pyrazines has been researched along with Aging in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwashita, H; Nakashima, M; Shiraishi, E; Suzuki, N | 1 |
| Afek, A; Arad, M; Aravot, D; El-Ani, D; Eldar, M; Hochhauser, E; Issac, A; Katz, G; Kurtzwald-Josefson, E; Seidman, CE; Seidman, JG; Shainberg, A | 1 |
| Grune, T; Jung, T | 1 |
| Buller, B; Chopp, M; Jiang, J; Jiang, Y; Liu, X; Morris, D; Zhang, L; Zhang, ZG; Zhao, D | 1 |
| Chen, X; Liu, Y; Qi, C; Qiu, F; Xiao, X; Yang, P; Zhang, J | 1 |
| Couto, GK; Crajoinas, RO; Davel, AP; Girardi, AC; Lessa, LM; Pacheco, BP; Rossoni, LV | 1 |
| Bourdel-Marchasson, I; Dejager, S; Schweizer, A | 1 |
| Chopp, M; Kassis, H; Liu, X; Tang, T; Teng, H; Zhang, L; Zhang, ZG | 1 |
| Bergamini, E; Carresi, C; Cavallini, G; Donati, A; Gori, Z; Parentini, I | 1 |
| Angelucci, R; Briatico-Vangosa, G; Lovisolo, PP; Orsini, G; Ronchi, R | 1 |
| Leffingwell, JC; Schiffman, SS | 1 |
| Fujiwara, T; Hattori, K; Hirata, Y; Kobayashi, Y; Kojima, T | 1 |
| Lanzi, R; Malighetti, ME; Manzoni, MF; Pontiroli, AE | 1 |
| Watanabe, H | 1 |
| Mikkelsen, E; Pedersen, OL | 1 |
| Kimura, H; Nakano, M; Nishida, A; Sugioka, K | 1 |
| Anderson, L; Bueding, E; Lawson, TA; Stohs, SJ | 1 |
| Lawson, T; Stohs, S | 1 |
2 review(s) available for pyrazines and Aging
| Article | Year |
|---|---|
The proteasome and its role in the degradation of oxidized proteins.
Topics: Aging; Animals; Antioxidants; Boronic Acids; Bortezomib; Humans; Models, Biological; Multienzyme Complexes; Oxidation-Reduction; Oxidative Stress; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteins; Pyrazines; Substrate Specificity; Ubiquitin; Ubiquitination | 2008 |
Incretin therapies in the management of elderly patients with type 2 diabetes mellitus.
Topics: Adamantane; Age Factors; Aged; Aging; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Incretins; Linagliptin; Liraglutide; Male; Middle Aged; Nitriles; Peptides; Piperidines; Purines; Pyrazines; Pyrrolidines; Quinazolines; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Uracil; Venoms; Vildagliptin | 2011 |
2 trial(s) available for pyrazines and Aging
| Article | Year |
|---|---|
Restoration of growth hormone (GH) response to GH-releasing hormone in elderly and obese subjects by acute pharmacological reduction of plasma free fatty acids.
Topics: Adult; Aged; Aging; Blood Glucose; Cross-Over Studies; Fatty Acids, Nonesterified; Female; Gonadotropin-Releasing Hormone; Human Growth Hormone; Humans; Hypolipidemic Agents; Insulin; Lipolysis; Male; Obesity; Pyrazines; Single-Blind Method | 1996 |
Individual factors influencing the response to a beta-adrenergic blocking agent given alone and in combination with a diuretic on arterial hypertension.
Topics: Adult; Aging; Amiloride; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Time Factors; Timolol | 1979 |
14 other study(ies) available for pyrazines and Aging
| Article | Year |
|---|---|
TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models.
Topics: Aging; Animals; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Male; Memory Disorders; Memory, Episodic; Phosphodiesterase Inhibitors; Pyrazines; Pyridines; Rats; Rats, Inbred F344; Rats, Long-Evans; Rats, Sprague-Dawley | 2019 |
The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).
Topics: Aging; Animals; Animals, Newborn; Boronic Acids; Bortezomib; Calcium; Calsequestrin; Cells, Cultured; Gene Expression; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myocytes, Cardiac; Pyrazines; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Severity of Illness Index; Tachycardia, Ventricular | 2013 |
Combination treatment with VELCADE and low-dose tissue plasminogen activator provides potent neuroprotection in aged rats after embolic focal ischemia.
