pyrazinamide has been researched along with Pleural Effusion in 14 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study intralesional concentrations of isoniazid (INH), rifampicin (RMP) and pyrazinamide (PZA) in tuberculous pleural effusions and psoas abscesses, and to compare these to reference serum values and minimal inhibitory concentration (MIC)." | 9.11 | Penetration of isoniazid, rifampicin and pyrazinamide in tuberculous pleural effusion and psoas abscess. ( Jutte, PC; Rutgers, SR; Uges, DR; Van Altena, R; Van Horn, JR, 2004) |
| "20 Patients of tuberculous pleural effusion were administered a combination of pyrazinamide (30 mg/kg) + isoniazid (300 mg) orally for 7 consecutive days and pyrazinamide was estimated by spectrophotometric method in serum and pleural fluid." | 7.68 | Alteration in the levels of pyrazinamide in pleural fluid following simultaneous administration of prednisoline in patients of tubercular pleural effusion. ( Bhargava, R; Singhal, KC; Wagay, AR, 1990) |
| "To study intralesional concentrations of isoniazid (INH), rifampicin (RMP) and pyrazinamide (PZA) in tuberculous pleural effusions and psoas abscesses, and to compare these to reference serum values and minimal inhibitory concentration (MIC)." | 5.11 | Penetration of isoniazid, rifampicin and pyrazinamide in tuberculous pleural effusion and psoas abscess. ( Jutte, PC; Rutgers, SR; Uges, DR; Van Altena, R; Van Horn, JR, 2004) |
| "To study the efficacy and safety of Category III DOTS treatment (intermittent thrice-weekly rifampicin [RMP], isoniazid [INH] and pyrazinamide for 2 months, followed by RMP and INH for 4 months) under India's Revised National Tuberculosis Control Programme in patients with uncomplicated small unilateral pleural effusion (<1500 ml)." | 3.78 | Outcomes of Category III DOTS treatment in immunocompetent patients with tuberculosis pleural effusion. ( Chauhan, LS; Jain, NK; Mohan, A; Sharma, SK; Solanki, R, 2012) |
| "To test the efficacy of a short-course regimen of 6 months rifampicin and isoniazid supplemented by 2 months initial pyrazinamide (2HRZ-4HR), in the treatment of smear and culture-negative pulmonary tuberculosis and tuberculous pleural effusion in routine clinical practice." | 3.69 | Short-course chemotherapy for tuberculous pleural effusion and culture-negative pulmonary tuberculosis. ( Horsfield, N; McCarthy, OR; Ormerod, LP; Rudd, RM, 1995) |
| "20 Patients of tuberculous pleural effusion were administered a combination of pyrazinamide (30 mg/kg) + isoniazid (300 mg) orally for 7 consecutive days and pyrazinamide was estimated by spectrophotometric method in serum and pleural fluid." | 3.68 | Alteration in the levels of pyrazinamide in pleural fluid following simultaneous administration of prednisoline in patients of tubercular pleural effusion. ( Bhargava, R; Singhal, KC; Wagay, AR, 1990) |
| "Herein, we report a case of peritoneal tuberculosis as paradoxical response while treating tuberculous pleurisy." | 1.37 | [A case of tuberculous peritonitis developed during chemotherapy for tuberculous pleurisy as paradoxical response]. ( Choi, WC; Hong, JH; Jeon, TJ; Kim, SY; Oh, TH; Seo, DD; Seo, JY; Shin, WC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garre, A | 1 |
| Ortega López, N | 1 |
| Pérez, R | 1 |
| Molina, M | 1 |
| Acharya, PR | 1 |
| Sahoo, R | 1 |
| Baliga, P | 1 |
| Khajotia, R | 1 |
| Manthari, K | 1 |
| Kim, SY | 1 |
| Oh, TH | 1 |
| Seo, JY | 1 |
| Hong, JH | 1 |
| Jeon, TJ | 1 |
| Seo, DD | 1 |
| Shin, WC | 1 |
| Choi, WC | 1 |
| Arévalo Gómez, A | 1 |
| Sánchez Vidal, E | 1 |
| Servia Dopazo, M | 1 |
| Llinares Modejar, P | 1 |
| Sharma, SK | 1 |
| Solanki, R | 1 |
| Mohan, A | 1 |
| Jain, NK | 1 |
| Chauhan, LS | 1 |
| Itoh, Y | 1 |
| Ishiguchi, T | 1 |
| Higashimoto, Y | 1 |
| Fujimoto, H | 1 |
| Ohata, M | 1 |
| Itoh, H | 1 |
