pyrazines has been researched along with Burkitt Lymphoma in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baughn, LB; Linden, MA; Mansoor, A; Stessman, HA; Van Ness, B | 1 |
| Choi, Y; Hur, DY; Kim, D; Kim, YS; Lee, HK; Park, GB | 1 |
| Chiang, AK; Hui, KF; Leung, YY; Middeldorp, JM; Yeung, PL | 1 |
| Delić, J; Gobec, M; Markovič, T; Mlinarič-Raščan, I; Prijatelj, M | 1 |
| Berges, C; Daniel, V; Fuchs, D; Naujokat, C; Opelz, G | 2 |
| He, Y; Hu, XX; Lü, SQ; Wang, JM; Yang, JM; Zhou, H | 1 |
| Ambinder, RF; Chen, J; Chong, JM; Foss, CA; Fox, JJ; Fu, DX; Fukayama, M; Hobbs, RF; Kowalski, J; Pomper, MG; Sgouros, G; Tanhehco, Y | 1 |
| Bradner, JE; Cohen, JI; Kawada, J; Mazitschek, R; Zou, P | 1 |
| Chen, YJ; Huang, RX; Huang, XC; Li, XL; Peng, MY; Xie, ZX; Yang, XG | 1 |
| Baldisserotto, A; Destro, F; Gallerani, E; Gavioli, R; Marastoni, M; Marescotti, D; Sforza, F; Sicurella, M | 1 |
| Ambinder, RF; Chen, J; Hayward, SD; Li, H; Shamay, M; Shirley, CM; Zahnow, CA | 1 |
| Churchill, E; Ma, Y; Mahaffey, CM; Martin, SM; McKnight, H; O'Donnell, RT; Tuscano, JM | 1 |
| Bauer, F; Codreanu, I; Dasanu, CA; Padmanabhan, P; Rampurwala, M | 1 |
| Chavez, M; Cohen, JI; Espey, MG; Levine, M; Shatzer, AN; Tu, H | 1 |
| Ambinder, RF; Chen, J; Chong, JM; Foss, CA; Fox, JJ; Fu, DX; Lemas, V; Pomper, MG; Tanhehco, YC | 1 |
| Cohen, JI; Kawada, J; Pesnicak, L; Zou, P | 1 |
| Bloch, A; Bobek, M; Cole, FE; Sharma, RA | 1 |
18 other study(ies) available for pyrazines and Burkitt Lymphoma
| Article | Year |
|---|---|
Stabilization of activation induced cytidine deaminase by bortezomib does not confer increased drug target mutation frequency.
Topics: Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Cytidine Deaminase; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Inhibitory Concentration 50; Mutation; Mutation Rate; Pyrazines | 2014 |
Silencing of PKCη induces cycle arrest of EBV(+) B lymphoma cells by upregulating expression of p38-MAPK/TAp73/GADD45α and increases susceptibility to chemotherapeutic agents.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Drug Resistance, Neoplasm; Herpesvirus 4, Human; Humans; Membrane Potential, Mitochondrial; NF-kappa B; Niacinamide; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyrazines; RNA Interference; RNA, Small Interfering; Sorafenib; Tumor Protein p73; Tumor Suppressor Proteins; Up-Regulation | 2014 |
Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines.
Topics: Animals; Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Boronic Acids; Bortezomib; Burkitt Lymphoma; Caspase 3; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Epstein-Barr Virus Infections; Gene Expression Regulation, Neoplastic; Herpesvirus 4, Human; Histone Deacetylase Inhibitors; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteasome Inhibitors; Proto-Oncogene Proteins; Pyrazines; Up-Regulation; Viral Proteins; Xenograft Model Antitumor Assays | 2014 |
Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-κB.
Topics: Alprostadil; Antineoplastic Agents; Apoptosis; bcl-X Protein; Boronic Acids; Bortezomib; Burkitt Lymphoma; Caspases; Cell Line, Tumor; Doxorubicin; Humans; Jurkat Cells; Leukemia, B-Cell; Lymphoma, B-Cell; NF-kappa B; Pyrazines; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; U937 Cells | 2014 |
HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Division; Cell Line; Cell Membrane; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; G2 Phase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myeloid Cell Leukemia Sequence 1 Protein; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-bcl-2; Pyrazines; rhoA GTP-Binding Protein; Simvastatin | 2008 |
[Synergistic effects of arsenic trioxide and proteasome inhibitor bortezomib on apoptosis induction in Raji cell line].
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Drug Synergism; Humans; Oxides; Protease Inhibitors; Pyrazines | 2008 |
Bortezomib-induced enzyme-targeted radiation therapy in herpesvirus-associated tumors.
