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pyrazinamide and Nephritis, Interstitial

pyrazinamide has been researched along with Nephritis, Interstitial in 1 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Pyrazinamide therapy has been associated with dose-dependent hepatotoxicity, hyperuricaemia, arthralgia and arthritis."5.28Tubulointerstitial nephritis associated with pyrazinamide. ( Kauffmann, RH; Sanwikarja, S; Serlie, J; te Velde, J, 1989)
"Pyrazinamide therapy has been associated with dose-dependent hepatotoxicity, hyperuricaemia, arthralgia and arthritis."1.28Tubulointerstitial nephritis associated with pyrazinamide. ( Kauffmann, RH; Sanwikarja, S; Serlie, J; te Velde, J, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanwikarja, S1
Kauffmann, RH1
te Velde, J1
Serlie, J1

Other Studies

1 other study available for pyrazinamide and Nephritis, Interstitial

ArticleYear
Tubulointerstitial nephritis associated with pyrazinamide.
    The Netherlands journal of medicine, 1989, Volume: 34, Issue:1-2

    Topics: Acute Kidney Injury; Adult; Humans; Male; Nephritis, Interstitial; Pyrazinamide; Tuberculosis, Pulmo

1989