pyrazinamide has been researched along with Stevens-Johnson Syndrome in 2 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porter, M | 1 |
| Choshi, P | 1 |
| Pedretti, S | 1 |
| Chimbetete, T | 1 |
| Smith, R | 1 |
| Meintjes, G | 1 |
| Phillips, E | 1 |
| Lehloenya, R | 1 |
| Peter, J | 1 |
| Kura, MM | 1 |
| Hira, SK | 1 |
1 trial available for pyrazinamide and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Reintroducing antituberculosis therapy after Stevens-Johnson syndrome in human immunodeficiency virus-infected patients with tuberculosis: role of desensitization.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antitubercular Age | 2001 |
1 other study available for pyrazinamide and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting.
Topics: Antitubercular Agents; Ethambutol; HIV Infections; Humans; Interferon-gamma; Isoniazid; Pyrazinamide | 2022 |