Page last updated: 2024-08-21

pyrazines and Diabetes Mellitus

pyrazines has been researched along with Diabetes Mellitus in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (38.46)	18.7374
1990's	3 (4.62)	18.2507
2000's	12 (18.46)	29.6817
2010's	23 (35.38)	24.3611
2020's	2 (3.08)	2.80

Authors

Authors	Studies
Begum, R; Garcia-Ocaña, A; Li, Y; Palit, SP; Parmar, N; Patel, R; Rathwa, N	1
Liu, H; Shi, Y; Xie, H; Zhou, Y	1
Barmade, MA; Bothara, KG; Miniyar, PB; Murumkar, PR; Patil, PS	1
Cohen, D	1
Fujimoto, M; He, P; Ishibashi, R; Ishikawa, T; Kawamura, H; Kobayashi, K; Okabe, E; Onishi, S; Takemoto, M; Watanabe, K; Yamaga, M; Yokote, K	1
Akay, A; Dragomir, A; Erlandsson, BE	1
Fathy, A; Khashab, S; Shaheen, N; Soliman, AR; Soliman, MA	1
Bussey, MR; Emanuele, MA; Lomasney, LM; Tehrani, R	1
Goto, C; Mizui, T; Ohta, H; Tachi, T; Teramachi, H; Toyoshima, M; Tsuchiya, T	1
Gallacher, DJ; Hemmeryckx, B; Roger Lijnen, H; Rong Lu, H; Swinnen, M	1
Åsberg, A; Hartmann, A; Jenssen, T; Strøm Halden, TA; Vik, K	1
Razzak, M	1
Aragonés, A; del Val, F; López, J; Luque, A; Sastre, J	1
Hegazy, SK	1
Namba, M	1
Yanai, H	2
Chao, TF; Chen, SJ; Chen, TJ; Chiang, CE; Huang, CM; Lin, SJ; Liu, CJ; Wang, KL; Wu, CH; Yeh, CM	1
Bril, V; Kuromiya, A; Kurono, M; Matsumoto, T; Nakamura, K; Ono, Y	1
De Meester, I; Lambeir, AM; Scharpé, S	1
Ahn, JH; Bae, MA; Cheon, HG; Jun, MA; Kang, NS; Kang, SK; Kim, KR; Kim, KY; Kim, SG; Kim, SS; Kim, SY; Lee, DH; Lee, JO; Park, WS; Rhee, SD; Shin, MS; Sohn, SK	1
Egan, JM; Kim, W	1
Miuchi, M; Miyagawa, J; Nanba, M	1
Resmi, H	1
Amo, K; Ito, Y; Koganei, M; Ohminami, H; Orime, K; Sasaki, H; Shirakawa, J; Tajima, K; Takeda, E; Terauchi, Y; Togashi, Y	1
Koelling, TM; Nemerovski, CW; Pinelli, NR	1
Collier, DS; Haire, CE; Lane, JT; Odegaard, DE; Stevens, RB; Wrenshall, LE	1
Daskiran, M; Dickson, WM; Kozma, CM; Nigam, S; Paris, A; Virdi, NS	1
Deldicque, L; Francaux, M; Raymackers, JM; van Loon, LJ; Zbinden-Foncea, H	1
Fujimoto, M; Ishibashi, R; Ishikawa, T; Kawamura, H; Kitamoto, T; Kobayashi, K; Okabe, E; Onishi, S; Takemoto, M; Yokote, K	1
Bjerve, KS; Grill, VE; Mostad, IL; Qvigstad, E	1
Bax, JJ; Bountioukos, MA; Elhendy, A; Krenning, EP; Poldermans, D; Roelandt, JR; Schinkel, AF; Valkema, R; van Domburg, RT; Vourvouri, EC	1
Singer, M	1
Giannoukakis, N	1
Mor, R; Pitlik, S; Rosenfeld, JB	1
Affrime, MB; Gould, A; Lowenthal, DT; Mazzella, J; Onesti, G; Shirk, J; Walker, F	1
Braatvedt, G; Corrall, RJ; Newrick, PG; Stansbie, D	1
Boden, G; Rocha, DM; Santomauro, AT; Santos, RF; Silva, ME; Strassmann, PG; Ursich, MJ; Wajchenberg, BL	1
Agius, L; Alberti, KG; Catalano, C; Fulcher, GR; Walker, M	1
De Baere, H; De Leeuw, I; Decraene, P; Lemmens, P; Verhaegen, H	1
Caputo, G; Emanueli, A; Molari, E; Pirola, LC	1
Alberti, KG; Aynsley-Green, A	1
Dulin, WE; Wyse, BM	1
Forattini, C	1
Angeli, G; Baraldi, B; Caputo, G; Tiraboschi, L	1
Castelletta, L; Ninni, M	1
Fagerberg, SE; Johannessen, A	1
Persson, G	1
Bommartini, F; Pedrazzi, F	1
Bossini, A; Lentini, S; Pirola, LC	1
D'Onofrio, F; Pempinello, R; Romis, L	1
Crepaldi, G; Emanueli, A; Fedele, D; Muggeo, M; Riva, F; Tiengo, A	1
Caputo, G; Montini, M; Pagani, G; Sacchetti, G; Vailati, G	1
Fuchs, K	1
Giudicelli, C; Masbernard, A; Massey, J	1
Cañadell Vidal, J	1
Caputo, G; Colucci, M; Ghionni, A; Iacono, G; Verde, G	1
Parodi, FA	1
Caputo, G; Montini, M; Pagani, G; Vailati, G	1
McNay, JL; Oran, E	1
Accietto, F; Fedeli, G; Fenici, R; Ghirlanda, G; Greco, AV; Lucente, M	1

