Compounds > pyrazines
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pyrazines and Cell Transformation, Neoplastic

pyrazines has been researched along with Cell Transformation, Neoplastic in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's7 (20.59)18.2507
2000's11 (32.35)29.6817
2010's15 (44.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruens, L; Cammareri, P; Campbell, AD; Faller, WJ; Gay, DM; Hodder, MC; Huels, DJ; McLaughlin, ME; Morrissey, E; Nixon, C; Ridgway, RA; Sansom, OJ; Snippert, HJ; Solar-Abboud, M; van Rheenen, J; Winton, DJ; Zeiger, LB1
Alhalouli, T; Bueso-Ramos, C; Burger, J; Estrov, Z; Ferrajoli, A; Jain, N; Jain, P; Kanagal-Shamanna, R; Kantarjian, HM; Keating, M; Khoury, JD; Luthra, R; Medeiros, LJ; Patel, KP; Routbort, M; Wierda, W1
Andersen, KF; Divilov, V; Koziorowski, J; Lewis, JS; Pillarsetty, N1
Chiappetta, G; Di Maro, G; Jarzab, B; Masullo, M; Monaco, M; Oczko-Wojciechowska, M; Orlandella, FM; Salerno, P; Salvatore, G; Santoro, M; Thomas, G; Unger, K1
Chauhan, P; Hart, KM; Liu, CG; Liu, R; Liu, X; Mao, X; Wang, L; Wei, S; Yang, WH; Yi, B; Zhang, W1
Du, Z; Zhang, M; Zhang, Y1
Ahmed, Y; Chen, H; Hu, L; Li, D; Li, Z; Negi, H; Wu, Z; Zheng, Y; Zhu, Q1
Gershon, TR; Hwang, D; Kabanov, AV; Lang, PY; Nanjangud, GJ; Parker, JS; Shaw, C; Sokolsky-Papkov, M1
Carlucci, G; Carney, B; Reiner, T; Sadique, A; Tang, J; Vansteene, A1
Bhargava, R; Carty, SE; Chiosea, SI; Dabbs, D; Dacic, S; Dhir, R; Diaz, R; Ferris, RL; Gandhi, M; Kelly, LM; Kuan, SF; Lee, AV; Liu, P; Nikiforov, YE; Nikiforova, MN; Panebianco, F; Singhi, AD; Trivedi, S; Wald, AI; Wang, X; Zhong, S1
Arenkiel, BR; Capecchi, MR; Cho, MJ; Guttridge, DC; Hansen, MS; Keller, C; McCleish, AT; Qualman, SJ; Rivera, OJ; Scott, MP; Taniguchi, E1
Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K1
Chen, X; Ding, WX; Gao, W; Kang, JH; Liu, J; Ni, HM; Stolz, DB; Yin, XM1
Grant, S1
Bergsagel, PL; Chesi, M; Chng, WJ; Chung, TH; Fonseca, R; Gonzalez-Paz, N; Huang, GF; Mulligan, G; Ng, SB; Troska-Price, T1
Arai, S; Ichikawa, M; Imai, Y; Kataoka, K; Kumano, K; Kurokawa, M; Nakagawa, M; Nannya, Y; Nishimoto, N; Sato, T; Shimabe, M; Shinohara, A; Watanabe-Okochi, N; Yoshimi, A1
Downward, J; Hancock, DC; Howell, M; Kelly, G; Kuznetsov, H; Marani, M; Molina-Arcas, M; Saunders, B; Steckel, M; Warne, PH; Weigelt, B1
De Becker, A; De Raeve, H; Van Camp, B; Van Riet, I; Vanderkerken, K; Xu, S1
Banerjee, A; Gartel, AL; Halasi, M; Kabirov, K; Landolfi, J; Lyubimov, AV; Wang, M1
Adams, GE; Hall, EJ; Hei, TK; Laderoute, KR; Langmuir, VK; Liu, SX; Mendonca, HL; Naylor, MA; Sutherland, RM1
Bai, H1
Adams, J1
Orlowski, RZ; Voorhees, PM1
Davis, JJ; Dong, F; Fang, B; Guo, W; Liu, J; Sasazuki, T; Shirasawa, S; Teraishi, F; Zhang, L1
Barbone, D; Darnowski, JW; Fennell, DA; Galvani, A; Gasparri, F; Gaudino, G; Mutti, L; Nici, L; Porta, C; Sartore-Bianchi, A1
Cameron, IL; Pool, TB; Smith, NK; Sparks, RL1
Feng, YM; Li, ZQ; Luo, XM; Wei, HJ; Zhang, C1
Li, ZQ1
Hall, EJ; Hei, TK; Liu, SX1
Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE1
Hamano, H; Hino, S; Kawamata, H; Miwa, Y; Nakashiro, K; Omotehara, F; Sato, M; Uchida, D; Yoshida, H1
Furukawa, F; Hirose, M; Ikeda, T; Kasahara, KI; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY1
Brenner, DE; Krishnan, K; Ruffin, MT1
Ali, IU; Herbert, BS; Kopelovich, L; Passons, CM; Shay, JW; Wright, AC; Wright, WE1

