pyrazines has been researched along with Arrhythmia in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bohne, LJ; Dorey, TW; Jansen, HJ; Jones, DL; Liu, Y; Rose, RA; Tuomi, JM | 1 |
| Addison, D; Awan, F; Azali, L; Bhat, SA; Byrd, JC; Chen, ST; Gambril, J; Grever, M; Kalathoor, S; Kittai, A; Palettas, M; Rogers, KA; Rosen, L; Ruz, P; Wiczer, TE; Woyach, J; Zhao, Q | 1 |
| Lamanna, N; Lipsky, A | 1 |
| Cheng, H; Jiang, F; Wang, S; Wu, K; Xiao, B; Yin, K; Zhang, M; Zhou, Z | 1 |
| Durdagi, S; Kayık, G; Tüzün, NŞ | 1 |
| Biava, G; Chinello, P; Ippolito, G; Nicastri, E; Petrosillo, N; Pittalis, S | 1 |
| Chen, SY; Cheng, PY; Hsiao, G; Hwang, HR; Lee, YM | 1 |
| Curtis, MJ; Rees, SA | 1 |
| Bourge, RC; Cohn, JN; DeMets, DL; Goldstein, SO; Gottlieb, SO; Greenberg, BH; Jaski, BE; Lorell, BH; McGrew, F; White, BG | 1 |
| Feng, J; Tang, S; Wu, G | 1 |
| Endoh, M; Hino, M; Sakato, M; Sugawara, H; Yoshimura, A; Yoshioka, K | 1 |
| Bochner, F; McLaran, CJ; Whiting, GF | 1 |
| Segre, G; Tilser, I | 1 |
| Banach, S; Greco, J; Seller, RH; Seth, R | 1 |
| Greeff, K; Köhler, E | 1 |
| Baughman, KL; Becker, LC; Feldman, AM; Gottlieb, SH; Lee, WK; Strobeck, JE; Weiss, JL | 1 |
| Fukuda, K; Handa, S; Kawamura, Y; Nakamura, Y; Ogawa, S | 2 |
| Hashimoto, K; Mitsuhashi, H | 1 |
| Gilly, R; Herne, N; Le Gall, F; Michaud, J; Roux, M | 1 |
| Chapelle, M; Chiche, P | 1 |
| Classen, HG; Solymoss, B; Varga, S | 1 |
1 review(s) available for pyrazines and Arrhythmia
| Article | Year |
|---|---|
Managing toxicities of Bruton tyrosine kinase inhibitors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Animals; Arrhythmias, Cardiac; Arthralgia; Benzamides; Diarrhea; Hemorrhage; Humans; Hypertension; Infection Control; Infections; Male; Piperidines; Protein Kinase Inhibitors; Pyrazines | 2020 |
2 trial(s) available for pyrazines and Arrhythmia
| Article | Year |
|---|---|
A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators.
Topics: Aged; Agranulocytosis; Angiotensin-Converting Enzyme Inhibitors; Arrhythmias, Cardiac; Cardiotonic Agents; Death, Sudden; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged; Pyrazines; Quality of Life; Quinolines; Survival Analysis | 1998 |
Usefulness of OPC-8212, a quinolinone derivative, for chronic congestive heart failure in patients with ischemic heart disease or idiopathic dilated cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Double-Blind Method; Female; Heart Failure; Humans; Male; Middle Aged; Physical Exertion; Pyrazines; Quality of Life; Quinolines | 1991 |
19 other study(ies) available for pyrazines and Arrhythmia
| Article | Year |
|---|---|
Distinct Effects of Ibrutinib and Acalabrutinib on Mouse Atrial and Sinoatrial Node Electrophysiology and Arrhythmogenesis.
Topics: Action Potentials; Adenine; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Benzamides; Cardiac Electrophysiology; Mice; Myocytes, Cardiac; Piperidines; Pyrazines; Sinoatrial Node | 2021 |
Ventricular arrhythmias and sudden death events following acalabrutinib initiation.
Topics: Aged; Arrhythmias, Cardiac; Benzamides; Death, Sudden; Heart Failure; Humans; Pyrazines | 2022 |
The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Signaling; Cardiomyopathies; Gene Deletion; Heart Failure; Heart Function Tests; Homeostasis; Ion Channels; Mechanotransduction, Cellular; Mice, Knockout; Myocardium; Myocytes, Cardiac; Organ Specificity; Pyrazines; Reactive Oxygen Species; Thiadiazoles; Up-Regulation | 2021 |
Structural investigation of vesnarinone at the pore domains of open and open-inactivated states of hERG1 K
Topics: Arrhythmias, Cardiac; ERG1 Potassium Channel; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Potassium Channel Blockers; Protein Conformation; Pyrazines; Quinolines | 2017 |
QTc interval prolongation during favipiravir therapy in an Ebolavirus-infected patient.
