Page last updated: 2024-08-21

pyrazines and Brain Injuries

pyrazines has been researched along with Brain Injuries in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, M; Liu, S; Ma, X; Shao, Z; Shi, H; Wang, X; Wu, P1
Du, S; He, G; Sun, Z; Wu, Y; Zhang, X; Zhao, Y; Zhou, L; Zhou, P; Zhuo, LH1
Brandstetter, M; Engelhard, K; Förster, CY; Neuhaus, W; Schaible, EV; Scheffer, D; Thal, SC; Wunder, C1
Chen, H; Gao, C; Liu, W; Liu, X; Shi, H; Zhao, S; Zhao, Z1
Ju, Y; Liu, WK; Ma, L; Zhang, YK1
Chen, J; Chopp, M; Jiang, H; Mahmood, A; Ning, R; Qu, C; Xiong, Y; Zhang, L1
Kawai, N; Kawanishi, M; Nagao, S1
Auguet, M; Chabrier, PE; Demerlé-Pallardy, C1
Auguet, M; Auvin, S; Bigg, D; Chabrier, PE; Cornet, S; Demerlé-Pallardy, C; Gillard-Roubert, V; Guilmard-Favre, C; Marin, JG; Moncada, S; Pignol, B; Roussillot-Charnet, C; Schulz, J; Spinnewyn, B; Viossat, I1
Birraux, G; Bohme, GA; Boireau, A; Damour, D; Debono, MW; Genevois-Borella, A; Jimonet, P; Mignani, S; Pratt, J; Stutzmann, JM; Vuilhorgne, M; Wahl, F1

Reviews

1 review(s) available for pyrazines and Brain Injuries

ArticleYear
Nitric oxide synthases: targets for therapeutic strategies in neurological diseases.
    Cellular and molecular life sciences : CMLS, 1999, Volume: 55, Issue:8-9

    Topics: Alzheimer Disease; Amidines; Amyotrophic Lateral Sclerosis; Animals; Benzylamines; Brain Injuries; Brain Ischemia; Enzyme Induction; Humans; Huntington Disease; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nervous System Diseases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Specificity; Polymethacrylic Acids; Pyrazines; Thiophenes

1999

Other Studies

9 other study(ies) available for pyrazines and Brain Injuries

ArticleYear
Tetramethylpyrazine Protects Against Early Brain Injury and Inhibits the PERK/Akt Pathway in a Rat Model of Subarachnoid Hemorrhage.
    Neurochemical research, 2018, Volume: 43, Issue:8

    Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; eIF-2 Kinase; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage; Vasodilator Agents

2018
Tetramethylpyrazine‑2'O‑sodium ferulate provides neuroprotection against neuroinflammation and brain injury in MCAO/R rats by suppressing TLR-4/NF-κB signaling pathway.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 176

    Topics: Animals; Brain Edema; Brain Injuries; Chemokine CCL2; Cytokines; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammation; Intercellular Adhesion Molecule-1; Male; Neuroprotective Agents; Nitric Oxide Synthase Type II; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA

2019
Inhibition of proteasomal glucocorticoid receptor degradation restores dexamethasone-mediated stabilization of the blood-brain barrier after traumatic brain injury.
    Critical care medicine, 2013, Volume: 41, Issue:5

    Topics: Animals; Blood Gas Analysis; Blood-Brain Barrier; Blotting, Western; Boronic Acids; Bortezomib; Brain Edema; Brain Injuries; Dexamethasone; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Multivariate Analysis; Proteasome Endopeptidase Complex; Pyrazines; Random Allocation; Real-Time Polymerase Chain Reaction; Receptors, Glucocorticoid; Reference Values; RNA, Messenger; Sensitivity and Specificity; Statistics, Nonparametric

2013
Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following subarachnoid hemorrhage in rats.
    Autonomic neuroscience : basic & clinical, 2008, Aug-18, Volume: 141, Issue:1-2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Blotting, Western; Brain Edema; Brain Injuries; Caspase 3; Cerebral Cortex; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intravenous; Male; Motor Activity; Neuroprotective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Time Factors; Tumor Suppressor Protein p53; Vasodilator Agents; Vasospasm, Intracranial

2008
[Impacts of tetramethylpyrazine on BDNF, bFGF expression and neuron-protection in severe brain injury tissue of rat].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008, Volume: 39, Issue:2

    Topics: Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; Female; Fibroblast Growth Factor 2; Immunohistochemistry; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2008
The treatment of traumatic brain injury with velcade.
    Journal of neurotrauma, 2010, Volume: 27, Issue:9

    Topics: Animals; Boronic Acids; Bortezomib; Brain Injuries; Disease Models, Animal; Male; Pyrazines; Rats; Rats, Wistar; Spatial Behavior; Treatment Outcome

2010
Treatment of cold injury-induced brain edema with a nonspecific matrix metalloproteinase inhibitor MMI270 in rats.
    Acta neurochirurgica. Supplement, 2003, Volume: 86

    Topics: Animals; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Cold Temperature; Enzyme Inhibitors; Hydroxamic Acids; Male; Matrix Metalloproteinase Inhibitors; Parietal Lobe; Pyrazines; Rats; Rats, Sprague-Dawley; Staining and Labeling; Sulfonamides

2003
BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: a promising neuroprotective strategy.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Sep-14, Volume: 96, Issue:19

    Topics: Animals; Aorta; Brain Injuries; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gerbillinae; Inhibitory Concentration 50; Kinetics; Lipid Peroxidation; Male; Mice; Myocardial Ischemia; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Organ Culture Techniques; Pyrazines; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors

1999
9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:5

    Topics: Animals; Anticonvulsants; Brain Injuries; Brain Ischemia; Disease Models, Animal; Gerbillinae; Imidazoles; Male; Neuroprotective Agents; Oocytes; Protein Binding; Pyrazines; Radioligand Assay; Rats; Receptors, AMPA; Reperfusion Injury; Seizures; Spinal Cord Compression; Synapses; Xenopus

2002