pyrazines has been researched along with Cirrhoses, Experimental Liver in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Chen, X; Chung, RT; Fuchs, BC; He, L; Holmes, JA; Hong, J; Hu, Q; Jiang, Y; Jin, Q; Li, S; Li, W; Liao, Y; Lidofsky, A; Lin, W; Lin, Z; Liu, Y; Qu, C; Tu, M; Wei, L; Yuan, H; Zheng, D | 1 |
| Aihara, Y; Douhara, A; Fukui, H; Ikenaka, Y; Kaji, K; Kawaratani, H; Kitade, M; Moriya, K; Namisaki, T; Noguchi, R; Shirai, Y; Yanase, K; Yoshii, J; Yoshiji, H | 1 |
| Ahn, CY; Bae, SH; Bae, SK; Jung, YS; Kim, T; Kim, YC; Lee, MG; Shin, WG | 1 |
| Bae, SK; Cho, MK; Kang, KW; Kim, CW; Kim, SG; Kim, YG; Lee, MG | 1 |
| Bae, SK; Kim, SG; Lee, I; Lee, JY; Lee, MG; Lee, SJ; Lee, Y | 1 |
| Li, XS; Liu, LY; Liu, ZQ; Tan, LX | 1 |
| Chang, FC; Chen, KJ; Hong, CY; Huang, YT | 1 |
| Chang, FC; Chen, KJ; Hong, CY; Huang, YT; Lin, JG | 1 |
| Choi, SH; Ha, JR; Kang, KW; Kim, CW; Kim, SG | 1 |
9 other study(ies) available for pyrazines and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Tyrosine kinase SYK is a potential therapeutic target for liver fibrosis.
Topics: Animals; Drug Evaluation, Preclinical; Hep G2 Cells; Hepatic Stellate Cells; Hepatocytes; Humans; Indazoles; Liver Cirrhosis, Experimental; Male; Mice, Inbred C57BL; Pyrazines; Rats; Syk Kinase | 2018 |
Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats.
Topics: Animals; Becaplermin; Cell Proliferation; Collagen; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Hepatic Stellate Cells; Liver Cirrhosis, Experimental; Male; Phosphorylation; Proto-Oncogene Proteins c-sis; Pyrazines; Rats; Rats, Inbred F344; Sitagliptin Phosphate; Swine; Transforming Growth Factor beta1; Triazoles | 2014 |
Pharmacokinetics of oltipraz in diabetic rats with liver cirrhosis.
Topics: Animals; Area Under Curve; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Liver; Liver Cirrhosis, Experimental; Pyrazines; Rats; Schistosomicides; Thiones; Thiophenes | 2009 |
Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Extracellular Matrix; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Models, Biological; Pyrazines; Rats; RNA, Messenger; Survival Analysis; Thiones; Thiophenes; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
Topics: Administration, Oral; Animals; Area Under Curve; Blood Proteins; Dimethylnitrosamine; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Protein Binding; Pyrazines; Rats; Rats, Sprague-Dawley; Schistosomicides; Thiones; Thiophenes; Time Factors; Tissue Distribution | 2004 |
[Effects of combination therapy of rehin and tetramethylpyrazine on experimental hepatic fibrosis induced by tetrachloride].
Topics: Animals; Anthraquinones; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drug Therapy, Combination; Liver Cirrhosis, Experimental; Male; Pyrazines; Rats; Rats, Wistar | 2004 |
Acute hemodynamic effects of tetramethylpyrazine and tetrandrine on cirrhotic rats.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Pyrazines; Rats; Rats, Sprague-Dawley | 1999 |
Haemodynamic effects of chronic tetramethylpyrazine administration on portal hypertensive rats.
Topics: Animals; Female; Hemodynamics; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Portal Pressure; Portal Vein; Pyrazines; Rats; Vasodilator Agents | 1999 |
Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-beta1 and tumor necrosis factor-alpha expression.
Topics: Animals; Base Sequence; Dimethylnitrosamine; DNA Primers; Glyceraldehyde-3-Phosphate Dehydrogenases; Liver Cirrhosis, Experimental; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiones; Thiophenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2002 |