pyrazinamide has been researched along with Pregnancy in 27 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of tuberculosis: A 6-month regimen consisting of isoniazid, rifampin, and pyrazinamide given for 2 months followed by isoniazid and rifampin for 4 months is effective treatment in patients with fully susceptible organisms who comply with the treatment regimen." | 3.67 | American Thoracic Society. Medical Section of the American Lung Association: Treatment of tuberculosis and tuberculosis infection in adults and children. ( , 1986) |
| "When active tuberculosis is identified, combination therapy with isoniazid, rifampin, pyrazinamide, and ethambutol should be promptly initiated for a two-month "intensive phase," and in most cases, followed by isoniazid and a rifamycin product for a four- to seven-month "continuation phase." | 1.35 | Update on the treatment of tuberculosis. ( Inge, LD; Wilson, JW, 2008) |
| "MDR-TB can be successfully treated during pregnancy by using a regimen including effective second-line anti-tuberculosis drugs." | 1.33 | [Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy]. ( Ano, H; Danno, K; Han, Y; Kawahara, K; Matsumoto, T; Nagai, T; Takashima, T; Tamura, Y; Tsuyuguchi, I; Yoshida, H, 2006) |
| "Three patients presenting with tuberculous lymphadenitis during pregnancy are described." | 1.28 | Reactivation of tuberculous lymphadenitis during pregnancy. ( Khoo, SH; Warner, TT; Wilkins, EG, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 9 (33.33) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, AJ | 1 |
| Mathad, JS | 1 |
| Dooley, KE | 1 |
| Eke, AC | 1 |
| Rao, A | 1 |
| Nayak, G | 1 |
| Kumari, S | 1 |
| Kalthur, SG | 1 |
| Mutalik, SP | 1 |
| Mutalik, S | 1 |
| Adiga, SK | 1 |
| Kalthur, G | 1 |
| Inge, LD | 1 |
| Wilson, JW | 1 |
| Kulshrestha, V | 1 |
| Kriplani, A | 1 |
| Agarwal, N | 1 |
| Singh, UB | 1 |
| Rana, T | 1 |
| Kuwabara, K | 1 |
| Garg, K | 1 |
| Mohapatra, PR | 1 |
| HYMAN, C | 1 |
| WILSON, LA | 1 |
| Choudhary, J | 1 |
| Mubarik, M | 1 |
| Parvez, A | 1 |
| Naikoo, MA | 1 |
| Nakanishi, N | 1 |
| Moritaka, T | 1 |
| Ueda, N | 1 |
| Schram, AJ | 1 |
| Holm, JP | 1 |
| van Altena, R | 1 |
| Dam, P | 1 |
| Shirazee, HH | 1 |
| Goswami, SK | 1 |
| Ghosh, S | 1 |
| Ganesh, A | 1 |
| Chaudhury, K | 1 |
| Chakravarty, B | 1 |
| Takashima, T | 1 |
| Danno, K | 1 |
| Tamura, Y | 1 |
| Nagai, T | 1 |
| Matsumoto, T | 1 |
| Han, Y | 1 |
| Ano, H | 1 |
| Yoshida, H | 1 |
| Kawahara, K | 1 |
| Tsuyuguchi, I | 1 |
| Singh, V | 1 |
| Choudhury, P | 1 |
| Puri, RK | 1 |
| Gach, O | 1 |
| Corhay, JL | 1 |
| Lousberg, L | 1 |
| Bartsch, P | 1 |
| James, JS | 1 |
| Nanda, S | 1 |
| Agarwal, U | 1 |
| Sangwan, K | 1 |
| Boman, G | 1 |
| Dahlström, G | 1 |
| Hanngren, A | 1 |
| Stavenow, S | 1 |
| Wiman, LG | 1 |
| Schmidt, M | 1 |
| Warner, TT | 1 |
| Khoo, SH | 1 |
| Wilkins, EG | 1 |
| Rieder, HL | 1 |
| Rieselbach, RE | 1 |
| Steele, TH | 1 |
| Evans, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Short Course Rifapentine and Isoniazid for the Preventive Treatment for Latent Genital Tuberculosis in Women With Recurrent Implantation Failure: A Prospective Interventional Cohort Study[NCT04528277] | Phase 3 | 1,050 participants (Anticipated) | Interventional | 2020-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyrazinamide and Pregnancy
| Article | Year |
|---|---|
Evidence for Implementation: Management of TB in HIV and Pregnancy.
Topics: Antitubercular Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmiss | 2022 |
Influence of the kidney upon urate homeostasis in health and disease.
