pyrazines has been researched along with Cystic Fibrosis in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, X | 1 |
| Hull-Ryde, EA; Kato, T; Martino, MEB; Minges, JT; Norris-Drouin, JL; Ribeiro, CMP | 1 |
| Anzaldi, M; Galietta, LJ; Mazzei, M; Mazzei, MT; Nieddu, E; Pedemonte, N; Pesce, E; Pollarolo, B; Schenone, S | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Collingwood, S; Danahay, H | 1 |
| Astakhova, N; Boucher, RC; Geiss, WB; Hirsh, AJ; Johnson, MR; Molino, BF; Sargent, BJ; Smith, RT; Swenson, BD; Usyatinsky, A; Wyle, MJ; Zamurs, A; Zhang, J | 1 |
| Briggman, JV; Jenkins, MQ; Patton, CJ; Spicer, SS | 1 |
| Dearborn, DG; Hopfer, U; Lebowitz, JL; Taylor, A; Will, PC | 1 |
7 other study(ies) available for pyrazines and Cystic Fibrosis
| Article | Year |
|---|---|
Drug efficacy and toxicity prediction: an innovative application of transcriptomic data.
Topics: Aminophenols; Aminopyridines; Animals; Antineoplastic Agents; Benzodioxoles; Cell Death; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Combinations; Drug Development; Epithelial Cells; Gene Expression Profiling; Gene Regulatory Networks; Humans; Leukemia, Myeloid, Acute; Pyrazines; Pyrazoles; Quinolones; Toxicity Tests; Transcriptome | 2020 |
IRE1α Is a Therapeutic Target for Cystic Fibrosis Airway Inflammation.
Topics: Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytokines; Endoribonucleases; Epithelium; Humans; Imidazoles; Inflammation; Lung; Models, Biological; Molecular Targeted Therapy; Naphthalenes; Protein Serine-Threonine Kinases; Pyrazines; RNA, Messenger; Up-Regulation; X-Box Binding Protein 1 | 2021 |
The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel.
Topics: Anisoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Deletion; Humans; Models, Molecular; Molecular Conformation; Piperazines; Purines; Pyrazines; Sildenafil Citrate; Sulfonamides; Thiazoles; Vasodilator Agents | 2014 |
ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.
Topics: Administration, Inhalation; alpha 1-Antitrypsin; Amiloride; Animals; Aprotinin; Body Water; Cystic Fibrosis; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Extravascular Lung Water; Fluid Shifts; Guanidines; Lung; Magnetic Resonance Imaging; Male; Mucociliary Clearance; Protease Inhibitors; Pyrazines; Rats; Rats, Inbred BN; Respiratory Mucosa; Saline Solution, Hypertonic; Sodium Channel Blockers; Time Factors | 2010 |
Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.
Topics: Animals; Bronchi; Bronchitis, Chronic; Combinatorial Chemistry Techniques; Cystic Fibrosis; Dogs; Epithelial Sodium Channels; Guanidines; Models, Molecular; Pyrazines; Respiratory Mucosa; Sodium Channel Blockers; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tissue Culture Techniques | 2006 |
Effect of amiloride on potential difference across rectal mucosa in cystic fibrosis patients.
Topics: Adolescent; Adult; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Infant; Intestinal Mucosa; Ion Channels; Membrane Potentials; Pyrazines; Rectum; Sodium; Water-Electrolyte Balance | 1982 |
Saliva from patients with cystic fibrosis inhibits amiloride-sensitive sodium transport.
Topics: Amiloride; Animals; Colon; Cystic Fibrosis; Electrophysiology; In Vitro Techniques; Intestinal Absorption; Male; Pyrazines; Rats; Saliva; Sodium | 1980 |