Reviews

6 review(s) available for pyrazines and Diabetes Mellitus

Article	Year
Unequivocal role of pyrazine ring in medicinally important compounds: a review. Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:11 Topics: Antineoplastic Agents; Antitubercular Agents; Diabetes Mellitus; Diuretics; Humans; Hypoglycemic Agents; Kidney; Mycobacterium tuberculosis; Neoplasms; Protein Kinase Inhibitors; Pyrazines	2013
[Programs for continuing medical education: a session; 7. Recent trends in treatment of diabetes mellitus]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3 Topics: Acarbose; Biguanides; Blood Glucose Self-Monitoring; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Administration Routes; Drug Design; Drug Therapy, Combination; Education, Medical, Continuing; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Incretins; Insulin; Pyrazines; Sitagliptin Phosphate; Triazoles	2014
DPP4 inhibitors for diabetes--what next? Biochemical pharmacology, 2008, Dec-15, Volume: 76, Issue:12 Topics: Adamantane; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Hypoxia; Neoplasms; Nitriles; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin	2008
The role of incretins in glucose homeostasis and diabetes treatment. Pharmacological reviews, 2008, Volume: 60, Issue:4 Topics: Animals; Diabetes Mellitus; Exenatide; Glucose; Homeostasis; Humans; Hypoglycemic Agents; Incretins; Peptides; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms	2008
[Incretin related agents for treatment of diabetes mellitus]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2009, Apr-10, Volume: 98, Issue:4 Topics: Adamantane; Diabetes Mellitus; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Exenatide; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Incretins; Liraglutide; Nitriles; Peptides; Pyrazines; Pyrrolidines; Receptors, Glucagon; Sitagliptin Phosphate; Triazoles; Venoms; Vildagliptin	2009
Ranirestat as a therapeutic aldose reductase inhibitor for diabetic complications. Expert opinion on investigational drugs, 2008, Volume: 17, Issue:4 Topics: Aldehyde Reductase; Animals; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Enzyme Inhibitors; Humans; Pyrazines; Sorbitol; Spiro Compounds; Treatment Outcome	2008

