pyrazines has been researched along with B16 Melanoma in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erdoğan, E; Genç, O; Savran, B; Yerlikaya, A | 1 |
| Kim, SY; Min, S; Yeom, GG | 1 |
| Ashton, G; Brognard, J; Carragher, N; Davies, L; Ejiama, S; Fish, L; Frame, M; Fusi, A; Girotti, MR; Hohloch, J; Johnson, L; Lopes, F; Lorigan, P; Macleod, K; Marais, R; Marusiak, AA; McLeary, R; Menard, D; Niculescu-Duvaz, D; Pedersen, M; Preece, N; Sanchez-Laorden, B; Saturno, G; Springer, C; Suijkerbuijk, BM; Viros, A; Whittaker, S; Zambon, A | 1 |
| Jiang, J; Liu, J; Wang, Y; Wu, X; Xu, J; Xu, S; Yao, H; Ye, W; Zhang, H; Zhu, P | 1 |
| Kasaoka, T; Nakajima, M; Nishiyama, H; Okada, M | 1 |
| Chen, L; Gao, M; Lei, N; Lu, Y; Wang, AY; Wu, JM; Xu, B; Zhang, CB; Zhang, LJ; Zhang, WW; Zheng, SZ | 1 |
| Childs, R; Lundqvist, A; Rao, S; Su, S | 1 |
| Yerlikaya, A | 1 |
| Bonavida, B; Comin-Anduix, B; Dissette, VB; Economou, JS; Garban, HJ; Glaspy, JA; McBride, WH; Owens, SK; Ribas, A; Schumacher, LY; Vo, DD | 1 |
| de la Vega, CM; Fernández, Y; Nikolovska-Coleska, Z; Riblett, M; Soengas, MS; Verhaegen, M; Wang, S; Wolter, KG | 1 |
| Chen, Y; Cheng, T; Di, G; Jin, W; Li, J; Li, W; Shao, Z; Wu, J; Yao, M | 1 |
| Liu, J; Qiang, W; Ye, S | 1 |
| Ishiguro, Y; Kawagishi, H; Kobayashi, K; Mori, H; Sakamoto, H; Sugiyama, K; Tanaka, A; Uramato, M | 1 |
| Dykes, DJ; Griswold, DP; Harrison, SD; Plowman, J; Waud, WR | 1 |
14 other study(ies) available for pyrazines and B16 Melanoma
| Article | Year |
|---|---|
Anticancer agent ukrain and bortezomib combination is synergistic in 4T1 breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine Alkaloids; Boronic Acids; Bortezomib; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Humans; Melanoma, Experimental; Phenanthridines; Pyrazines | 2014 |
2,3,5,6-Tetramethylpyrazine of Ephedra sinica regulates melanogenesis and inflammation in a UVA-induced melanoma/keratinocytes co-culture system.
Topics: Animals; Cell Line; Cell Line, Tumor; Coculture Techniques; Cytokines; Ephedra sinica; Humans; Inflammation; Keratinocytes; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Nitric Oxide; Pyrazines; Ultraviolet Rays | 2014 |
Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyrazines; src-Family Kinases; Xenograft Model Antitumor Assays | 2015 |
Design, synthesis and antitumor activity of triterpenoid pyrazine derivatives from 23-hydroxybetulinic acid.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; G1 Phase; HeLa Cells; Humans; Liver Neoplasms; Melanoma, Experimental; Mice; Molecular Structure; Morpholines; Pyrazines; Structure-Activity Relationship; Triterpenes | 2015 |
Matrix metalloproteinase inhibitor, MMI270 (CGS27023A) inhibited hematogenic metastasis of B16 melanoma cells in both experimental and spontaneous metastasis models.
Topics: Animals; Hydroxamic Acids; Lung Neoplasms; Male; Matrix Metalloproteinase Inhibitors; Melanoma, Experimental; Mice; Neoplasm Metastasis; Protease Inhibitors; Pyrazines; Sulfonamides | 2008 |
Ligustrazine inhibits B16F10 melanoma metastasis and suppresses angiogenesis induced by Vascular Endothelial Growth Factor.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Female; Fibroblasts; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Pathologic; Pyrazines; Rats; Vascular Endothelial Growth Factor A | 2009 |
Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Transformed; Cell Line, Tumor; Cells, Cultured; Clone Cells; Coculture Techniques; Cytotoxicity Tests, Immunologic; Epitopes, T-Lymphocyte; Immunity, Innate; Immunization; Killer Cells, Natural; Melanoma, Experimental; Mice; Mice, SCID; Pyrazines; T-Lymphocytes, Cytotoxic | 2010 |
Expression of heme oxygenase-1 in response to proteasomal inhibition.
Topics: Animals; Base Sequence; Blotting, Western; Boronic Acids; Bortezomib; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Induction; Female; Genes, p53; Heme Oxygenase-1; Humans; Leupeptins; Melanoma, Experimental; Mice; Molecular Sequence Data; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Regulatory Sequences, Nucleic Acid | 2012 |
Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade).
Topics: Animals; Apoptosis; Boronic Acids; Bortezomib; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytotoxicity, Immunologic; Dendritic Cells; Immunization; Immunotherapy; In Vitro Techniques; Killer Cells, Natural; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Protease Inhibitors; Pyrazines; Tumor Necrosis Factor-alpha | 2006 |
Therapeutic window for melanoma treatment provided by selective effects of the proteasome on Bcl-2 proteins.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Caspases; Cell Line, Tumor; Gossypol; Humans; Melanoma, Experimental; Mice; Neoplasm Transplantation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Transplantation, Heterologous | 2007 |
TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade.
Topics: Animals; Apoptosis; Boronic Acids; Bortezomib; DNA-Binding Proteins; Early Growth Response Transcription Factors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Harringtonines; Homoharringtonine; Humans; K562 Cells; Kruppel-Like Transcription Factors; Melanoma, Experimental; Mice; Mitochondria; Pyrazines; Transcription Factors | 2007 |
[Effect of tetramethylpyrazine on lymphocytes proliferation response of murine splenocytes].
Topics: Adjuvants, Immunologic; Animals; Cell Division; Lymphocyte Activation; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Pyrazines; Spleen | 1995 |
A pyradine-derivative from the mushroom Albatrellus confluens.
Topics: Animals; Basidiomycota; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Melanins; Melanoma, Experimental; Mice; Plant Extracts; Pyrazines | 1996 |
Schedule dependence, activity against natural metastases, and cross-resistance of pyrazine diazohydroxide (sodium salt, NSC 361456) in preclinical models in vivo.
Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazines | 1990 |