Page last updated: 2024-10-20

pyrazinamide and Latent Tuberculosis

pyrazinamide has been researched along with Latent Tuberculosis in 14 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Latent Tuberculosis: The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.

Research Excerpts

ExcerptRelevanceReference
"We report the case of a 10-year-old child treated for latent tuberculosis infection (LTBI) with pyrazinamide (PZA) and levofloxacin after contact with a smear-positive multidrug-resistant tuberculosis adult."3.91Drug-Induced Fulminant Hepatitis in a Child Treated for Latent Multidrug-Resistant Tuberculosis With Dual Therapy Combining Pyrazinamide and Levofloxacin. ( Ader, F; Collardeau-Frachon, S; Gillet, Y; Huguet, A; Ohlmann, C, 2019)
"Treatment of latent tuberculosis infection (LTBI) is an important component of tuberculosis (TB) control, and this study updates a previous network meta-analysis of the best LTBI treatment options to inform public health action and programmatic management of LTBI."2.55Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis. ( Beer, N; Harris, RJ; Lipman, MC; Stagg, HR; van der Werf, MJ; Zenner, D, 2017)
"Effective treatment of latent tuberculosis infection (LTBI) is an important component of TB elimination programs."2.50Treatment of latent tuberculosis infection: a network meta-analysis. ( Abubakar, I; Harris, RJ; Lipman, MC; Muñoz, L; Stagg, HR; Zenner, D, 2014)
"The uveitis was treated with local and systemic anti-inflammatory and immunosuppressive therapy in all patients."1.48Effect of Antituberculous Therapy on Uveitis Associated With Latent Tuberculosis. ( Leong, BCS; Lightman, S; McCluskey, PJ; Tomkins-Netzer, O; Zhang, X, 2018)
"This thioridazine exposure was calculated to extinguish all three M."1.39Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners. ( Gumbo, T; Leff, R; Meek, C; Musuka, S; Pasipanodya, J; Siyambalapitiyage Dona, CW; Srivastava, S, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (92.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Hartman-Adams, H1
Gerbo, RM1
George, S1
Khan, MT1
Kaushik, AC1
Bhatti, AI1
Zhang, YJ1
Zhang, S1
Wei, AJ1
Malik, SI1
Wei, DQ1
Marks, SM1
Mase, SR1
Morris, SB1
Zenner, D2
Beer, N1
Harris, RJ2
Lipman, MC2
Stagg, HR2
van der Werf, MJ1
Tomkins-Netzer, O1
Leong, BCS1
Zhang, X1
Lightman, S1
McCluskey, PJ1
Huguet, A1
Ader, F1
Ohlmann, C1
Collardeau-Frachon, S1
Gillet, Y1
Musuka, S1
Srivastava, S1
Siyambalapitiyage Dona, CW1
Meek, C1
Leff, R1
Pasipanodya, J1
Gumbo, T1
Adler-Shohet, FC1
Low, J1
Carson, M1
Girma, H1
Singh, J1
Kumar, N1
Kedarisetty, CK1
Kumar, S1
Khillan, V1
Sarin, SK1
Muñoz, L1
Abubakar, I1
Furukawa, NW1
Haider, MZ1
Allen, SJ1
Carlson, SL1
Lindquist, SW1
Leung, CC1
Rieder, HL1
Lange, C1
Yew, WW1
Duarte, R1
Carvalho, A1
Correia, A1
Lytras, T1
Spala, G1
Bonovas, S1
Panagiotopoulos, T1

Reviews

6 reviews available for pyrazinamide and Latent Tuberculosis

ArticleYear
Marine Natural Products and Drug Resistance in Latent Tuberculosis.
    Marine drugs, 2019, Sep-26, Volume: 17, Issue:10

    Topics: Antitubercular Agents; Biological Products; Drug Resistance; Humans; Latent Tuberculosis; Microbial

2019
Systematic Review, Meta-analysis, and Cost-effectiveness of Treatment of Latent Tuberculosis to Reduce Progression to Multidrug-Resistant Tuberculosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Jun-15, Volume: 64, Issue:12

    Topics: Antitubercular Agents; Cost-Benefit Analysis; Disease Progression; Drug Resistance, Multiple, Bacter

2017
Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis.
    Annals of internal medicine, 2017, Aug-15, Volume: 167, Issue:4

    Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Drug Combinations; Huma

2017
Antitubercular therapy in patients with cirrhosis: challenges and options.
    World journal of gastroenterology, 2014, May-21, Volume: 20, Issue:19

    Topics: Antitubercular Agents; Ethambutol; Humans; Immune System Diseases; Isoniazid; Latent Tuberculosis; L

2014
Treatment of latent tuberculosis infection: a network meta-analysis.
    Annals of internal medicine, 2014, Sep-16, Volume: 161, Issue:6

    Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Th

2014
Treatment of latent infection with Mycobacterium tuberculosis: update 2010.
    The European respiratory journal, 2011, Volume: 37, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Communicable Disease Control; Drug

2011

Other Studies

8 other studies available for pyrazinamide and Latent Tuberculosis

ArticleYear
Tuberculosis: Common Questions and Answers.
    American family physician, 2022, Volume: 106, Issue:3

    Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Latent Tuberculosis; Pyrazinamide; Rifampin; T

2022
Effect of Antituberculous Therapy on Uveitis Associated With Latent Tuberculosis.
    American journal of ophthalmology, 2018, Volume: 190

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination;

2018
Drug-Induced Fulminant Hepatitis in a Child Treated for Latent Multidrug-Resistant Tuberculosis With Dual Therapy Combining Pyrazinamide and Levofloxacin.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:10

    Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Humans; Latent Tuberculosis; Levofloxacin;

2019
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Antipsychotic Agents; Antitubercular Agents; Colony Count, Microbial; Computer Simulation; Drug Admi

2013
Management of latent tuberculosis infection in child contacts of multidrug-resistant tuberculosis.
    The Pediatric infectious disease journal, 2014, Volume: 33, Issue:6

    Topics: Adolescent; Antibiotic Prophylaxis; Antitubercular Agents; Child; Contact Tracing; Humans; Latent Tu

2014
Resistance to First-Line Antituberculosis Drugs in Washington State by Region of Birth and Implications for Latent Tuberculosis Treatment Among Foreign-Born Individuals.
    The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Child, Preschool; Drug Res

2017
Two-month regimen of isoniazid, rifampin and pirazinamid for latent tuberculosis infection.
    Public health, 2012, Volume: 126, Issue:9

    Topics: Adult; Antitubercular Agents; Cohort Studies; Disease Progression; Drug Therapy, Combination; Female

2012
Evaluation of tuberculosis underreporting in Greece through comparison with anti-tuberculosis drug consumption.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Antitubercular Agents; Epidemiological Monitoring; Ethambutol; Greece; Humans; Isoniazid; Latent Tub

2012