Trials

16 trial(s) available for pyrazines and Diabetes Mellitus

Article	Year
Sitagliptin might be a favorable antiobesity drug for new onset diabetes after a renal transplant. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2013, Volume: 11, Issue:6 Topics: Adult; Anti-Obesity Agents; Blood Glucose; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin Glargine; Insulin, Long-Acting; Kidney Transplantation; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Weight Gain; Weight Loss	2013
Short-term efficacy and safety of sitagliptin treatment in long-term stable renal recipients with new-onset diabetes after transplantation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:4 Topics: Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Postprandial Period; Prospective Studies; Pyrazines; Risk Factors; Sitagliptin Phosphate; Time Factors; Treatment Outcome; Triazoles	2014
Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women. Journal of bone and mineral metabolism, 2015, Volume: 33, Issue:2 Topics: Absorptiometry, Photon; Aged; Alkaline Phosphatase; Amino Acids; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Lumbar Vertebrae; Metformin; Middle Aged; Osteocalcin; Osteogenesis; Osteoporosis, Postmenopausal; Postmenopause; Pyrazines; Sitagliptin Phosphate; Triazoles	2015
Contribution of nonesterified fatty acids to mitogen-activated protein kinase activation in human skeletal muscle during endurance exercise. International journal of sport nutrition and exercise metabolism, 2013, Volume: 23, Issue:3 Topics: Diabetes Mellitus; Exercise; Fatty Acids, Nonesterified; Humans; Hypolipidemic Agents; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Middle Aged; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Physical Endurance; Pyrazines; Sedentary Behavior; Young Adult	2013
Effect of diabetes mellitus on myocardial 18F-FDG SPECT using acipimox for the assessment of myocardial viability. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:6 Topics: Blood Glucose; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Feasibility Studies; Female; Fluorodeoxyglucose F18; Heart Ventricles; Humans; Male; Middle Aged; Pyrazines; Radionuclide Imaging; Radiopharmaceuticals; Ventricular Dysfunction, Left	2003
Suppression of lipolysis in normal man does not inhibit recovery from insulin-induced hypoglycaemia. European journal of clinical investigation, 1993, Volume: 23, Issue:1 Topics: Acetoacetates; Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Hyperlipidemias; Hypoglycemia; Hypolipidemic Agents; Insulin; Lipolysis; Male; Pyrazines	1993
Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes, 1999, Volume: 48, Issue:9 Topics: Adult; Basal Metabolism; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypolipidemic Agents; Insulin Resistance; Male; Obesity; Oxidation-Reduction; Pyrazines	1999
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. Diabetes, 1992, Volume: 41, Issue:11 Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glycerol; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Male; Middle Aged; Obesity; Pyrazines; Pyruvates; Triglycerides	1992
Glipizide, a new sulfonylurea in the treatment of diabetes mellitus. Summary of clinical experience in 1064 cases. Arzneimittel-Forschung, 1972, Volume: 22, Issue:11 Topics: Administration, Oral; Adult; Aged; Blood Cell Count; Blood Glucose; Blood Proteins; Cholesterol; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Drug Eruptions; Female; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Nausea; Prothrombin Time; Pyrazines; Sulfonylurea Compounds; Tolbutamide; Transaminases; Vomiting	1972
[Clinical experimentation with a new hypoglycemic agent (glipizide)]. Minerva medica, 1972, Oct-06, Volume: 63, Issue:70 Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Drug Tolerance; Evaluation Studies as Topic; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1972
[New oral hypoglycemic agent: K 4024 or glipizide. Clinical trial]. La Clinica terapeutica, 1972, Dec-15, Volume: 63, Issue:5 Topics: Adult; Aged; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Evaluation Studies as Topic; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1972
[Evaluation of a new sulfonylurea, glipizide, in the treatment of diabetes mellitus]. Minerva medica, 1973, Oct-10, Volume: 64, Issue:71 Topics: Adult; Aged; Biguanides; Blood Glucose; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Drug Evaluation; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1973
Glipizide, a new oral antidiabetic agent (report of a controlled clinical study in Sweden). Diabetologia, 1973 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; Cholesterol; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Diet, Diabetic; Drug Evaluation; Female; Glycosuria; Humans; Hypoglycemic Agents; Male; Middle Aged; Placebos; Potassium; Pyrazines; Sodium; Sulfonylurea Compounds; Sweden; Time Factors	1973
Clinical study with glipizide, a new oral antidiabetic drug. Diabetologia, 1973 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Cholesterol; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus; Diet, Diabetic; Drug Evaluation; Electrolytes; Female; Glycosuria; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenformin; Placebos; Pyrazines; Sulfonylurea Compounds	1973
A controlled clinical trial of a new oral hypoglycemic agent, glipizide (K 4024). Arzneimittel-Forschung, 1972, Volume: 22, Issue:7 Topics: Acetone; Adult; Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Drug Resistance; Female; Glycosuria; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds; Tolbutamide	1972
Effect of glipizide on a double-meal test in diabetic patients. Arzneimittel-Forschung, 1972, Volume: 22, Issue:11 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Dietary Carbohydrates; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Placebos; Pyrazines; Sulfonylurea Compounds; Time Factors	1972