Topics: Adult; Amides; Antiviral Agents; Arrhythmias, Cardiac; Ebolavirus; Electrocardiography; Hemorrhagic Fever, Ebola; Humans; Italy; Levofloxacin; Male; Pyrazines; RNA-Dependent RNA Polymerase; Virus Replication | 2017 |
Tetramethylpyrazine induces heme oxygenase-1 expression and attenuates myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Chemotaxis; Fibrinolytic Agents; Gene Expression; Heme Oxygenase-1; Humans; Ligusticum; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Superoxides | 2006 |
Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Heart; Hemodynamics; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Pyrazines; Pyridines; Rabbits; Rats; Rats, Wistar; Ventricular Fibrillation | 1993 |
The effects of tetramethylpyrazine on the incidence of arrhythmias and the release of PGI2 and TXA2 in the ischemic rat heart.
Topics: Animals; Arrhythmias, Cardiac; Epoprostenol; Heart; Male; Myocardial Ischemia; Pyrazines; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 1999 |
Investigation on SCH00013, a novel cardiotonic agent with Ca++ sensitizing action. 4th communication: influence on experimentally induced ventricular arrhythmia in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Agonists; Cardiotonic Agents; Coronary Vessels; Digitalis Glycosides; Dihydropyridines; Dogs; Epinephrine; Female; Heart Ventricles; Hemodynamics; Male; Pyrazines; Pyridazines; Quinolines; Stereoisomerism; Vasoconstrictor Agents; Ventricular Fibrillation | 1999 |
Severe hyperkalaemia with Moduretic.
Topics: Aged; Amiloride; Arrhythmias, Cardiac; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Middle Aged; Pyrazines | 1979 |
The effect of clonidine, triamterene, and amiloride on pharmacokinetics and cardiotoxicity of ouabain in rabbits.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Clonidine; Electrocardiography; Heart Rate; Kinetics; Male; Myocardium; Ouabain; Pyrazines; Rabbits; Time Factors; Triamterene | 1978 |
Increasing the inotropic effect and toxic dose of digitalis by the administration of antikaliuretic drugs--further evidence for a cardiac effect of diuretic agents.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Heart; Myocardial Contraction; Myocardium; Potassium; Pyrazines; Strophanthidin; Strophanthins; Triamterene | 1975 |
[Animal experiments on the effect of triamterene and amiloride on heart and circulation and the toxicity of digoxin (author's transl)].
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Digoxin; Drug Evaluation, Preclinical; Female; Guinea Pigs; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Ouabain; Pyrazines; Triamterene | 1975 |
[How to select newly-developed oral inotropic agents: an evaluation based on their effects on heart rate and arrhythmias].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Dilated; Cardiotonic Agents; Circadian Rhythm; Digitalis; Drug Evaluation; Electrocardiography, Ambulatory; Ethanolamines; Female; Heart Rate; Humans; Male; Middle Aged; Plants, Medicinal; Plants, Toxic; Propanolamines; Pyrazines; Quinolines; Xamoterol | 1990 |
[Usefulness of OPC-8212, an inotropic agent, in patients with chronic congestive heart failure--a multiple dose evaluation on its effect and arrhythmogenesis].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiotonic Agents; Drug Evaluation; Female; Heart Failure; Humans; Male; Middle Aged; Pyrazines; Quinolines | 1988 |
Effects of OPC-8212, a new positive inotropic agent, on canine ventricular arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Dogs; Epinephrine; Female; Heart Ventricles; Male; Myocardial Contraction; Pyrazines; Quinolines; Stimulation, Chemical; Time Factors | 1986 |
[Clinical study of amiloride hydrochloride, a diuretic with low potassium loss].
Topics: Arrhythmias, Cardiac; Blood Urea Nitrogen; Cardiac Complexes, Premature; Diuretics; Drug Synergism; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrhosis; Potassium; Pyrazines; Sodium | 1970 |
[Potassium depletion in cardiology. Action of amiloride, a potassium sparing diuretic].
Topics: Adult; Aged; Amiloride; Arrhythmias, Cardiac; Coronary Disease; Digitalis Glycosides; Diuretics; Female; Heart Diseases; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Potassium Deficiency; Pyrazines | 1973 |
Electrocardiographic alterations in metabolic cardiac necrosis and the influence of amiloride on these changes.
Topics: Acid-Base Equilibrium; Animals; Arrhythmias, Cardiac; Diuretics; Electrocardiography; Female; Heart; Heart Diseases; Heart Rate; Hydrogen-Ion Concentration; Hypernatremia; Hypocalcemia; Myocardium; Necrosis; Pyrazines; Rats; Water-Electrolyte Balance | 1970 |