pyrazinamide has been researched along with Leprosy in 4 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrazinamide in a dose of 1500 mg was given to 63 borderline lepromatous (BL) and lepromatous (LL) leprosy patients on different drug regimens for the initial 2 months of therapy." | 5.06 | Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report. ( Katoch, K; Ramanathan, U; Ramu, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bera, S | 1 |
| Mondal, D | 1 |
| Trindade, MÂ | 1 |
| Miyamoto, D | 1 |
| Benard, G | 1 |
| Sakai-Valente, NY | 1 |
| Vasconcelos, Dde M | 1 |
| Naafs, B | 1 |
| Katoch, K | 1 |
| Ramanathan, U | 1 |
| Ramu, G | 1 |
| Rees, RJ | 1 |
3 reviews available for pyrazinamide and Leprosy
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Leprosy and tuberculosis co-infection: clinical and immunological report of two cases and review of the literature.
Topics: Adult; Brazil; Coinfection; Female; Humans; Immunity, Cellular; Interferon-gamma; Interleukin-12; Is | 2013 |
Leprosy. A preliminary review of the experimental evaluation of drugs for the treatment of leprosy.
Topics: Aminosalicylic Acids; Animals; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethambutol | 1967 |
1 trial available for pyrazinamide and Leprosy
| Article | Year |
|---|---|
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniaz | 1988 |