pyrazinamide has been researched along with Pain in 6 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is concluded that the arthralgia was often self-limiting, that aspirin had a small beneficial effect, that allopurinol, in the dosage studied, may have had a slightly deleterious effect, but that it would be worth studying larger dosages of allopurinol because the dosage studied did not affect the serum uric acid concentration." | 2.65 | Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration. ( Allan, WG; Fox, W; Girling, DJ; Horsfall, PA; Nunn, AJ; Plummer, J, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shah, BA | 1 |
| Splain, S | 1 |
| Sarma, GR | 1 |
| Acharyulu, GS | 1 |
| Kannapiran, M | 1 |
| Murthy, PV | 1 |
| Gurumurthy, P | 1 |
| Tripathy, SP | 1 |
| Horsfall, PA | 1 |
| Plummer, J | 1 |
| Allan, WG | 1 |
| Girling, DJ | 1 |
| Nunn, AJ | 1 |
| Fox, W | 1 |
| Lacroix, C | 1 |
| Guyonnaud, C | 1 |
| Chaou, M | 1 |
| Duwoos, H | 1 |
| Lafont, O | 1 |
| Gomi, J | 1 |
| Aoyagi, T | 1 |
2 trials available for pyrazinamide and Pain
| Article | Year |
|---|---|
Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration.
Topics: Adolescent; Adult; Aged; Allopurinol; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female | 1979 |
A controlled clinical trial of small daily doses of rifampicin in the prevention of adverse reactions to the drug in a once-weekly regimen of chemotherapy. A Hong Kong Tuberculosis Treatment Services-British Medical Research Council Investigation.
Topics: Adult; Alanine Transaminase; Antibodies; Ethambutol; Female; Fever; Humans; Jaundice; Male; Middle A | 1974 |
4 other studies available for pyrazinamide and Pain
| Article | Year |
|---|---|
Multifocal osteoarticular tuberculosis.
Topics: Adult; Antitubercular Agents; Bone and Bones; Combined Modality Therapy; Drug Therapy, Combination; | 2005 |
Role of rifampicin in arthralgia induced by pyrazinamide.
Topics: Drug Therapy, Combination; Humans; Joint Diseases; Pain; Pyrazinamide; Rifampin; Tuberculosis, Pulmo | 1983 |
Interaction between allopurinol and pyrazinamide.
Topics: Adult; Allopurinol; Drug Interactions; Drug Therapy, Combination; Humans; Joint Diseases; Male; Pain | 1988 |
Therapeutic effects and side effects of rifampicin administered daily or twice-weekly.
Topics: Adult; Body Weight; Drug Therapy, Combination; Ethambutol; Exanthema; Female; Fever; Follow-Up Studi | 1973 |