| Nishiyama, A | 1 |
| Okamura, K | 1 |
| Ono, H | 1 |
| Kawabe, K | 1 |
| Ueda, A | 1 |
| Suruda, T | 1 |
| Jutte, PC | 1 |
| Rutgers, SR | 1 |
| Van Altena, R | 1 |
| Uges, DR | 1 |
| Van Horn, JR | 1 |
| Ormerod, LP | 1 |
| McCarthy, OR | 1 |
| Rudd, RM | 1 |
| Horsfield, N | 1 |
| Köylü, R | 1 |
| Tozkoparan, E | 1 |
| Pabuşçu, Y | 1 |
| Ciftçi, F | 1 |
| Bilgiç, H | 1 |
| Seber, O | 1 |
| Wilkinson, RJ | 1 |
| Vordermeier, HM | 1 |
| Wilkinson, KA | 1 |
| Sjölund, A | 1 |
| Moreno, C | 1 |
| Pasvol, G | 1 |
| Ivanyi, J | 1 |
| Puri, MM | 1 |
| Arora, VK | 1 |
| Wagay, AR | 1 |
| Singhal, KC | 1 |
| Bhargava, R | 1 |
| Greene, ME | 1 |
| Stonehill, RB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnosis of Active Tuberculosis in Endemic Area by Using Enzyme-Linked Immunospot Assay for Gamma-Interferon[NCT00174083] | 200 participants | Observational | 2005-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for pyrazinamide and Pleural Effusion
| Article | Year |
|---|---|
Penetration of isoniazid, rifampicin and pyrazinamide in tuberculous pleural effusion and psoas abscess.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Microbial Sensitivi | 2004 |
13 other studies available for pyrazinamide and Pleural Effusion
| Article | Year |
|---|---|
[Pleural and peritoneal tuberculosis due to Mycobacterium bovis].
Topics: Antitubercular Agents; Combined Modality Therapy; Drug Resistance, Microbial; Drug Therapy, Combinat | 2015 |
An unusual case of a pleural effusion with an abdominal mass.
Topics: Adult; Antitubercular Agents; Drainage; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Ma | 2008 |
An apparently healthy young man with a peculiar-looking chest radiograph.
Topics: Adult; Antibiotics, Antitubercular; Drug Therapy, Combination; Ethambutol; Fever; HIV Seropositivity | 2011 |
[A case of tuberculous peritonitis developed during chemotherapy for tuberculous pleurisy as paradoxical response].
Topics: Adenosine Deaminase; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Hu | 2011 |
[Sternal tumour in a 46-year-old woman].
Topics: Antitubercular Agents; Biopsy; Carcinoma; Combined Modality Therapy; Diagnosis, Differential; Ethamb | 2012 |
Outcomes of Category III DOTS treatment in immunocompetent patients with tuberculosis pleural effusion.
Topics: Adolescent; Adult; Antitubercular Agents; Directly Observed Therapy; Drug Administration Schedule; D | 2012 |
[A case of tuberculosis pleuritis developing contralateral pleural effusion during anti-tuberculosis chemotherapy, falling into chronic respiratory failure].
Topics: Aged; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Humans; Isoniazid; Male; Pl | 2002 |
Short-course chemotherapy for tuberculous pleural effusion and culture-negative pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Fe | 1995 |
Unusual miliary tuberculosis presenting with generalized lymphadenopathy and abdominal involvement.
Topics: Adult; Antitubercular Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol | 1997 |
Peptide-specific T cell response to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy.
Topics: Adolescent; Adult; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; BCG Vaccine; Cell | 1998 |
Contralateral pleural effusion during chemotherapy for tuberculous pleural effusion.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Pleural Effusion | 2000 |
Alteration in the levels of pyrazinamide in pleural fluid following simultaneous administration of prednisoline in patients of tubercular pleural effusion.
Topics: Adolescent; Adult; Aged; Body Fluids; Female; Humans; Male; Middle Aged; Pleura; Pleural Effusion; P | 1990 |
Successive manifestations of tuberculosis in a recalcitrant patient.
Topics: Adult; Aminosalicylic Acids; Communicable Disease Control; Hospitalization; Humans; Isoniazid; Male; | 1973 |