Page last updated: 2024-08-21

pyrazines and Agranulocytosis

pyrazines has been researched along with Agranulocytosis in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (87.50)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Azadeh, N; Fonseca, R; Kelemen, K	1
Uetrecht, JP; Whitfield, D; Zahid, N	1
Enokihara, H; Furusawa, S; Hayashida, T; Saito, K; Shishido, H; Waga, K; Yamato, R	1
Chen, G	1
Asanoi, H; Furusawa, S; Ohashi, Y	1
Aizawa, S; Handa, H; Hoshi, H; Imai, T; Iwase, O; Kaido, A; Kuriyama, Y; Nabeshima, R; Nakano, M; Sugimoto, K; Tanaka, K; Toyama, K; Yaguchi, M	1
Conrad, CA; Edwards, CL; Forman, A; Freedman, RS; Grothey, A; Grove, W; Hasenburg, A; Kavanagh, JJ; Kudelka, AP; Meyers, CA; Varma, D; Verschraegen, CF	1
Bourge, RC; Cohn, JN; DeMets, DL; Goldstein, SO; Gottlieb, SO; Greenberg, BH; Jaski, BE; Lorell, BH; McGrew, F; White, BG	1

Reviews

1 review(s) available for pyrazines and Agranulocytosis

Article	Year
Vesnarinone-induced granulocytopenia: incidence in Japan and recommendations for safety. Journal of clinical pharmacology, 1996, Volume: 36, Issue:5 Topics: Adult; Agranulocytosis; Cardiotonic Agents; Humans; Incidence; Japan; Male; Product Surveillance, Postmarketing; Pyrazines; Quinolines	1996

Trials

2 trial(s) available for pyrazines and Agranulocytosis

Article	Year
Phase II study of i.v. CI-980 in patients with advanced platinum refractory epithelial ovarian carcinoma. Anti-cancer drugs, 1998, Volume: 9, Issue:5 Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Carbamates; Carcinoma; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Dyspnea; Female; Humans; Hyponatremia; Infusions, Intravenous; Middle Aged; Organoplatinum Compounds; Ovarian Neoplasms; Phlebitis; Pyrazines; Pyridines; Survival Rate; Treatment Outcome	1998
A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators. The New England journal of medicine, 1998, Dec-17, Volume: 339, Issue:25 Topics: Aged; Agranulocytosis; Angiotensin-Converting Enzyme Inhibitors; Arrhythmias, Cardiac; Cardiotonic Agents; Death, Sudden; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged; Pyrazines; Quality of Life; Quinolines; Survival Analysis	1998

Article

Year

Phase II study of i.v. CI-980 in patients with advanced platinum refractory epithelial ovarian carcinoma.

Anti-cancer drugs, 1998, Volume: 9, Issue:5

Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Carbamates; Carcinoma; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Dyspnea; Female; Humans; Hyponatremia; Infusions, Intravenous; Middle Aged; Organoplatinum Compounds; Ovarian Neoplasms; Phlebitis; Pyrazines; Pyridines; Survival Rate; Treatment Outcome

1998

A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators.

The New England journal of medicine, 1998, Dec-17, Volume: 339, Issue:25

Topics: Aged; Agranulocytosis; Angiotensin-Converting Enzyme Inhibitors; Arrhythmias, Cardiac; Cardiotonic Agents; Death, Sudden; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged; Pyrazines; Quality of Life; Quinolines; Survival Analysis

1998

Other Studies

5 other study(ies) available for pyrazines and Agranulocytosis

Article	Year
Amitriptyline-induced agranulocytosis with bone marrow confirmation. Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5 Topics: Agranulocytosis; Amitriptyline; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Boronic Acids; Bortezomib; Cyclophosphamide; Dexamethasone; Diagnosis, Differential; Febrile Neutropenia; Female; Filgrastim; Fractures, Spontaneous; Granulocyte Colony-Stimulating Factor; Humans; Middle Aged; Multiple Myeloma; Osteolysis; Peripheral Nervous System Diseases; Pyrazines; Recombinant Proteins; Urinary Tract Infections	2014
Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3 Topics: Agranulocytosis; Albumins; Cardiotonic Agents; Chromatography, High Pressure Liquid; Glutathione; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Influenza Vaccines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding; Pyrazines; Quinolines	1994
Vesnarinone induced agranulocytosis. American journal of hematology, 1993, Volume: 44, Issue:3 Topics: Aged; Agranulocytosis; Bone Marrow; Colony-Forming Units Assay; Female; Humans; Pyrazines; Quinolines	1993
[Suppression of granulopoiesis by vesnarinone]. Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 1996, Volume: 63, Issue:1 Topics: Adult; Agranulocytosis; Apoptosis; Cardiotonic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Humans; Male; Middle Aged; Pyrazines; Quinolines	1996
Possible involvement of bone marrow stromal cells in agranulocytosis caused by vesnarinone treatment. Acta haematologica, 1997, Volume: 98, Issue:3 Topics: Agranulocytosis; Antineoplastic Agents; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Line; Colony-Forming Units Assay; Cytokines; Humans; Pyrazines; Quinolines; Stromal Cells	1997