pyrazinamide has been researched along with Liver Failure, Acute in 5 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, YJ | 1 |
| Wu, G | 1 |
| He, HY | 1 |
| Chen, W | 1 |
| Zou, YS | 1 |
| Li, Q | 1 |
| Zhong, L | 1 |
| Huang, YM | 1 |
| Deng, CL | 1 |
| Kumar, R | 1 |
| Bhatia, V | 1 |
| Khanal, S | 1 |
| Sreenivas, V | 1 |
| Gupta, SD | 1 |
| Panda, SK | 1 |
| Acharya, SK | 1 |
| Whitney, J | 1 |
| Hurwitz, M | 1 |
| Mojtahed, A | 1 |
| Hwang, C | 1 |
| Gallo, A | 1 |
| Durand, F | 1 |
| Pessayre, D | 1 |
| Fournier, M | 1 |
| Belghiti, J | 1 |
| Erlinger, S | 1 |
| Bernuau, J | 1 |
| McKeon, J | 1 |
| Patel, AM | 1 |
1 review available for pyrazinamide and Liver Failure, Acute
| Article | Year |
|---|---|
The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis.
Topics: Antitubercular Agents; Arylamine N-Acetyltransferase; Cytochrome P-450 CYP2E1; Gene Frequency; Genet | 2014 |
4 other studies available for pyrazinamide and Liver Failure, Acute
| Article | Year |
|---|---|
Antituberculosis therapy-induced acute liver failure: magnitude, profile, prognosis, and predictors of outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Female; Hepatitis E; Humans; Indi | 2010 |
Acute liver failure in a pediatric patient with disseminated tuberculosis.
Topics: Antifungal Agents; Antitubercular Agents; Child; Coccidioidomycosis; Drug Therapy, Combination; Etha | 2011 |
Antituberculous therapy and acute liver failure.
Topics: Antitubercular Agents; Drug Therapy, Combination; Hepatic Encephalopathy; Humans; Isoniazid; Liver F | 1995 |
Antituberculous therapy and acute liver failure.
Topics: Adult; Antitubercular Agents; Drug Hypersensitivity; Female; Humans; Isoniazid; Liver Failure, Acute | 1995 |