Reviews

4 review(s) available for pyrazines and Cell Transformation, Neoplastic

ArticleYear
Biomarker development in MET-targeted therapy.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Carcinogenesis; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clinical Trials as Topic; Gene Amplification; Hepatocyte Growth Factor; Humans; Imidazoles; Molecular Targeted Therapy; Mutation; Neoplasms; Patient Selection; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrazines; Signal Transduction; Triazines

2016
The proteasome: a suitable antineoplastic target.
    Nature reviews. Cancer, 2004, Volume: 4, Issue:5

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Endopeptidases; Humans; Multienzyme Complexes; Nuclear Proteins; Proteasome Endopeptidase Complex; Pyrazines; Signal Transduction

2004
The proteasome and proteasome inhibitors in cancer therapy.
    Annual review of pharmacology and toxicology, 2006, Volume: 46

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Humans; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines

2006
Chemoprevention for colorectal cancer.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:3

    Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Apoptosis; Arachidonic Acids; Bile Acids and Salts; Biomarkers; Calcium; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; DNA Repair; Eflornithine; Enzyme Inhibitors; Estrogens; Free Radical Scavengers; Genetic Predisposition to Disease; Humans; Mice; Ornithine Decarboxylase Inhibitors; Patient Compliance; Patient Selection; Polyamines; Precancerous Conditions; Pyrazines; Rats; Retinoids; Thiones; Thiophenes; Tumor Cells, Cultured; Vitamins

2000

Other Studies

30 other study(ies) available for pyrazines and Cell Transformation, Neoplastic

ArticleYear
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.
    Nature communications, 2018, 03-19, Volume: 9, Issue:1

    Topics: Acyltransferases; Adenoma; Adenomatous Polyposis Coli Protein; Animals; Carcinogenesis; Cell Transformation, Neoplastic; Colorectal Neoplasms; Enzyme Inhibitors; Intestinal Mucosa; Ligands; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pyrazines; Pyridines; Stem Cells; Wnt Signaling Pathway

2018
Targeted multigene deep sequencing of Bruton tyrosine kinase inhibitor-resistant chronic lymphocytic leukemia with disease progression and Richter transformation.
    Cancer, 2019, 02-15, Volume: 125, Issue:4

    Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cohort Studies; Disease Progression; DNA Mutational Analysis; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Longitudinal Studies; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Mutation; Piperidines; Prognosis; Pyrazines; Pyrazoles; Pyrimidines

2019
Antilipolytic drug boosts glucose metabolism in prostate cancer.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Fluorodeoxyglucose F18; Glucose; Humans; Hypolipidemic Agents; Male; Mice; Mice, Nude; Positron-Emission Tomography; Prostatic Neoplasms; Pyrazines; Tissue Distribution

2013
Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells.
    Molecular cancer, 2014, Jun-30, Volume: 13

    Topics: Apoptosis; Boronic Acids; Bortezomib; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Endoplasmic Reticulum Stress; Gene Knockdown Techniques; Humans; Mucoproteins; Neoplasm Invasiveness; Oncogene Proteins; Oxidation-Reduction; Protein Disulfide-Isomerases; Proteins; Pyrazines; Thyroid Cancer, Papillary; Thyroid Neoplasms; Up-Regulation

2014
FOXP3-miR-146-NF-κB Axis and Therapy for Precancerous Lesions in Prostate.
    Cancer research, 2015, Apr-15, Volume: 75, Issue:8

