pyrazines has been researched along with Cardiomegaly in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Ji, Y; Li, W; Ma, H; Ma, Y; Shen, J; Shen, Y; Su, SA; Wang, Y; Xiang, M; Xie, Y; Zhang, Y | 1 |
| Ares-Carrasco, S; Caro-Vadillo, A; Egido, J; Iborra, C; Lorenzo, O; Picatoste, B; Ramírez, E; Tuñón, J | 1 |
| Ji, XX; Qian, W; Song, XL; Yu, XL; Zhu, JY | 1 |
| Buckley, CL; Horton, JS; Stokes, AJ | 1 |
| Guo, ZQ; Wang, SR; Zhu, LQ | 1 |
| Hilewitz, H; Rogel, S; Weinstein, M | 1 |
| Do, ML; Donahue, JY; Halterman, TJ; Howe, BB; Kau, ST; Keith, RA; Schwartz, JA | 1 |
| Bowman, Z; Cooper, CM; Stanton, HC | 1 |
8 other study(ies) available for pyrazines and Cardiomegaly
| Article | Year |
|---|---|
Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling.
Topics: Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Calcium Signaling; Calpain; Cardiomegaly; Homeostasis; Ion Channels; Isoproterenol; Mechanotransduction, Cellular; Mice; Mice, Knockout; Myocytes, Cardiac; Pyrazines; Rats; Thiadiazoles | 2021 |
Sitagliptin reduces cardiac apoptosis, hypertrophy and fibrosis primarily by insulin-dependent mechanisms in experimental type-II diabetes. Potential roles of GLP-1 isoforms.
Topics: Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Drug Evaluation, Preclinical; Fibroblasts; Fibronectins; Fibrosis; Glucagon-Like Peptide 1; Glucose Intolerance; Hypoglycemic Agents; Insulin; Male; Metformin; Myocardium; Myocytes, Cardiac; PPAR delta; Protein Isoforms; Pyrazines; Rats; Sitagliptin Phosphate; Triazoles | 2013 |
Effects and mechanism of action of ligustrazine on isoprenaline-induced cardiomyocyte hypertrophy.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Hypertrophy; Isoproterenol; Myocytes, Cardiac; Pyrazines; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in mice.
Topics: Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Heart Failure; Humans; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Natriuretic Peptide, Brain; Pyrazines; Pyridines; TRPV Cation Channels | 2013 |
[Effect of danshensu and ligustrazine on related genes of myocardial hypertrophy induced by angiotensin II].
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Drugs, Chinese Herbal; Female; Lactates; Male; Myocytes, Cardiac; Pyrazines; Rats; Rats, Wistar; RNA, Messenger | 2005 |
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors | 1984 |
ICI 206,970: a novel calcium channel blocker with eukalemic diuretic activity.
Topics: Animals; Aorta; Calcium Channel Blockers; Cardiomegaly; Coronary Circulation; Diuretics; Dogs; Electrocardiography; Hypertension; In Vitro Techniques; Male; Pyrazines; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1993 |
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine | 1970 |