Compounds > pyrazines
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pyrazines and Congo Virus Infection

pyrazines has been researched along with Congo Virus Infection in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Bailey-Elkin, BA; Götte, M; Mark, BL; Tchesnokov, EP1
Feldmann, F; Feldmann, H; Furuta, Y; Gowen, BB; Haddock, E; Hanley, PW; Hawman, DW; Komeno, T; Lovaglio, J; Meade-White, K; Nakajima, N; Nardone, G; Scott, D1
Bergeron, É; Chatterjee, P; Flint, M; Nichol, ST; Scholte, FEM; Spiropoulou, CF; Welch, SR1
Feldmann, H; Furuta, Y; Gowen, BB; Haddock, E; Hanley, PW; Hawman, DW; Komeno, T; Meade-White, K; Rosenke, K; Williamson, B1
Bernreuther, C; de Lamballerie, X; Emmerich, P; Günther, S; Krasemann, S; Lehmann, M; Neumann, M; Oestereich, L; Ölschläger, S; Rieger, T; Wurr, S1

Other Studies

5 other study(ies) available for pyrazines and Congo Virus Infection

ArticleYear
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:6

    Topics: Amides; Deubiquitinating Enzymes; DNA-Directed RNA Polymerases; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Humans; Mutation; Protein Structure, Tertiary; Pyrazines; Ribavirin; RNA, Viral; Virus Replication

2020
Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques.
    Antiviral research, 2020, Volume: 181

    Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Drug Administration Schedule; Female; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Macaca fascicularis; Male; Pyrazines; Viral Load; Viremia; Virus Shedding

2020
Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus.
    Antiviral research, 2017, Volume: 147

    Topics: Amides; Antiviral Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Discovery; Drug Synergism; Genes, Reporter; Green Fluorescent Proteins; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; High-Throughput Screening Assays; Humans; Lethal Dose 50; Pyrazines; Ribavirin; Viral Proteins; Virus Replication

2017
Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice.
    Antiviral research, 2018, Volume: 157

    Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Mice; Pyrazines; Ribavirin; RNA, Viral; Survival Analysis; Treatment Outcome; Viral Load

2018
Evaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic fever.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:5

    Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Female; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Indoles; Liver; Male; Mice; Mice, Transgenic; Pyrazines; Receptor, Interferon alpha-beta; Ribavirin; Vero Cells

2014