Page last updated: 2024-10-20

pyrazinamide and Tuberculosis, Splenic

pyrazinamide has been researched along with Tuberculosis, Splenic in 6 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Tuberculosis, Splenic: Infection of the spleen with species of MYCOBACTERIUM.

Research Excerpts

ExcerptRelevanceReference
"0, 12 experimental groups, each containing 10 mice, were treated for 8 weeks with pyrazinamide (PZA) given in mean daily dosages of 100, 200 or 400 mg/kg/day, with the interval between the doses within each dosage group being 1, 2, 4 or 8 days."1.28Efficacy of intermittent pyrazinamide in experimental murine tuberculosis. ( Dickinson, JM; Mitchison, DA, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hasan, R1
Kumar, S1
Mathew, M1
Kadavigere, R1
Ibrahim, M1
Truffot-Pernot, C1
Andries, K1
Jarlier, V1
Veziris, N1
Safioleas, MC1
Stamatakos, MC1
Safioleas, CM1
Diab, AI1
Agapitos, EB1
Dickinson, JM1
Mitchison, DA1
McCune, RM2
Feldmann, FM2
Lambert, HP1
McDermott, W2

Other Studies

6 other studies available for pyrazinamide and Tuberculosis, Splenic

ArticleYear
Isolated hepatosplenic tuberculosis: a rare presentation.
    BMJ case reports, 2015, Jul-07, Volume: 2015

    Topics: Abdominal Pain; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazi

2015
Sterilizing activity of R207910 (TMC207)-containing regimens in the murine model of tuberculosis.
    American journal of respiratory and critical care medicine, 2009, Sep-15, Volume: 180, Issue:6

    Topics: Animals; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination;

2009
Co-existence of spontaneous splenic rupture and tuberculosis of the spleen.
    Saudi medical journal, 2006, Volume: 27, Issue:10

    Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Lactones; Male; Pyrazinam

2006
Efficacy of intermittent pyrazinamide in experimental murine tuberculosis.
    Tubercle, 1991, Volume: 72, Issue:2

    Topics: Animals; Colony Count, Microbial; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid

1991
Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues.
    The Journal of experimental medicine, 1966, Mar-01, Volume: 123, Issue:3

    Topics: Animals; Cortisone; Cross Infection; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tube

1966
Microbial persistence. II. Characteristics of the sterile state of tubercle bacilli.
    The Journal of experimental medicine, 1966, Mar-01, Volume: 123, Issue:3

    Topics: Animals; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Tube

1966