topic; Female; Hemorrhagic Fever, Ebola; Humans; Male; Pyrazines	2015
Infectious diseases. Ebola drug trials lurch ahead. Science (New York, N.Y.), 2015, Feb-13, Volume: 347, Issue:6223 Topics: Amides; Antibodies, Monoclonal; Antiviral Agents; Clinical Trials as Topic; Cytosine; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Pyrazines	2015
Favipiravir for children with Ebola. Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968 Topics: Amides; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Dosage Calculations; Hemorrhagic Fever, Ebola; Humans; Infant; Pyrazines	2015
[Ebola and favipiravir: when political preempts scientific communication]. Revue medicale suisse, 2015, Mar-04, Volume: 11, Issue:464 Topics: Amides; Communication; Hemorrhagic Fever, Ebola; Humans; Politics; Pyrazines	2015
Favipiravir--a prophylactic treatment for Ebola contacts? Lancet (London, England), 2015, Jun-13, Volume: 385, Issue:9985 Topics: Amides; Antiviral Agents; Directly Observed Therapy; Hemorrhagic Fever, Ebola; Humans; Post-Exposure Prophylaxis; Pyrazines	2015
Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report. The Lancet. Infectious diseases, 2015, Volume: 15, Issue:9 Topics: Adult; Amides; Antiviral Agents; Ebolavirus; Genome, Viral; Half-Life; Hemorrhagic Fever, Ebola; Humans; Pyrazines; Viral Load; Virus Shedding	2015
Ebola virus dynamics in mice treated with favipiravir. Antiviral research, 2015, Volume: 123 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Mice, Inbred C57BL; Models, Theoretical; Pyrazines; Survival Analysis; Viral Load	2015
Ebola virus disease complicated with viral interstitial pneumonia: a case report. BMC infectious diseases, 2015, Oct-16, Volume: 15 Topics: Amides; Antibodies, Monoclonal; Antiviral Agents; Coinfection; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Lung Diseases, Interstitial; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Pyrazines; Respiration, Artificial; Respiratory Insufficiency; RNA, Viral; Viral Load	2015
Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses. Antiviral research, 2016, Volume: 126 Topics: Amides; Animals; Antiviral Agents; Arenavirus; Chlorocebus aethiops; Cricetinae; Dengue Virus; Disease Models, Animal; Drug Synergism; Female; Guinea Pigs; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, American; Hemorrhagic Fever, Ebola; Hemorrhagic Fevers, Viral; Junin virus; Male; Mesocricetus; Mice; Orthohantavirus; Pyrazines; Ribavirin; RNA Viruses; Vero Cells	2016
A 6-Year-Old Child with Severe Ebola Virus Disease: Laboratory-Guided Clinical Care in an Ebola Treatment Center in Guinea. PLoS neglected tropical diseases, 2016, Volume: 10, Issue:3 Topics: Amides; Antiviral Agents; Child; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Limit of Detection; Male; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Viral Load	2016
Temporary neurocognitive impairment with Ebola virus. Journal of neurology, neurosurgery, and psychiatry, 2016, Volume: 87, Issue:12 Topics: Adult; Amides; Cognitive Dysfunction; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Italy; Male; Middle Aged; Neuropsychological Tests; Pyrazines; Time Factors	2016
Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)-Sierra Leone, 2014. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Nov-15, Volume: 63, Issue:10 Topics: Adolescent; Adult; Amides; Antiviral Agents; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Humans; Kaplan-Meier Estimate; Male; Pyrazines; Retrospective Studies; Sierra Leone; Viral Load; Young Adult	2016
Editorial Commentary: Considerations of Favipiravir as a Medical Countermeasure in Future Randomized Controlled Trials Against Ebola Virus Disease. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, 11-15, Volume: 63, Issue:10 Topics: Amides; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Pyrazines; Randomized Controlled Trials as Topic; Sierra Leone	2016
Long-term Management of Panuveitis and Iris Heterochromia in an Ebola Survivor. Ophthalmology, 2016, Volume: 123, Issue:12 Topics: Administration, Oral; Adult; Amides; Atropine; Drug Combinations; Ebolavirus; Eye Infections, Viral; Fluprednisolone; Glucocorticoids; Hemorrhagic Fever, Ebola; Humans; Injections, Intraocular; Iris Diseases; Male; Microscopy, Acoustic; Multimodal Imaging; Mydriatics; Ophthalmic Solutions; Panuveitis; Pigmentation Disorders; Prednisone; Pyrazines; Real-Time Polymerase Chain Reaction; RNA, Viral; Survivors; Triamcinolone Acetonide; Vitreous Body	2016
Early and repeated use of plasma for the management of Ebola patients: Reflection around a case. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2017, Volume: 24, Issue:1 Topics: Amides; Anti-Bacterial Agents; Blood Component Transfusion; Blood Preservation; Combined Modality Therapy; Disease Management; Freeze Drying; Gastrointestinal Agents; Hemorrhagic Fever, Ebola; Humans; Male; Plasma; Pyrazines; Severity of Illness Index; Young Adult	2017