Page last updated: 2024-08-21

pyrazines and Acute Liver Injury, Drug-Induced

pyrazines has been researched along with Acute Liver Injury, Drug-Induced in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (25.00)	18.7374
1990's	3 (15.00)	18.2507
2000's	3 (15.00)	29.6817
2010's	3 (15.00)	24.3611
2020's	6 (30.00)	2.80

Authors

Authors	Studies
Fenioux, C; Funck-Brentano, C; Gligorov, J; Gougis, P; Solas, C; Spano, JP; Veyri, M	1
Al-Sanea, MM; Alharbi, KS; El-Mesery, ME; Gomaa, HAM; Hazem, SH; Shaker, ME	1
Igari, H; Ishii, I; Nakada, TA; Sayama, M; Suzuki, T; Yamazaki, S	1
Ji, X; Ma, X; Peng, H; Ruan, Q; Yang, J	1
Hao, S; Ishfaq, M; Li, C; Li, R; Liu, F; Ma, B; Shi, C; Wang, J; Yuan, L; Zhang, R; Zhang, Y	1
Demir, B; Demir, E; Sütcüoğlu, O; Ünsal, O; Yazıcı, O	1
Caballero, D; Caballero-Velázquez, T; Castilla-Llorente, C; Encinas, C; Heras, I; López-Corral, L; Martino, R; Pérez-Simón, JA; Rosiñol, L; Sampol, A; San Miguel, J; Serrano, D	1
Hibi, T; Kaneko, F; Motoori, T; Oda, M; Ohbu, M; Shimizu, Y; Tahara, K; Takeuchi, H; Toyoda-Akui, M; Yokomori, H	1
Beckers, EA; Cornelis, T; Driessen, AL; Koek, GH; van der Sande, FM	1
Farombi, EO; Surh, YJ	1
Bayne, R; Bréchot, C; Christa, L; Cortes, A; Hunt, SP; Kebede, M; Lieu, HT; Nguyen-Khoa, T; Simon, MT; Smith, AJ; Tebar, L	1
Lachowicz, D; Siekierzyńska, A; Styszewska, H	1
Fesce, E; Iamoni, G; Ideo, G; Lanzani, F; Mondazzi, L; Zavaglia, C	1
Baumann, H; Jacob, CO; Kambayashi, T; Lazarus, DD; Strassmann, G; Yato-Kioka, M	1
Ha, TG; Kim, ND	1
Lin, CC; Lin, SC; Liu, CF; Ng, LT	1
Charmot, G; Coulaud, JP; Marche, C; Penalba, C; Saimot, AG	1
Ford, EJ	1
Richard, JL	1
Eule, H	1

Reviews

3 review(s) available for pyrazines and Acute Liver Injury, Drug-Induced

Article	Year
Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. Journal of biochemistry and molecular biology, 2006, Sep-30, Volume: 39, Issue:5 Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Garlic; Heme Oxygenase-1; Humans; Liver; Liver Diseases; Metals, Heavy; Pyrazines; Signal Transduction; Thiones; Thiophenes	2006
Mycotoxin photosensitivity. Journal of the American Veterinary Medical Association, 1973, Dec-01, Volume: 163, Issue:11 Topics: Animal Feed; Animals; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Cholestasis; Eczema; Indoles; Liver Diseases; Medicago sativa; Mitosporic Fungi; Mycotoxins; Photosensitivity Disorders; Pyrazines; Pyrroles; Sheep; Sheep Diseases; United States	1973
[Current status of chemotherapy of pulmonary tuberculosis and its further prospectives]. Zeitschrift fur Erkrankungen der Atmungsorgane mit Folia bronchologica, 1971, Volume: 134, Issue:2 Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Drug Resistance, Microbial; Drug Synergism; Drug Tolerance; Hemorrhagic Disorders; Humans; Isoniazid; Kanamycin; Phenylthiourea; Purpura, Thrombocytopenic; Pyrazines; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary	1971