Other Studies

43 other study(ies) available for pyrazines and Diabetes Mellitus

Article	Year
A novel therapeutic combination of sitagliptin and melatonin regenerates pancreatic β-cells in mouse and human islets. Biochimica et biophysica acta. Molecular cell research, 2022, Volume: 1869, Issue:8 Topics: Animals; Blood Glucose; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Humans; Hypoglycemic Agents; Melatonin; Mice; Pyrazines; Sitagliptin Phosphate; Triazoles	2022
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α. Molecular biology reports, 2022, Volume: 49, Issue:10 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Diabetes Mellitus; Diabetic Nephropathies; Endocytosis; Endoplasmic Reticulum Stress; Endoribonucleases; Epithelial Cells; Fluorescein-5-isothiocyanate; Glucose; Imidazoles; Low Density Lipoprotein Receptor-Related Protein-2; Membrane Proteins; Mice; Naphthalenes; Protein Serine-Threonine Kinases; Pyrazines	2022
Reports of pancreatitis are 20-30 times more likely with GLP-1 drugs, analysis finds. BMJ (Clinical research ed.), 2013, Apr-23, Volume: 346 Topics: Adamantane; Diabetes Mellitus; Dipeptides; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Linagliptin; Pancreatitis; Purines; Pyrazines; Quinazolines; Sitagliptin Phosphate; Triazoles; United States	2013
Sitagliptin improves postprandial hyperglycemia by inhibiting glucagon secretion in Werner syndrome with diabetes. Diabetes care, 2013, Volume: 36, Issue:8 Topics: Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles; Werner Syndrome	2013
A novel data-mining platform leveraging social media to monitor outcomes of Januvia. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2013, Volume: 2013 Topics: Data Mining; Diabetes Mellitus; Humans; Hypoglycemic Agents; Pyrazines; Sitagliptin Phosphate; Social Media; Treatment Outcome; Triazoles	2013
Sitagliptin-induced bilateral Achilles tendinitis. Rheumatology (Oxford, England), 2014, Volume: 53, Issue:4 Topics: Achilles Tendon; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Magnetic Resonance Imaging; Middle Aged; Pyrazines; Sitagliptin Phosphate; Tendinopathy; Triazoles	2014
Pharmacoeconomic analysis of DPP-4 inhibitors. Die Pharmazie, 2013, Volume: 68, Issue:11 Topics: Adamantane; Clinical Trials as Topic; Cohort Studies; Cost-Benefit Analysis; Costs and Cost Analysis; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Nitriles; Piperidines; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Uracil; Vildagliptin	2013
Effect of sitagliptin treatment on metabolism and cardiac function in genetic diabetic mice. European journal of pharmacology, 2014, Jan-15, Volume: 723 Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Heart; Heart Function Tests; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; Pyrazines; Sitagliptin Phosphate; Triazoles	2014
Transplantation: sitagliptin-balancing cardiovascular risk, hyperglycaemia and safety. Nature reviews. Nephrology, 2014, Volume: 10, Issue:4 Topics: Diabetes Mellitus; Female; Humans; Kidney Transplantation; Male; Pyrazines; Triazoles	2014
Long-term efficacy of glibenclamide and sitagliptin therapy in adult patients with KCNJ11 permanent diabetes. Diabetes care, 2014, Volume: 37, Issue:3 Topics: Adolescent; Adult; Diabetes Mellitus; DNA; DNA Mutational Analysis; Female; Follow-Up Studies; Glucagon-Like Peptide 1; Glyburide; Humans; Hypoglycemic Agents; Mutation; Potassium Channels, Inwardly Rectifying; Pyrazines; Sitagliptin Phosphate; Time Factors; Triazoles	2014
Dipeptidyl peptidase-4 inhibitor sitagliptin significantly reduced hepatitis C virus replication in a diabetic patient with chronic hepatitis C virus infection. Hepatobiliary & pancreatic diseases international : HBPD INT, 2014, Volume: 13, Issue:5 Topics: Diabetes Complications; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Female; Hepatitis C, Chronic; Humans; Pyrazines; Triazoles	2014
