Page last updated: 2024-10-20

pyrazinamide and Silicosis

pyrazinamide has been researched along with Silicosis in 3 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Silicosis: A form of pneumoconiosis resulting from inhalation of dust containing crystalline form of SILICON DIOXIDE, usually in the form of quartz. Amorphous silica is relatively nontoxic.

Research Excerpts

ExcerptRelevanceReference
"A higher incidence of hepatotoxicity was associated with rifampin plus pyrazinamide than isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong."9.10Initial experience on rifampin and pyrazinamide vs isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong. ( Chan, CK; Chang, KC; Law, WS; Leung, CC; Tam, CM; Wong, MY; Yew, WW, 2003)
"A higher incidence of hepatotoxicity was associated with rifampin plus pyrazinamide than isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong."5.10Initial experience on rifampin and pyrazinamide vs isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong. ( Chan, CK; Chang, KC; Law, WS; Leung, CC; Tam, CM; Wong, MY; Yew, WW, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barboza, CE1
Winter, DH1
Seiscento, M1
Santos, Ude P1
Terra Filho, M1
Leung, CC1
Law, WS1
Chang, KC1
Tam, CM1
Yew, WW1
Chan, CK1
Wong, MY1
Hoeppner, VH1

Reviews

1 review available for pyrazinamide and Silicosis

ArticleYear
Tuberculosis and silicosis: epidemiology, diagnosis and chemoprophylaxis.
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2008, Volume: 34, Issue:11

    Topics: Antibiotics, Antitubercular; Brazil; Humans; Isoniazid; Occupational Exposure; Pyrazinamide; Rifampi

2008

Trials

1 trial available for pyrazinamide and Silicosis

ArticleYear
Initial experience on rifampin and pyrazinamide vs isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong.
    Chest, 2003, Volume: 124, Issue:6

    Topics: Aged; Antitubercular Agents; Drug Administration Schedule; Female; Hong Kong; Humans; Isoniazid; Mal

2003

Other Studies

1 other study available for pyrazinamide and Silicosis

ArticleYear
Short-course chemoprophylaxis evaluated in gold miners with chronic silicosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1997, Volume: 1, Issue:1

    Topics: Antitubercular Agents; Gold; Humans; Isoniazid; Mining; Patient Compliance; Pyrazinamide; Rifampin;

1997