Trials

1 trial(s) available for pyrazines and Acute Liver Injury, Drug-Induced

Article	Year
Phase II clinical trial for the evaluation of bortezomib within the reduced intensity conditioning regimen (RIC) and post-allogeneic transplantation for high-risk myeloma patients. British journal of haematology, 2013, Volume: 162, Issue:4 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cyclosporine; Drug Synergism; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Immunosuppressive Agents; Maintenance Chemotherapy; Male; Melphalan; Middle Aged; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Peripheral Nervous System Diseases; Protease Inhibitors; Pyrazines; Remission Induction; Reoperation; Salvage Therapy; T-Lymphocyte Subsets; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Vidarabine	2013

Article

Year

Phase II clinical trial for the evaluation of bortezomib within the reduced intensity conditioning regimen (RIC) and post-allogeneic transplantation for high-risk myeloma patients.

British journal of haematology, 2013, Volume: 162, Issue:4

Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cyclosporine; Drug Synergism; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Immunosuppressive Agents; Maintenance Chemotherapy; Male; Melphalan; Middle Aged; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Peripheral Nervous System Diseases; Protease Inhibitors; Pyrazines; Remission Induction; Reoperation; Salvage Therapy; T-Lymphocyte Subsets; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Vidarabine

2013

Other Studies

16 other study(ies) available for pyrazines and Acute Liver Injury, Drug-Induced

Article	Year
Anticancer drugs and COVID-19 antiviral treatments in patients with cancer: What can we safely use? European journal of cancer (Oxford, England : 1990), 2020, Volume: 136 Topics: Amides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Immunological; Antiviral Agents; Betacoronavirus; Chemical and Drug Induced Liver Injury; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Histone Deacetylase Inhibitors; Humans; Hydroxychloroquine; Immunosuppression Therapy; Kidney Diseases; Long QT Syndrome; Lopinavir; Neoplasms; Pandemics; Pneumonia, Viral; Poly(ADP-ribose) Polymerase Inhibitors; Proteasome Inhibitors; Protein Kinase Inhibitors; Pyrazines; Ritonavir; SARS-CoV-2	2020
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 131 Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Apoptosis; Benzamides; Chemical and Drug Induced Liver Injury; Cytokines; Fusion Regulatory Protein-1; Galactosamine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Pyrazines	2020
Suspected cholestatic liver injury induced by favipiravir in a patient with COVID-19. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2021, Volume: 27, Issue:2 Topics: Aged; Amides; Antiviral Agents; Chemical and Drug Induced Liver Injury; Cholestasis; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Extracorporeal Membrane Oxygenation; Humans; Lopinavir; Male; Pyrazines; Ritonavir; SARS-CoV-2	2021
Ligustrazine alleviates cyclophosphamide-induced hepatotoxicity via the inhibition of Txnip/Trx/NF-κB pathway. Life sciences, 2021, Jun-01, Volume: 274 Topics: Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Gene Expression Regulation; Inflammasomes; Male; Mice; Mice, Inbred ICR; Mutagens; NF-kappa B; Pyrazines; Thioredoxins; Vasodilator Agents	2021
Drug-induced liver injury: Oltipraz and C2-ceramide intervene HNF-1α/GSTA1 expression via JNK signaling pathway. Journal of applied toxicology : JAT, 2021, Volume: 41, Issue:12 Topics: Chemical and Drug Induced Liver Injury; Glutathione Transferase; Hep G2 Cells; Hepatocyte Nuclear Factor 1-alpha; Humans; MAP Kinase Signaling System; Pyrazines; Sphingosine; Thiones; Thiophenes	2021
A possible interaction between favipiravir and methotrexate: Drug-induced hepatotoxicity in a patient with osteosarcoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:2 Topics: Amides; Antiviral Agents; Bone Neoplasms; Chemical and Drug Induced Liver Injury; COVID-19; Humans; Methotrexate; Osteosarcoma; Pharmaceutical Preparations; Pyrazines; RNA, Viral; SARS-CoV-2	2022