Topics: Animals; Antineoplastic Agents; Arabinofuranosyluracil; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Iodine Radioisotopes; Male; Mice; Mice, SCID; Pyrazines; Radiopharmaceuticals; Sarcoma, Kaposi; Stomach Neoplasms; Thymidine Kinase | 2008 |
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
Topics: Anilides; Apoptosis; B-Lymphocytes; Boronic Acids; Bortezomib; Burkitt Lymphoma; Caspase 3; Cell Line, Tumor; Cell Transformation, Viral; Drug Synergism; Enzyme Inhibitors; Genes, Viral; Herpesvirus 4, Human; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Protease Inhibitors; Pyrazines; Reactive Oxygen Species | 2009 |
[Apoptosis of Burkitt's lymphoma Raji cell line induced by bortezomib].
Topics: Apoptosis; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; NF-kappa B; Pyrazines; Tumor Suppressor Protein p53 | 2009 |
Proteasome inhibitors induce the presentation of an Epstein-Barr virus nuclear antigen 1-derived cytotoxic T lymphocyte epitope in Burkitt's lymphoma cells.
Topics: Antigen Presentation; Blotting, Western; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line; Epitopes, T-Lymphocyte; Epstein-Barr Virus Nuclear Antigens; Fluorescent Antibody Technique; Humans; Leupeptins; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; T-Lymphocytes, Cytotoxic | 2011 |
Bortezomib induction of C/EBPβ mediates Epstein-Barr virus lytic activation in Burkitt lymphoma.
Topics: Activating Transcription Factor 4; Activating Transcription Factor 6; Antineoplastic Agents; Boronic Acids; Bortezomib; Burkitt Lymphoma; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; HEK293 Cells; Herpesvirus 4, Human; Humans; Pyrazines; Regulatory Factor X Transcription Factors; Response Elements; Thapsigargin; Trans-Activators; Transcription Factor CHOP; Transcription Factors; Unfolded Protein Response; Virus Activation; X-Box Binding Protein 1 | 2011 |
The HB22.7 Anti-CD22 monoclonal antibody enhances bortezomib-mediated lymphomacidal activity in a sequence dependent manner.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Drug Synergism; Female; Humans; Lymphoma, Mantle-Cell; Mice; Mice, Inbred BALB C; Mice, Nude; Pyrazines; Reactive Oxygen Species; Sialic Acid Binding Ig-like Lectin 2; Xenograft Model Antitumor Assays | 2011 |
Plasmablastic haemato-lymphoid neoplasm with a complex genetic signature of Burkitt lymphoma responding to bortezomib.
Topics: Aged, 80 and over; Antineoplastic Agents; Boronic Acids; Bortezomib; Burkitt Lymphoma; Fatal Outcome; Genes, myc; Herpesvirus 4, Human; Humans; Immunoglobulin M; Lymphoma, Large B-Cell, Diffuse; Male; Neoplasms, Second Primary; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyrazines; Retroperitoneal Neoplasms; Transcriptome; Translocation, Genetic | 2013 |
Ascorbic acid kills Epstein-Barr virus positive Burkitt lymphoma cells and Epstein-Barr virus transformed B-cells in vitro, but not in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Transformed; Cell Line, Tumor; Cell Survival; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Humans; Mice; Pyrazines; Reactive Oxygen Species; Virus Replication | 2013 |
Virus-associated tumor imaging by induction of viral gene expression.
Topics: Animals; Antineoplastic Agents; Arabinofuranosyluracil; Boronic Acids; Bortezomib; Burkitt Lymphoma; Diagnostic Imaging; Gene Expression; Gene Transfer Techniques; Genes, Viral; Herpesvirus 4, Human; Humans; Immunoblotting; Mice; Neoplasms, Experimental; Oncogenic Viruses; Pyrazines; Radionuclide Imaging; Radiopharmaceuticals; Reverse Transcriptase Polymerase Chain Reaction; Thymidine Kinase | 2007 |
Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Boronic Acids; Bortezomib; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Glycoproteins; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Molecular Chaperones; Neoplasm Proteins; Polyubiquitin; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Pyrazines; Tumor Suppressor Protein p53; Ubiquitination | 2008 |
Bortezomib induces apoptosis of Epstein-Barr virus (EBV)-transformed B cells and prolongs survival of mice inoculated with EBV-transformed B cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; bcl-X Protein; Boronic Acids; Bortezomib; Burkitt Lymphoma; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Transformation, Viral; Herpesvirus 4, Human; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, SCID; Multiple Myeloma; NF-kappa B p50 Subunit; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Signal Transduction; Transcription Factor RelA; Ubiquitin-Protein Ligases; Viral Matrix Proteins; Virus Latency; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays | 2007 |
Synthesis and biological activity of some imidazo(4,5-b)pyrazines and their ribonucleosides as purine analogs.
Topics: Animals; Burkitt Lymphoma; Cells; Cells, Cultured; Crystallography; Escherichia coli; Imidazoles; Inosine; Leukemia L1210; Mammary Neoplasms, Experimental; Methods; Mice; Oxides; Purines; Pyrazines; Ribonucleosides; Xanthine Oxidase | 1973 |