Sitagliptin and the risk of hospitalization for heart failure: a population-based study. International journal of cardiology, 2014, Nov-15, Volume: 177, Issue:1 Topics: Diabetes Mellitus; Female; Follow-Up Studies; Glucagon-Like Peptide 1; Heart Failure; Hospitalization; Humans; Hypoglycemic Agents; Male; Middle Aged; Morbidity; Population Surveillance; Propensity Score; Pyrazines; Retrospective Studies; Risk Assessment; Risk Factors; Sitagliptin Phosphate; Taiwan; Triazoles	2014
Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats. Journal of pharmacological sciences, 2008, Volume: 107, Issue:3 Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Diabetic Neuropathies; Enzyme Inhibitors; Male; Neural Conduction; Pyrazines; Rats; Rats, Wistar; Sorbitol; Spiro Compounds; Streptozocin	2008
Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors. Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24 Topics: Binding Sites; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Design; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Piperazine; Piperazines; Pyrazines; Sitagliptin Phosphate; Structure-Activity Relationship; Triazoles	2008
I read about a new drug for diabetes called Januvia. Should I be interested in it? Heart advisor, 2009, Volume: 12, Issue:1 Topics: Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Humans; Pyrazines; Sitagliptin Phosphate; Triazoles; Weight Gain	2009
Sitagliptin in treatment of diabetes complicated by chronic hepatitis C. Hepatobiliary & pancreatic diseases international : HBPD INT, 2010, Volume: 9, Issue:4 Topics: Blood Glucose; Comorbidity; Diabetes Complications; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Female; Hepatitis C, Chronic; Humans; Middle Aged; Pyrazines; Sitagliptin Phosphate; Treatment Outcome; Triazoles	2010
The combination of bortezomib and resveratrol may prevent muscle wasting in diabetes. Medical hypotheses, 2011, Volume: 76, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Boronic Acids; Bortezomib; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Inflammation; Models, Biological; Muscular Atrophy; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Rats; Resveratrol; Stilbenes	2011
Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. The Journal of biological chemistry, 2011, Jul-22, Volume: 286, Issue:29 Topics: Administration, Oral; Animals; Apoptosis; Arachidonic Acid; Diabetes Mellitus; Dietary Carbohydrates; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucokinase; Glucose; Haploinsufficiency; Insulin-Secreting Cells; Linoleic Acid; Male; Mice; Pyrazines; Receptors, Glucagon; Signal Transduction; Sitagliptin Phosphate; Sucrose; Triazoles	2011
Successful long-term use of sitagliptin for the treatment of new-onset diabetes mellitus after solid organ transplantation: a case report. Transplantation proceedings, 2011, Volume: 43, Issue:5 Topics: Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Humans; Male; Middle Aged; Organ Transplantation; Pyrazines; Sitagliptin Phosphate; Triazoles	2011
Sitagliptin therapy in kidney transplant recipients with new-onset diabetes after transplantation. Transplantation, 2011, Nov-27, Volume: 92, Issue:10 Topics: Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Kidney Transplantation; Male; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles	2011
Association between sitagliptin adherence and self-monitoring of blood glucose. Journal of diabetes science and technology, 2012, May-01, Volume: 6, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Blood Glucose Self-Monitoring; Child; Computer Simulation; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Logistic Models; Male; Medication Adherence; Metformin; Middle Aged; Odds Ratio; Predictive Value of Tests; Pyrazines; Risk Factors; Sitagliptin Phosphate; Time Factors; Treatment Outcome; Triazoles; United States; Young Adult	2012
