pyrazinamide has been researched along with Joint Diseases in 9 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Joint Diseases: Diseases involving the JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is concluded that the arthralgia was often self-limiting, that aspirin had a small beneficial effect, that allopurinol, in the dosage studied, may have had a slightly deleterious effect, but that it would be worth studying larger dosages of allopurinol because the dosage studied did not affect the serum uric acid concentration." | 2.65 | Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration. ( Allan, WG; Fox, W; Girling, DJ; Horsfall, PA; Nunn, AJ; Plummer, J, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BEK, E | 1 |
| Abraham, S | 1 |
| Mitchell, A | 1 |
| Cope, A | 1 |
| Sarma, GR | 1 |
| Acharyulu, GS | 1 |
| Kannapiran, M | 1 |
| Murthy, PV | 1 |
| Gurumurthy, P | 1 |
| Tripathy, SP | 1 |
| Ishiguro, S | 1 |
| Jenner, PJ | 1 |
| Ellard, GA | 1 |
| Allan, WG | 2 |
| Singh, D | 1 |
| Girling, DJ | 2 |
| Nunn, AJ | 2 |
| Horsfall, PA | 1 |
| Plummer, J | 1 |
| Fox, W | 1 |
| Mignot, P | 1 |
| Dumas, R | 1 |
| Lavarenne, J | 1 |
| Molina, C | 1 |
| Lacroix, C | 1 |
| Guyonnaud, C | 1 |
| Chaou, M | 1 |
| Duwoos, H | 1 |
| Lafont, O | 1 |
2 trials available for pyrazinamide and Joint Diseases
| Article | Year |
|---|---|
Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration.
Topics: Adolescent; Adult; Aged; Allopurinol; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female | 1979 |
A controlled clinical trial of 3- and 5-month regimens in the treatment of sputum-positive pulmonary tuberculosis in South India. Tuberculosis Research Centre, Madras, and National Tuberculosis Institute, Bangalore.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as | 1986 |
7 other studies available for pyrazinamide and Joint Diseases
| Article | Year |
|---|---|
[INTOLERANCE AND TOXICITY OF SUBSTITUTE ANTIBACTERIAL DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Chemical and Drug Induced Liver In | 1963 |
Anti-tuberculous therapy-induced crystal arthropathy.
Topics: Aged; Antitubercular Agents; Crystallization; Ethambutol; Female; Humans; Joint Diseases; Pyrazinami | 2006 |
Role of rifampicin in arthralgia induced by pyrazinamide.
Topics: Drug Therapy, Combination; Humans; Joint Diseases; Pain; Pyrazinamide; Rifampin; Tuberculosis, Pulmo | 1983 |
[Arthralgia and uricemia produced by pyrazinamide].
Topics: Adolescent; Adult; Aged; Female; Humans; Joint Diseases; Male; Middle Aged; Pyrazinamide; Tuberculos | 1982 |
Serum uric acid concentrations and arthralgia among patients treated with pyrazinamide-containing regimens in Hong Kong and Singapore.
Topics: Humans; Joint Diseases; Pyrazinamide; Tuberculosis, Pulmonary; Uric Acid | 1981 |
[Antituberculous chemotherapy: a constraining adverse effect of pyrazinamide].
Topics: Adult; Drug Therapy, Combination; Headache; Humans; Joint Diseases; Male; Paresthesia; Pyrazinamide; | 1988 |
Interaction between allopurinol and pyrazinamide.
Topics: Adult; Allopurinol; Drug Interactions; Drug Therapy, Combination; Humans; Joint Diseases; Male; Pain | 1988 |