Page last updated: 2024-08-21

pyrazines and Benign Cerebellar Neoplasms

pyrazines has been researched along with Benign Cerebellar Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, A; Maharaj, A; Roussel, MF; Stewart, CF; Zhong, B1
Chi, G; Li, D; Xu, D; Zhao, C1
Gershon, TR; Hwang, D; Kabanov, AV; Lang, PY; Nanjangud, GJ; Parker, JS; Shaw, C; Sokolsky-Papkov, M1
Arenkiel, BR; Capecchi, MR; Cho, MJ; Guttridge, DC; Hansen, MS; Keller, C; McCleish, AT; Qualman, SJ; Rivera, OJ; Scott, MP; Taniguchi, E1
Duong, TQ; Jung, I; Keller, C; Kilcoyne, A; Lin, AL; Morgan, WW; Nelon, LD; Nowak, BM; Ohshima-Hosoyama, S; Prajapati, SI; Rubin, BP; Samano, AK; Taniguchi, E; Togao, O; Whitney, TG1
Deckard, LA; Logsdon, NJ; Sontheimer, H; Spiller, SE1
Davare, MA; Hosoyama, T; Keller, C; Nelon, LD; Ohshima-Hosoyama, S1
Buettner, R; Chang, S; Hedvat, M; Jove, R; Jove, V; Liu, L; Scuto, A; Tian, Y; Van Meter, T; Wen, W; Yang, F; Yen, Y; Yip, ML1

Other Studies

8 other study(ies) available for pyrazines and Benign Cerebellar Neoplasms

ArticleYear
Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study.
    Journal of pharmaceutical and biomedical analysis, 2018, Jul-15, Volume: 156

    Topics: Animals; Blood-Brain Barrier; Brain; Calibration; Cerebellar Neoplasms; Checkpoint Kinase 1; Child; Chromatography, Liquid; Chromatography, Reverse-Phase; Dialysis Solutions; Female; Humans; Limit of Detection; Liquid-Liquid Extraction; Medulloblastoma; Mice; Mice, Nude; Microdialysis; Protein Kinase Inhibitors; Pyrazines; Pyrazoles; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry; Xenograft Model Antitumor Assays

2018
Ligustrazine Inhibits Growth, Migration and Invasion of Medulloblastoma Daoy Cells by Up-Regulation of miR-211.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:5

    Topics: Antagomirs; Apoptosis Regulatory Proteins; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cerebellar Neoplasms; Humans; Matrix Metalloproteinase 2; Medulloblastoma; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrazines; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Vasodilator Agents

2018
ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
    Development (Cambridge, England), 2016, 11-01, Volume: 143, Issue:21

    Topics: Animals; Animals, Newborn; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Cerebellum; Chromosomal Instability; Developmental Disabilities; Female; Gene Deletion; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Isoxazoles; Male; Medulloblastoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Nervous System Malformations; Neurogenesis; Neurons; Pyrazines

2016
Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Disease Models, Animal; Gene Knock-In Techniques; Hedgehog Proteins; Humans; Immunoblotting; Immunoprecipitation; Loss of Heterozygosity; Medulloblastoma; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; PAX7 Transcription Factor; Proteasome Endopeptidase Complex; Protein Isoforms; Protein Processing, Post-Translational; Pyrazines; Receptors, Cell Surface

2009
Functional evaluation of therapeutic response for a mouse model of medulloblastoma.
    Transgenic research, 2010, Volume: 19, Issue:5

    Topics: Animals; Antineoplastic Agents; Ataxia; Boronic Acids; Bortezomib; Cerebellar Neoplasms; Disease Models, Animal; Disease Progression; Drug Screening Assays, Antitumor; Gait Disorders, Neurologic; Lameness, Animal; Magnetic Resonance Imaging; Medulloblastoma; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; Protease Inhibitors; Psychomotor Performance; Pyrazines; Receptors, Cell Surface

2010
Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo.
    BMC cancer, 2011, Apr-14, Volume: 11

    Topics: Animals; Boronic Acids; Bortezomib; Cell Growth Processes; Cell Line, Tumor; Cerebellar Neoplasms; Curcumin; Ditiocarb; Humans; I-kappa B Proteins; Medulloblastoma; Mice; Mice, Inbred C57BL; Mice, Nude; NF-kappa B; Pyrazines; Pyrrolidines; Signal Transduction; Sulfasalazine; Thiocarbamates; Transgenes; Tumor Burden; Xenograft Model Antitumor Assays

2011
Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cells, Cultured; Cerebellar Neoplasms; Gene Expression Profiling; Immunohistochemistry; Medulloblastoma; Mice; Mice, Mutant Strains; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering

2011
Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.
    Cancer biology & therapy, 2012, Volume: 13, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-Associated Death Protein; Boronic Acids; Bortezomib; Caspase 3; Caspase 9; Cerebellar Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cytochromes c; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Medulloblastoma; NF-kappa B; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Sorafenib; Tumor Cells, Cultured

2012