A case of drug-induced hepatic injury associated with sitagliptin. Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:9 Topics: Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Jaundice; Liver; Male; Microscopy, Electron, Transmission; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles	2011
Bortezomib-associated fatal liver failure in a haemodialysis patient with multiple myeloma. Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:5 Topics: Aged; Antineoplastic Agents; Boronic Acids; Bortezomib; Chemical and Drug Induced Liver Injury; Cholestasis; Fatal Outcome; Humans; Liver Failure; Male; Multiple Myeloma; Pyrazines; Renal Dialysis	2012
Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6 Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Chemical and Drug Induced Liver Injury; DNA; Extracellular Signal-Regulated MAP Kinases; fas Receptor; Hepatectomy; Humans; Hydrazines; Interleukin-6; Lectins, C-Type; Liver Regeneration; Mice; Mice, Transgenic; Oncogene Protein v-akt; Pancreatitis-Associated Proteins; Proteins; Pyrazines; Quinolines; Signal Transduction; Tumor Necrosis Factor-alpha	2006
[Value of liver function tests in early detection of hepatotoxicity of antitubercular drugs]. Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1967, Volume: 35, Issue:12 Topics: Alkaline Phosphatase; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Function Tests; Morpholines; Pyrazines; Sulfobromophthalein; Transaminases	1967
Severe acute hepatitis associated with morphazinamide therapy. Journal of hepatology, 1996, Volume: 25, Issue:6 Topics: Acute Disease; Adult; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Female; Humans; Jaundice; Liver Function Tests; Pyrazines	1996
Vesnarinone inhibits immune-mediated but not Fas (CD95) agonist-mediated hepatic injury. International journal of immunopharmacology, 1997, Volume: 19, Issue:1 Topics: Acute-Phase Reaction; Animals; Antibodies, Monoclonal; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Concanavalin A; fas Receptor; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyrazines; Quinolines; Rats; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1997
2-(allylthio)pyrazine inhibition of aflatoxin B1-induced hepatotoxicity in rats: inhibition of cytochrome P450 2B- and 3A2-mediated bioactivation. Research communications in molecular pathology and pharmacology, 1998, Volume: 102, Issue:1 Topics: Aflatoxin B1; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; DNA Adducts; Enzyme Inhibitors; Lipid Peroxidation; Liver; Liver Function Tests; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Transaminases	1998
Hepatoprotective and therapeutic effects of tetramethylpyrazine on acute econazole-induced liver injury. Planta medica, 2002, Volume: 68, Issue:6 Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome c Group; Dose-Response Relationship, Drug; Econazole; Ferrous Compounds; Free Radical Scavengers; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Pyrazines; Rats; Rats, Wistar; Silymarin; Superoxides; Vitamin E	2002
[Eosinophilic granulomatous hepatitis. Apropos of 3 cases]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1987, Volume: 80, Issue:1 Topics: Adult; Chemical and Drug Induced Liver Injury; Eosinophilic Granuloma; Humans; Male; Pyrazines; Schistosomiasis haematobia; Schistosomicides; Thiones; Thiophenes	1987
Activity of gamma-glutamyl transpeptidase and other enzymes in the serum of sheep with liver or kidney damage. Journal of comparative pathology, 1974, Volume: 84, Issue:2 Topics: Alcohol Oxidoreductases; Animals; Arginase; Aspartate Aminotransferases; Bilirubin; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Indoles; Intestine, Small; Kidney; Kidney Diseases; Ligation; Liver; Liver Diseases; Male; Mercury Poisoning; Muscles; Mycotoxins; Myocardium; Pancreas; Pyrazines; Pyrroles; Sheep; Sheep Diseases; Urea	1974