pyrazinamide has been researched along with Necrosis in 10 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the 1970s, inclusion of pyrazinamide (PZA) in the drug regimen of tuberculosis (TB) patients for the first 2 mo achieved a drastic reduction of therapy duration." | 3.88 | Impact of immunopathology on the antituberculous activity of pyrazinamide. ( Alvarez Cabrera, N; Blanc, L; Dartois, V; Dias-Freedman, I; Dick, T; Gengenbacher, M; Ioerger, T; Mina, M; O'Brien, P; Podell, BK; Prideaux, B; Sacchettini, J; Sarathy, JP; Savic, RM, 2018) |
| " Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia." | 3.70 | Exercise-induced acute renal failure in a patient with renal hypouricemia. ( Abe, T; Oda, Y; Watanabe, T, 2000) |
| "Pyrazinamide (PZA) is a critical component of current first-line TB therapy." | 1.48 | Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. ( Braunstein, M; Durham, PG; Hayden, JD; Hickey, AJ; Lin, FC; Miller, BK; Montgomery, SA; Rank, L; Welch, JT; Young, EF; Zulauf, KE, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blanc, L | 1 |
| Sarathy, JP | 1 |
| Alvarez Cabrera, N | 1 |
| O'Brien, P | 1 |
| Dias-Freedman, I | 1 |
| Mina, M | 1 |
| Sacchettini, J | 1 |
| Savic, RM | 1 |
| Gengenbacher, M | 1 |
| Podell, BK | 1 |
| Prideaux, B | 1 |
| Ioerger, T | 1 |
| Dick, T | 1 |
| Dartois, V | 1 |
| Montgomery, SA | 1 |
| Young, EF | 1 |
| Durham, PG | 1 |
| Zulauf, KE | 1 |
| Rank, L | 1 |
| Miller, BK | 1 |
| Hayden, JD | 1 |
| Lin, FC | 1 |
| Welch, JT | 1 |
| Hickey, AJ | 1 |
| Braunstein, M | 1 |
| Vazquez-Lopez, F | 1 |
| Fueyo-Casado, A | 1 |
| Gonzalez-Lara, L | 1 |
| Marra, F | 1 |
| Cox, VC | 1 |
| FitzGerald, JM | 1 |
| Moadebi, S | 1 |
| Elwood, RK | 1 |
| Panchabhai, TS | 1 |
| Ambarkhane, SV | 1 |
| Joshi, AS | 1 |
| Samant, BD | 1 |
| Rege, NN | 1 |
| Pilheu, JA | 1 |
| De Salvo, MC | 1 |
| Koch, O | 1 |
| Watanabe, T | 1 |
| Abe, T | 1 |
| Oda, Y | 1 |
| Beckert, W | 3 |
10 other studies available for pyrazinamide and Necrosis
| Article | Year |
|---|---|
Impact of immunopathology on the antituberculous activity of pyrazinamide.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Female; Humans; Microbial Viability; Mycobac | 2018 |
Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis.
Topics: Aerosols; Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Therapy, Comb | 2018 |
Lupus Vulgaris Erythematoides: report of a patient initially misdiagnosed as dermatitis.
Topics: Adrenal Cortex Hormones; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Biopsy; Ca | 2013 |
Successful treatment of multidrug-resistant tuberculosis following drug-induced hepatic necrosis requiring liver transplant.
Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ciprofl | 2004 |
Protective effect of Tinospora cordifolia, Phyllanthus emblica and their combination against antitubercular drugs induced hepatic damage: an experimental study.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; I | 2008 |
Liver alterations in antituberculosis regimens containing pyrazinamide.
Topics: Adolescent; Adult; Aged; Alcoholism; Antitubercular Agents; Cholestasis; Diabetes Complications; Dia | 1981 |
Exercise-induced acute renal failure in a patient with renal hypouricemia.
Topics: Acute Kidney Injury; Child; Creatinine; Exercise; Follow-Up Studies; Humans; Kidney; Kidney Tubules; | 2000 |
[Histological follow-up studies on drug induced liver necroses].
Topics: Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Ethionamide; Follow-Up | 1973 |
[Centrilobular parenchymal necrosis of the liver. A contribution to the knowledge of drug induced lesions of the liver (author's transl)].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Ethionamide; Humans; Liver; Necrosis; Pyrazinamide; | 1973 |
[Centrilobular liver necrosis following antimycobacterial treatment].
Topics: Antitubercular Agents; Biopsy; Chemical and Drug Induced Liver Injury; Ethionamide; Humans; Liver Di | 1971 |