Topics: Acute Kidney Injury; Female; Glomerular Filtration Rate; Gout; Homeostasis; Humans; Hypertension; Hy | 1974 |
1 trial available for pyrazinamide and Pregnancy
| Article | Year |
|---|---|
Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Fertilization; Humans; | 2011 |
24 other studies available for pyrazinamide and Pregnancy
| Article | Year |
|---|---|
Exposure to first line anti-tuberculosis drugs in prepubertal age reduces the quality and functional competence of spermatozoa and oocytes in Swiss albino mice.
Topics: Animals; Antitubercular Agents; Cell Nucleus; Ethambutol; Female; Isoniazid; Male; Metaphase; Mice; | 2020 |
Update on the treatment of tuberculosis.
Topics: Antitubercular Agents; Comorbidity; Directly Observed Therapy; Disease Progression; Drug Therapy, Co | 2008 |
[Anti-tuberculosis chemotherapy and management of adverse reactions].
Topics: Aged, 80 and over; Antitubercular Agents; Child; Drug Administration Schedule; Drug Hypersensitivity | 2011 |
A pregnant woman with dyspnoea, fever & decreased vision.
Topics: Adult; Antitubercular Agents; Choroid Diseases; Ethambutol; Female; Humans; Isoniazid; Pregnancy; Pr | 2012 |
ANTI-TUBERCULOSIS THERAPY DURING PREGNANCY.
Topics: Communicable Diseases; Ethionamide; Female; Humans; Infant; Pregnancy; Pregnancy Complications; Preg | 1965 |
Cavitatory pulmonary tuberculosis in a 52-day-old infant.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Asia; Drug Therapy, Combination; Female; Humans; | 2004 |
[Case of pulmonary tuberculosis in late stage of pregnancy].
Topics: Adult; Antitubercular Agents; Cesarean Section; Cross Infection; Drug Therapy, Combination; Ethambut | 2004 |
[Two pregnant immigrant women with tuberculous peritonitis].
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female | 2005 |
Role of latent genital tuberculosis in repeated IVF failure in the Indian clinical setting.
Topics: Adult; Antitubercular Agents; Endometrium; Ethambutol; Female; Fertilization; Fertilization in Vitro | 2006 |
[Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy].
Topics: Adult; Aminosalicylic Acid; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Cy | 2006 |
From the Centers for Disease Control and Prevention. Initial therapy for tuberculosis in the era of multidrug resistance: recommendations of the Advisory Council for the Elimination of Tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambut | 1993 |
Pyrazinamide.
Topics: Female; Humans; Pregnancy; Pyrazinamide; Tuberculosis | 1993 |
CDC recommends four-drug treatment of tuberculosis in multidrug-resistant era.
Topics: Adult; Centers for Disease Control and Prevention, U.S.; Child; Drug Therapy; Drug Therapy, Combinat | 1993 |
Initial therapy for tuberculosis in the era of multidrug resistance. Recommendations of the Advisory Council for the Elimination of Tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambut | 1993 |
Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998. Joint Tuberculosis Committee of the British Thoracic Society.
Topics: Adult; Antitubercular Agents; Child; Child, Preschool; Disease Notification; Drug Administration Sch | 1998 |
[Breast abscess and pregnancy toxemia revealing multidrug resistant tuberculosis].
Topics: Abscess; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Breas | 1999 |
Medical advances with international impact.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotics, Antitubercular; Antitubercular | 1998 |
Complete resolution of cervical spinal tuberculosis with paraplegia in pregnancy.
Topics: Adult; Antitubercular Agents; Cervical Vertebrae; Diagnosis, Differential; Female; Humans; Infant, N | 2002 |
[Treatment of tuberculosis. A care program carried out by a working group in the Swedish Pulmonary Medical Society].
Topics: Ambulatory Care; Antitubercular Agents; Drug Interactions; Ethambutol; Eye Diseases; Female; Follow- | 1976 |
[Therapy of pulmonary tuberculosis].
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Inpatients; Isoniazid; | 1992 |
Reactivation of tuberculous lymphadenitis during pregnancy.
Topics: Adult; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pregnancy; Pregnancy Complications, In | 1992 |
American Thoracic Society. Medical Section of the American Lung Association: Treatment of tuberculosis and tuberculosis infection in adults and children.
Topics: Adult; Age Factors; Blood Cell Count; Blood Urea Nitrogen; Child; Creatinine; Drug Administration Sc | 1986 |
Tuberculosis in an Indochinese refugee camp: epidemiology, management and therapeutic results.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Female | 1985 |
Genetic variations in the acetylation of isoniazid and other drugs.
Topics: Adult; Aminobenzoates; Aminosalicylic Acids; Asian People; Black People; Body Weight; Depression; Fe | 1968 |