pyrazinamide has been researched along with Kidney Diseases in 28 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 8.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 4.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "Hematuria was seen in 7 out of the 16 patients (44%), all of whom were females (58%)." | 1.30 | Hematuria in patients with renal hypouricemia. ( Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A, 1998) |
| "Pyrazinamide (PZA) was used to study the renal handling of hypoxanthine, xanthine and uric acid in 2 normal subjects and in 4 patients with idiopathic renal hypouricemia; one patient was classified as having a postsecretory reabsorption defect, whereas the others were classified as having a presecretory reabsorption defect." | 1.27 | Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia. ( Akaoka, I; Fujimori, S; Itoh, H; Kanbayashi, T; Kaneko, K; Miyashita, H; Nakayama, Y; Oyama, H, 1988) |
| "Uric acid excretion was only slightly affected by pyrazinamide, a drug which suppresses renal tubular uric acid secretion, and by probenecid, a drug which inhibits tubular uric acid reabsorption." | 1.26 | Familial hypouricemia due to isolated renal tubular defect. Attenuated response of uric acid clearance to probenecid and pyrazinamide. ( Benjamin, D; de Vries, A; Pinkhas, J; Sperling, O; Weinberger, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (67.86) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, L | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Bai, D | 1 |
| Yao, J | 1 |
| Yi, L | 1 |
| Ichida, K | 1 |
| Hosoyamada, M | 1 |
| Kimura, H | 1 |
| Takeda, M | 1 |
| Utsunomiya, Y | 1 |
| Hosoya, T | 1 |
| Endou, H | 1 |
| TANI, P | 1 |
| POPPIUS, H | 1 |
| Steele, TH | 2 |
| Rieselbach, RE | 1 |
| Muñoz Sanz, A | 1 |
| García Puig, J | 1 |
| Mateos, F | 1 |
| Barbado, FJ | 1 |
| Hisatome, I | 4 |
| Tanaka, Y | 3 |
| Kotake, H | 2 |
| Kosaka, H | 2 |
| Hirata, N | 1 |
| Fujimoto, Y | 1 |
| Yoshida, A | 3 |
| Shigemasa, C | 2 |
| Mashiba, H | 2 |
| Sato, R | 2 |
| Kato, T | 2 |
| Miyakoda, H | 1 |
| Takami, T | 1 |
| Abe, T | 1 |
| Ogino, K | 3 |
| Mitani, Y | 1 |
| Shimoyama, M | 1 |
| Hiroe, K | 1 |
| Tsuboi, M | 1 |
| Yamamoto, Y | 1 |
| Hamada, N | 1 |
| Manabe, I | 1 |
| Kinugawa, T | 1 |
| Ohtahara, A | 1 |
| Takeda, A | 1 |
| Boss, GR | 1 |
| Seegmiller, JE | 1 |
| Heel, RC | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Frank, M | 1 |
| Many, M | 1 |
| Sperling, O | 2 |
| Benjamin, D | 1 |
| Weinberger, A | 1 |
| Pinkhas, J | 1 |
| de Vries, A | 1 |
| Kawachi, M | 2 |
| Kono, N | 3 |
| Kiyokawa, H | 2 |
| Mineo, I | 2 |
| Nakajima, H | 3 |
| Shimizu, T | 2 |
| Yorifuji, S | 2 |
| Kuwajima, M | 2 |
| Tarui, S | 2 |
| Yamamoto, T | 1 |
| Moriwaki, Y | 1 |
| Takahashi, S | 1 |
| Suda, M | 1 |
| Agbedana, EO | 1 |
| Higashino, K | 1 |
| Ono, A | 1 |
| Nishimura, T | 1 |
| Shichiri, M | 2 |
| Itoh, H | 2 |
| Iwamoto, H | 2 |
| Hirata, Y | 1 |
| Marumo, F | 1 |
| Rauer, S | 1 |
| Schollmeyer, P | 1 |
| Kaneko, K | 2 |
| Fujimori, S | 2 |
| Kanbayashi, T | 2 |
| Akaoka, I | 2 |
| Nakayama, Y | 1 |
| Oyama, H | 1 |
| Miyashita, H | 1 |
| Saito, M | 1 |
| Miyamoto, J | 1 |
| Hasegawa, J | 1 |
| Nakamoto, S | 1 |
| Maeda, M | 1 |
| Kanayama, M | 1 |
| Shiigai, T | 1 |
| Gomi, M | 1 |
| Iida, S | 1 |
| Moriwaki, K | 1 |
| Takeda, E | 1 |
| Kuroda, Y | 1 |
| Ito, M | 2 |
| Toshima, K | 1 |
| Watanabe, T | 1 |
| Naito, E | 1 |
| Yokota, I | 1 |
| Hwang, TJ | 1 |
| Miyao, M | 1 |
| Smetana, SS | 1 |
| Bar-Khayim, Y | 1 |
| Brouard, A | 1 |
| Barreteau, H | 1 |
| Merdjan, H | 1 |
| Paillet, M | 1 |
| Fredj, G | 1 |
| Micoud, M | 1 |
| Mir, MA | 1 |
| Delamore, IW | 1 |
| Simkin, PA | 1 |
| Skeith, MD | 1 |
| Healey, LA | 1 |
3 reviews available for pyrazinamide and Kidney Diseases
| Article | Year |
|---|---|
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human | 1979 |
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia.
Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kine | 1977 |
Control of uric acid excretion.
Topics: Animals; Dogs; Glycine; Gout; Humans; Kidney; Kidney Diseases; Kidney Tubules; Pyrazinamide; Uric Ac | 1971 |
25 other studies available for pyrazinamide and Kidney Diseases
| Article | Year |
|---|---|
[The effect of renal replacement therapy on the plasma concentration of antituberculosis drugs].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Kidney Diseases; Male; Mi | 2015 |
Urate transport via human PAH transporter hOAT1 and its gene structure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Car | 2003 |
SIDE EFFECTS OF AN ANTITUBERCULOUS FIVE-DRUG REGIMEN: ETHIONAMIDE, CYCLOSERINE, PYRAZINAMIDE, VIOMYCIN AND ISONIAZID.
Topics: Amyloidosis; Antitubercular Agents; Cycloserine; Deafness; Drug Hypersensitivity; Duodenal Ulcer; Et | 1963 |
The contribution of residual nephrons within the chronically diseased kidney to urate homeostasis in man.
Topics: Adolescent; Adult; Aged; Asian People; Biological Transport; Black People; Female; Humans; Inulin; K | 1967 |
[Renal physiopathology of uric acid. Pharmacologic study].
Topics: Humans; Kidney Diseases; Kidney Tubules; Probenecid; Pyrazinamide; Uric Acid; Uricosuric Agents | 1982 |
Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate.
Topics: Benzbromarone; Citrates; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Ki | 1993 |
Renal hypouricemia with both drug-insensitive secretion and defective reabsorption of urate: a novel type of renal hypouricemia.
Topics: Adult; Creatinine; Drug Resistance; Extracellular Space; Furosemide; Humans; Inosine; Kidney Disease | 1993 |
Hematuria in patients with renal hypouricemia.
Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Disease | 1998 |
Familial renal hypouricaemia: two additional cases with uric acid lithiasis.
Topics: Adult; Calcium; Humans; Jews; Kidney Calculi; Kidney Diseases; Male; Pedigree; Probenecid; Pyrazinam | 1979 |
Familial hypouricemia due to isolated renal tubular defect. Attenuated response of uric acid clearance to probenecid and pyrazinamide.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules, Proximal; Probenecid; | 1977 |
Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.
Topics: Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; P | 1992 |
Two cases in whom pyrazinamide does not inhibit the uricosuric action of benzbromarone.
Topics: Adult; Benzbromarone; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Kidney; Kidney D | 1992 |
Renal hypouricemia associated with hyperoxypurinemia due to decreased renal excretion of oxypurines: a new defect in renal purine transport.
Topics: Diet; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Tubules; Kinetics; Male; Middle A | 1991 |
Renal tubular hypouricemia: evidence for defect of both secretion and reabsorption.
Topics: Aged; Aspirin; Creatinine; Furosemide; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubule | 1990 |
Evaluation of urate renal handling in humans.
Topics: Adult; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Male; Probenecid; Pyrazinamide; Uric | 1989 |
Renal handling of hypoxanthine and xanthine in normal subjects and in cases of idiopathic renal hypouricemia.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hypoxanthines; Kidney; Kidney Diseases; Male; M | 1989 |
Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia.
Topics: Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Kidney Diseases; Male; Middle Aged; Pyra | 1988 |
Renal hypouricemia due to an isolated renal defect of urate transport.
Topics: Adult; Benzbromarone; Humans; Kidney; Kidney Diseases; Male; Pyrazinamide; Uric Acid | 1988 |
Hypouricemia due to subtotal defect in the urate transport.
Topics: Adult; Biological Transport; Female; Humans; Kidney Diseases; Kidney Tubules; Probenecid; Pyrazinami | 1987 |
Familial renal hypouricemia with intact reabsorption of uric acid.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Tubules; Male; Middle Aged; Probenecid; Pyrazinamide; | 1987 |
Hereditary renal hypouricemia in children.
Topics: Benzbromarone; Child; Child, Preschool; Creatinine; Humans; Kidney Diseases; Kidney Tubules; Metabol | 1985 |
Hypouricemia due to renal tubular defect. A study with the probenecid-pyrazinamide test.
Topics: Adult; Calcium; Creatinine; Female; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; | 1985 |
Rapid determination of pyrazinamide in biological fluids by high-performance liquid chromatography.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Kidney Diseases; Kinetics; Pyra | 1985 |
Hypouricaemia and proximal renal tubular dysfunction in acute myeloid leukaemia.
Topics: Amino Acids; Calcium; Creatinine; Cytarabine; Daunorubicin; Female; Humans; Hydrogen-Ion Concentrati | 1974 |
Suppression of uric acid secretion in a patient with renal hypouricemia.
Topics: Circadian Rhythm; Creatinine; Female; Humans; Kidney Diseases; Middle Aged; Probenecid; Purine-Pyrim | 1974 |