Topics: Aging; Animals; Boronic Acids; Bortezomib; Brain Ischemia; Drug Administration Schedule; Drug Therapy, Combination; Intracranial Embolism; Male; Neuroprotective Agents; Protease Inhibitors; Pyrazines; Rats; Rats, Wistar; Tissue Plasminogen Activator | 2010 |
Neuroprotection and enhanced neurogenesis by tetramethylpyrazine in adult rat brain after focal ischemia.
Topics: Adult Stem Cells; Aging; Animals; Body Water; Brain; Brain Infarction; Brain Ischemia; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Neurogenesis; Neurons; Neuroprotective Agents; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Stem Cell Niche | 2010 |
Dipeptidyl peptidase IV inhibition attenuates blood pressure rising in young spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Hypertension; Kidney; Kidney Tubules, Proximal; Male; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sitagliptin Phosphate; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Triazoles | 2011 |
Combination therapy with VELCADE and tissue plasminogen activator is neuroprotective in aged rats after stroke and targets microRNA-146a and the toll-like receptor signaling pathway.
Topics: Aging; Animals; Boronic Acids; Bortezomib; Cells, Cultured; Down-Regulation; Drug Therapy, Combination; Humans; Male; MicroRNAs; Neuroprotective Agents; NF-kappa B; Pyrazines; Rats; Rats, Wistar; Signal Transduction; Stroke; Tissue Plasminogen Activator; Toll-Like Receptors | 2012 |
Anti-aging effects of anti-lipolytic drugs.
Topics: Aging; Animals; Autophagy; Blood Glucose; Caloric Restriction; Chromatography, High Pressure Liquid; Dolichols; Energy Intake; Fatty Acids, Nonesterified; Hypolipidemic Agents; Insulin; Liver; Male; Pyrazines; Rats; Rats, Sprague-Dawley | 2004 |
Pharmacological profile of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) II - Antilipolytic and blood lipid lowering activity.
Topics: Aging; Animals; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Hypolipidemic Agents; Lipids; Lipolysis; Liver; Mice; Nicotinic Acids; Pyrazines; Rats; Triglycerides | 1981 |
Perception of odors of simple pyrazines by young and elderly subjects: a multidimensional analysis.
Topics: Adult; Aged; Aging; Humans; Odorants; Prejudice; Pyrazines; Sensory Receptor Cells; Sensory Thresholds; Smell | 1981 |
Maturational changes in superoxide anion production of rabbit alveolar macrophages.
Topics: Aging; Animals; Cells, Cultured; Endothelins; Imidazoles; Luminescent Measurements; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Pyrazines; Rabbits; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Candidates for cognitive enhancer extracted from medicinal plants: paeoniflorin and tetramethylpyrazine.
Topics: Aging; Animals; Basal Ganglia; Benzoates; Bridged-Ring Compounds; Cognition; Discrimination Learning; Free Radical Scavengers; Glucosides; Male; Maze Learning; Memory, Short-Term; Monoterpenes; Nootropic Agents; Plants, Medicinal; Pyrazines; Rats; Rats, Inbred F344; Rats, Wistar | 1997 |
The ability of granulocytes to generate superoxide anions and hypochlorite during phagocytosis: comparison of neonatal granulocytes with adult granulocytes.
Topics: Adult; Aging; Anions; Fetal Blood; Firefly Luciferin; Granulocytes; Humans; Hypochlorous Acid; Infant, Newborn; Luminescent Measurements; Phagocytosis; Pyrazines; Superoxides | 1990 |
Effects of oltipraz, BHA, ADT and cabbage on glutathione metabolism, DNA damage and lipid peroxidation in old mice.
Topics: Aging; Anethole Trithione; Animals; Anisoles; Brassica; Butylated Hydroxyanisole; Diet; DNA; Female; Freeze Drying; Glutathione; Glutathione Reductase; Lipid Peroxides; Mice; Pyrazines; Thiones; Thiophenes | 1986 |
Changes in endogenous DNA damage in aging mice in response to butylated hydroxyanisole and oltipraz.
Topics: Aging; Animals; Antioxidants; Butylated Hydroxyanisole; DNA, Single-Stranded; Female; Glutathione; Liver; Mice; Mice, Inbred Strains; Pyrazines; Thiones; Thiophenes | 1985 |