    Topics: Animals; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Cells, Cultured; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; MicroRNAs; Precancerous Conditions; Prostate; Prostatic Neoplasms; Pyrazines; Signal Transduction; Xenograft Model Antitumor Assays

2015
Binding of anterior gradient 2 and estrogen receptor-α: Dual critical roles in enhancing fulvestrant resistance and IGF-1-induced tumorigenesis of breast cancer.
    Cancer letters, 2016, 07-10, Volume: 377, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Imidazoles; Insulin-Like Growth Factor I; MCF-7 Cells; Mucoproteins; Oncogene Proteins; Protein Binding; Proteins; Proteolysis; Pyrazines; RNA Interference; Signal Transduction; Time Factors; Transfection

2016
ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
    Development (Cambridge, England), 2016, 11-01, Volume: 143, Issue:21

    Topics: Animals; Animals, Newborn; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Cerebellum; Chromosomal Instability; Developmental Disabilities; Female; Gene Deletion; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Isoxazoles; Male; Medulloblastoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Nervous System Malformations; Neurogenesis; Neurons; Pyrazines

2016
Evaluation of [
    Nuclear medicine and biology, 2017, Volume: 48

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Fluorine Radioisotopes; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrazines; Radioactive Tracers; Radiochemistry; Sulfones; Tissue Distribution

2017
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 02-28, Volume: 114, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Genetic Loci; Genome-Wide Association Study; Humans; Imidazoles; Insulin-Like Growth Factor II; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Oncogene Proteins, Fusion; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Protein Kinase Inhibitors; Pyrazines; Receptor, IGF Type 1; Receptors, Somatomedin; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2017
Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Disease Models, Animal; Gene Knock-In Techniques; Hedgehog Proteins; Humans; Immunoblotting; Immunoprecipitation; Loss of Heterozygosity; Medulloblastoma; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; PAX7 Transcription Factor; Proteasome Endopeptidase Complex; Protein Isoforms; Protein Processing, Post-Translational; Pyrazines; Receptors, Cell Surface

2009
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
    Oncology reports, 2009, Volume: 21, Issue:6

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors

2009
Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:7

    Topics: Animals; Antimalarials; Apoptosis; Autophagy; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chloroquine; Colonic Neoplasms; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Protease Inhibitors; Proteasome Inhibitors; Pyrazines; Xenograft Model Antitumor Assays

2009
Selectively killing transformed cells through proteasome inhibition.
    Cell cycle (Georgetown, Tex.), 2009, Oct-01, Volume: 8, Issue:19

    Topics: Anthracyclines; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Humans; Neoplasms; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Ubiquitination

2009
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma.
    Leukemia, 2011, Volume: 25, Issue:6

    Topics: Boronic Acids; Bortezomib; Cell Cycle; Cell Transformation, Neoplastic; Gene Expression Profiling; Humans; Monoclonal Gammopathy of Undetermined Significance; Multiple Myeloma; Mutation; Proto-Oncogene Proteins c-myc; Pyrazines; ras Proteins; Survival Rate

2011
AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors.
    Blood, 2011, Dec-15, Volume: 118, Issue:25

    Topics: Acute Disease; Animals; Antineoplastic Agents; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Transformation, Neoplastic; Core Binding Factor Alpha 2 Subunit; Cytoplasm; Female; Gene Expression Regulation, Leukemic; HEK293 Cells; Humans; I-kappa B Kinase; Leukemia, Myeloid; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Mutation; NF-kappa B; Protein Binding; Pyrazines; Signal Transduction; Xenograft Model Antitumor Assays

2011
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.
    Cell research, 2012, Volume: 22, Issue:8

    Topics: Alleles; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Colonic Neoplasms; Deoxycytidine; DNA Topoisomerases, Type I; GATA2 Transcription Factor; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mutation; Nuclear Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyrazines; ras Proteins; RNA Interference; RNA, Small Interfering; Topoisomerase I Inhibitors; Topotecan; Transcriptional Activation

2012
In vitro expanded bone marrow-derived murine (C57Bl/KaLwRij) mesenchymal stem cells can acquire CD34 expression and induce sarcoma formation in vivo.
    Biochemical and biophysical research communications, 2012, Aug-03, Volume: 424, Issue:3

    Topics: Animals; Antigens, CD34; Bone Marrow Cells; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Female; Hydroxamic Acids; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Pyrazines; Receptors, Notch; Sarcoma; Vorinostat; Wnt Proteins

