Page last updated: 2024-10-20

pyrazinamide and Malnutrition

pyrazinamide has been researched along with Malnutrition in 5 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Malnutrition: An imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement.

Research Excerpts

ExcerptRelevanceReference
" Inter-individual pharmacokinetic variability and the effect of age, nutritional status, Human immunodeficiency virus (HIV) infection, acetylator genotype may need to be accounted for in striving for the dosages best suited for an individual."2.61Pharmacokinetics of First-Line Anti-Tubercular Drugs. ( Kabra, SK; Lodha, R; Mukherjee, A, 2019)
" No pharmacokinetic data are available from South American children."1.38Pharmacokinetics of anti-tuberculosis drugs in Venezuelan children younger than 16 years of age: supportive evidence for the implementation of revised WHO dosing recommendations. ( Aarnoutse, RE; de Groot, R; de Waard, JH; García, JF; Hermans, PW; López, D; Verhagen, LM; Warris, A, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nansumba, M1
Kumbakumba, E1
Orikiriza, P1
Bastard, M1
Mwanga, JA1
Boum, Y1
de Beaudrap, P1
Bonnet, M1
Mukherjee, A1
Lodha, R1
Kabra, SK1
Verhagen, LM1
López, D1
Hermans, PW1
Warris, A1
de Groot, R1
García, JF1
de Waard, JH1
Aarnoutse, RE1
Graham, SM1
Bell, DJ1
Nyirongo, S1
Hartkoorn, R1
Ward, SA1
Molyneux, EM1
Swaminathan, S1
Padmapriyadarsini, C1
Sukumar, B1
Iliayas, S1
Kumar, SR1
Triveni, C1
Gomathy, P1
Thomas, B1
Mathew, M1
Narayanan, PR1

Reviews

1 review available for pyrazinamide and Malnutrition

ArticleYear
Pharmacokinetics of First-Line Anti-Tubercular Drugs.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:5

    Topics: Age Factors; Antitubercular Agents; Child; Drug Overdose; Ethambutol; Food; Genotype; HIV Infections

2019

Trials

1 trial available for pyrazinamide and Malnutrition

ArticleYear
Nutritional status of persons with HIV infection, persons with HIV infection and tuberculosis, and HIV-negative individuals from southern India.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Mar-15, Volume: 46, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia; Antitubercular Agents; Body Composition; Drug

2008

Other Studies

3 other studies available for pyrazinamide and Malnutrition

ArticleYear
Treatment outcomes and tolerability of the revised WHO anti-tuberculosis drug dosages for children.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 02-01, Volume: 22, Issue:2

    Topics: Antitubercular Agents; Child, Preschool; Cohort Studies; Female; HIV Infections; Humans; Infant; Inf

2018
Pharmacokinetics of anti-tuberculosis drugs in Venezuelan children younger than 16 years of age: supportive evidence for the implementation of revised WHO dosing recommendations.
    Tropical medicine & international health : TM & IH, 2012, Volume: 17, Issue:12

    Topics: Acetyltransferases; Adolescent; Age Factors; Antitubercular Agents; Area Under Curve; Biological Ava

2012
Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Ethambutol; HIV Infections; Humans; Infant;

2006