Sitagliptin successfully ameliorates glycemic control in Werner syndrome with diabetes. Diabetes care, 2012, Volume: 35, Issue:12 Topics: Blood Glucose; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Female; Humans; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles; Werner Syndrome	2012
Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects. American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:1 Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Dietary Proteins; Energy Intake; Exercise; Fasting; Fatty Acids; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hyperglycemia; Hypertriglyceridemia; Insulin; Insulin Secretion; Male; Middle Aged; Obesity; Proinsulin; Pyrazines	2003
New medications help those with diabetes avoid heart trouble. Drugs mimic the body's natural insulin and glucose controls, but diet and exercise are still keys to controlling the disease. Heart advisor, 2007, Volume: 10, Issue:7 Topics: Diabetes Mellitus; Diabetic Angiopathies; Exenatide; Heart Diseases; Humans; Hypoglycemic Agents; Metformin; Peptides; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms	2007
Type 2 diabetes drug boom: is newer better? The Johns Hopkins medical letter health after 50, 2007, Volume: 19, Issue:6 Topics: Amyloid; Diabetes Mellitus; Exenatide; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Middle Aged; Peptides; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms	2007
Management of comorbid diabetes and cancer. Oncology (Williston Park, N.Y.), 2007, Volume: 21, Issue:8 Suppl Topics: Ambulatory Care; Amyloid; Comorbidity; Diabetes Mellitus; Exenatide; Humans; Hypoglycemic Agents; Inpatients; Insulin; Islet Amyloid Polypeptide; Neoplasms; Peptides; Practice Guidelines as Topic; Pyrazines; Quality of Life; Risk Factors; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Venoms	2007
Indomethacin- and Moduretic--induced hyperkalemia. Israel journal of medical sciences, 1983, Volume: 19, Issue:6 Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Pyrazines	1983
Effects of amiloride on oral glucose loading, serum potassium, renin, and aldosterone in diet-controlled diabetes. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5 Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diet, Diabetic; Glucose Tolerance Test; Humans; Hyperkalemia; Insulin; Posture; Potassium; Pyrazines; Renin; Triamterene	1980
[The connection between Moduretic and diabetes mellitus. A case report]. Lakartidningen, 1975, Jun-18, Volume: 72, Issue:25 Topics: Aged; Amiloride; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Pyrazines	1975
An open comparative study of the efficacy and tolerance of a new antidiabetic agent: glipizide. Diabetologia, 1973 Topics: Blood Glucose; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Nausea; Phenformin; Pyrazines; Sulfonylurea Compounds	1973
Diuretics and carbohydrate metabolism: the effects of furosemide and amiloride on blood glucose, plasma insulin and cations in the rat. Diabetologia, 1973, Volume: 9, Issue:1 Topics: Adrenalectomy; Amiloride; Animals; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus; Disease Models, Animal; Diuretics; Erythrocytes; Furosemide; Glucose Tolerance Test; Hyperkalemia; Insulin; Male; Potassium; Pyrazines; Rats; Sodium; Streptozocin	1973
Studies on the ability of compounds to block the diabetogenic activity of streptozotocin. Diabetes, 1969, Volume: 18, Issue:7 Topics: Amino Acids; Animals; Diabetes Mellitus; Diaphragm; Diazoxide; Epinephrine; Ethanol; Glucosamine; Glucose; Hyperglycemia; Hypoglycemic Agents; Male; NAD; Niacinamide; Nitroso Compounds; Pyrazinamide; Pyrazines; Pyrazoles; Rats; Tolbutamide	1969