2012
Combination treatment with bortezomib and thiostrepton is effective against tumor formation in mouse models of DEN/PB-induced liver carcinogenesis.
    Cell cycle (Georgetown, Tex.), 2012, Sep-15, Volume: 11, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethylnitrosamine; Disease Models, Animal; Liver; Liver Neoplasms; Mice; Phenobarbital; Pyrazines; Thiostrepton

2012
Fused pyrazine mono-n-oxides as bioreductive drugs. II Cytotoxicity in human cells and oncogenicity in a rodent transformation assay.
    International journal of radiation oncology, biology, physics, 1996, Jan-01, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Mice; Mice, Inbred C3H; Pyrazines; Radiobiology; Structure-Activity Relationship; Tumor Cells, Cultured

1996
[Studies on inhibition of human lung carcinogenesis in early stage by oltipraz and its effects on some gene expression and regulation].
    Sheng li ke xue jin zhan [Progress in physiology], 1998, Volume: 29, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Cell Transformation, Neoplastic; Cells, Cultured; Fetus; Gene Expression Regulation, Neoplastic; Humans; Lung; Proto-Oncogene Proteins c-fos; Pyrazines; Tars; Thiones; Thiophenes

1998
Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells.
    Cancer research, 2006, Jun-15, Volume: 66, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Transformation, Neoplastic; Enzyme Activation; Genes, ras; HCT116 Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Mutation; Phosphorylation; Protease Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Pyrazines; ras Proteins; Signal Transduction

2006
Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-01, Volume: 13, Issue:19

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Enzyme Inhibitors; Humans; Male; Mesothelioma; Mice; Mice, Nude; NF-kappa B; Nitriles; Proteasome Inhibitors; Pyrazines; Sulfones; Tumor Necrosis Factor-alpha

2007
Effects of amiloride on tumor growth and intracellular element content of tumor cells in vivo.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Adenocarcinoma; Amiloride; Animals; Body Weight; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Liver Neoplasms, Experimental; Male; Mice; Pyrazines; Sodium

1983
Inhibition of the transforming ability of cigarette smoking condensate-treated human fetal lung DNA induced by oltipraz.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1994, Volume: 13, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Humans; Lung; Nicotiana; Organ Culture Techniques; Plants, Toxic; Pyrazines; Rats; Smoke; Thiones; Thiophenes; Transformation, Genetic

1994
[Study on initiation of human lung carcinogenesis].
    Sheng li ke xue jin zhan [Progress in physiology], 1993, Volume: 24, Issue:4

    Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Humans; Lung Neoplasms; Pyrazines; Smoking; Thiones; Thiophenes

1993
Oncogenic potential of bifunctional bioreductive drugs.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Animals; Antineoplastic Agents; Aziridines; Cell Survival; Cell Transformation, Neoplastic; Indolequinones; Indoles; Mice; Mice, Inbred C3H; Mitomycin; Oxidation-Reduction; Pyrazines; Structure-Activity Relationship

1996
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:8

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes

1997
Down-regulation of TSC-22 (transforming growth factor beta-stimulated clone 22) markedly enhances the growth of a human salivary gland cancer cell line in vitro and in vivo.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Clone Cells; DNA, Antisense; DNA, Complementary; Gene Expression Regulation, Neoplastic; Humans; Leucine Zippers; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Promoter Regions, Genetic; Pyrazines; Quinolines; Recombinant Fusion Proteins; Repressor Proteins; RNA, Messenger; RNA, Neoplasm; Salivary Gland Neoplasms; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1998
Organ-dependent modifying effects of oltipraz on N-nitrosobis(2-oxopropyl)amine (BOP)-initiation of tumorigenesis in hamsters.
    Cancer letters, 2000, May-29, Volume: 153, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Female; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Organ Size; Pyrazines; Thiones; Thiophenes

2000
Effects of chemopreventive and antitelomerase agents on the spontaneous immortalization of breast epithelial cells.
    Journal of the National Cancer Institute, 2001, Jan-03, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Disease Progression; DNA, Complementary; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Li-Fraumeni Syndrome; Oligodeoxyribonucleotides, Antisense; Point Mutation; Pyrazines; Reverse Transcriptase Inhibitors; Tamoxifen; Telomerase; Thiones; Thiophenes; Transformation, Genetic; Tretinoin

2001