[Clinical evaluation of glidiazinamide]. Giornale di gerontologia, 1972, Volume: 20, Issue:5 Topics: Blood Glucose; Cyclohexanes; Diabetes Mellitus; Evaluation Studies as Topic; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Pyrazines; Sulfonylurea Compounds	1972
Clinical and metabolic observations with a new synthetic oral antidiabetic agent, glipizide. Arzneimittel-Forschung, 1972, Volume: 22, Issue:11 Topics: Administration, Oral; Adult; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Fasting; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Pyrazines; Sulfonylurea Compounds; Time Factors	1972
Modifications of glycemia and insulinemia in diabetics treated with glipizide (K 4024), a new sulfonylurea. Arzneimittel-Forschung, 1972, Volume: 22, Issue:11 Topics: Administration, Oral; Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds; Time Factors	1972
Glipizide versus tolbutamide in maturity-onset diabetes, an open comparative study. Diabetologia, 1973 Topics: Administration, Oral; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Diet, Diabetic; Humans; Hypoglycemia; Hypoglycemic Agents; Pyrazines; Sulfonylurea Compounds; Tolbutamide	1973
Clinical experience with glipizide in the treatment of mostly complicated diabetes. Diabetologia, 1973 Topics: Administration, Oral; Adult; Aged; Blood Cell Count; Blood Glucose; Blood Urea Nitrogen; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Drug Evaluation; Female; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Lipids; Liver Function Tests; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1973
[Clinical trial of glypizide]. Revista iberica de endocrinologia, 1974, Volume: 21, Issue:121 Topics: Administration, Oral; Cyclohexanes; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Drug Evaluation; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1974
A clinical study of the metabolic effect of a new oral hypoglycemic agent: glipizide. International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 7, Issue:3 Topics: Adult; Aged; Blood Glucose; Circadian Rhythm; Cyclohexanes; Diabetes Mellitus; Female; Glycosuria; Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds; Tolbutamide	1974
Pharmacological and clinical evaluation of the activity and tolerance of a new oral antidiabetic compound, glydiazinamide or K 4024. Israel journal of medical sciences, 1972, Volume: 8, Issue:6 Topics: Administration, Oral; Adult; Age Factors; Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1972
[Glydiazinamide-induced changes in the oral glucose tolerance of 15 adult diabetics]. Minerva medica, 1972, Oct-03, Volume: 63, Issue:69 Topics: Adult; Aged; Analysis of Variance; Blood Glucose; Chemical Phenomena; Chemistry; Cyclohexanes; Diabetes Mellitus; Drug Tolerance; Evaluation Studies as Topic; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Intestinal Absorption; Male; Middle Aged; Pyrazines; Sulfonylurea Compounds	1972
Possible predisposition of diabetic patients to hyperkalemia following administration of potassium-retaining diuretic, amiloride (MK 870). Metabolism: clinical and experimental, 1970, Volume: 19, Issue:1 Topics: Adult; Aged; Bicarbonates; Blood Pressure; Body Weight; Chemical Phenomena; Chemistry; Chlorides; Creatinine; Diabetes Mellitus; Diuretics; Electrocardiography; Female; Humans; Hyperkalemia; Male; Middle Aged; Potassium; Pyrazines; Sodium; Spironolactone; Triamterene; Water-Electrolyte Balance	1970
[Clinical experience concerning the action of a new oral antidiabetic drug: glidiazinamide]. Minerva medica, 1971, Jul-21, Volume: 62, Issue:57 Topics: Adult; Aged; Cholesterol; Cyclohexanes; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Male; Middle Aged; Pyrazines; Sulfones; Urea	1971