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pyrazinamide and Infections, Mycobacterium

pyrazinamide has been researched along with Infections, Mycobacterium in 25 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Research Excerpts

ExcerptRelevanceReference
"Substituted pyrazinoic acid esters have previously been reported to have in vitro activity against Mycobacterium avium and Mycobacterium kansasii as well as Mycobacterium tuberculosis."3.69Quantitative structure-activity relationships for the in vitro antimycobacterial activity of pyrazinoic acid esters. ( Bergmann, KE; Cynamon, MH; Welch, JT, 1996)
"Pyrazinamide was only bacteriostatic in macrophages but weakly bactericidal during the first day of exposure in vitro."1.28Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254. ( Dhillon, J; Mitchison, DA, 1989)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's5 (20.00)18.2507
2000's6 (24.00)29.6817
2010's3 (12.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Suga, S1
Mukai, Y1
Ishikawa, S1
Yoshida, S1
Paudel, S1
Wada, T1
Patsche, CB1
Svensson, E1
Wejse, C1
Gravet, A1
Souillard, N1
Habermacher, J1
Moser, A1
Lohmann, C1
Schmitt, F1
Delarbre, JM1
Ricart, JM1
Martín, JM1
Renau, A1
Pérez, J1
Cabria, F1
Torres, MV1
García-Cía, JI1
Dominguez-Garrido, MN1
Esteban, J1
Jimenez, MS1
Benito González, JJ1
Benito González, F1
Santa Cruz Ruiz, S1
Gómez González, JL1
Coscarón Blanco, E1
Cordero Sánchez, M1
del Cañizo Alvarez, A1
SALIBA, A1
BEATTY, OA1
PFUETZE, KH1
PYLE, MM1
CORPE, RF1
CHAVES, AD1
Scholze, A1
Loddenkemper, C1
Grünbaum, M1
Moosmayer, I1
Offermann, G1
Tepel, M1
Göpel, B1
Götte, K1
Delaney, V1
Sumrani, N1
Hong, JH1
Sommer, B1
Bergmann, KE1
Cynamon, MH1
Welch, JT1
Fisher, M1
Tomlinson, DR1
Coker, RJ1
Schultsz, C1
Kuijper, EJ1
van Soolingen, D1
Prins, JM1
Arslan, H1
Oner-Eyüboglu, F1
Kalpaklioglu, F1
Gürdogan, K1
Akçay, S1
Demirag, A1
Haberal, M1
Niemann, S1
Richter, E1
Rüsch-Gerdes, S1
Bhalla, RK1
Jones, TM1
Rothburn, MM1
Swift, AC1
Heap, BJ1
Dhillon, J1
Mitchison, DA1
Snider, DE1
Farer, LS1
Toida, I2
Rauscher, CR1
Kerby, G1
Ruth, WE1

Reviews

2 reviews available for pyrazinamide and Infections, Mycobacterium

ArticleYear
Cervical lymphadenitis caused by Mycobacterium lentiflavum.
    The Pediatric infectious disease journal, 2002, Volume: 21, Issue:6

    Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Humans; Infant; Isoniazid; Lymph Nodes; Male

2002
[Procedure in case of suspected mycobacterial infection of lymph nodes of the neck. 2. Therapy].
    Laryngo- rhino- otologie, 2005, Volume: 84, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Disease Notificati

2005

Other Studies

23 other studies available for pyrazinamide and Infections, Mycobacterium

ArticleYear
INTENSIVE TREATMENT OF A CAPTIVE BORNEAN ELEPHANT (
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2021, Volume: 51, Issue:4

    Topics: Administration, Rectal; Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; E

2021
Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 26

    Topics: Aged; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Therapy, Combination;

2014
[Culture and susceptibility testing of mycobacteria with VersaTREK].
    Pathologie-biologie, 2011, Volume: 59, Issue:1

    Topics: Algorithms; Antitubercular Agents; Automation; Bacteriological Techniques; Culture Media; Ethambutol

2011
Granulomatous lesion on the face successfully treated with antitubercular therapy.
    Dermatology online journal, 2010, Sep-15, Volume: 16, Issue:9

    Topics: Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Et

2010
[Tuberculous otitis media. Report of 3 cases].
    Anales otorrinolaringologicos ibero-americanos, 2003, Volume: 30, Issue:1

    Topics: Adult; Aged; Amoxicillin; Antitubercular Agents; Cerebrospinal Fluid Otorrhea; Drug Combinations; Ea

2003
DRUG RESISTANT MYCOBACTERIAL INFECTION AND ITS RESPONSE TO TREATMENT.
    The Journal of the Kentucky Medical Association, 1963, Volume: 61

    Topics: Cycloserine; Drug Resistance; Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium; Mycobact

1963
RECENT ADVANCES IN TREATMENT OF ORGAN TUBERCULOSIS.
    JAMA, 1964, Mar-14, Volume: 187

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Child; Cycloserine; Ethionamide; I

1964
CLINICAL ASPECTS, MEDICAL AND SURGICAL, IN THE MANAGEMENT OF BATTEY-TYPE PULMONARY DISEASE.
    Diseases of the chest, 1964, Volume: 45

    Topics: Bronchiectasis; Calcification, Physiologic; Drug Resistance; Drug Resistance, Microbial; Epidemiolog

1964
PULMONARY TUBERCULOSIS.
    Modern treatment, 1964, Volume: 1

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Child; Cycloserine; Drug Resista

1964
Cutaneous Mycobacterium abscessus infection after kidney transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:8

    Topics: Anti-Bacterial Agents; Clarithromycin; Humans; Kidney Transplantation; Male; Middle Aged; Mycobacter

2005
Mycobacterial infections in renal allograft recipients.
    Transplantation proceedings, 1993, Volume: 25, Issue:3

    Topics: Drug Therapy, Combination; Ethambutol; HIV Seropositivity; Humans; Immunosuppressive Agents; Isoniaz

1993
Quantitative structure-activity relationships for the in vitro antimycobacterial activity of pyrazinoic acid esters.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Esters; Humans; Microbial Sensitivity

1996
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
    International journal of STD & AIDS, 1996, Volume: 7, Issue:4

    Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitu

1996
Disseminated infection due to multidrug-resistant Mycobacterium bovis in a patient who was seropositive for human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23, Issue:4

    Topics: Antibiotics, Antitubercular; Antitubercular Agents; DNA Fingerprinting; DNA, Bacterial; Drug Resista

1996
Mycobacterial infections in solid organ transplant recipients.
    Transplantation proceedings, 1999, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Follow-Up S

1999
Differentiation among members of the Mycobacterium tuberculosis complex by molecular and biochemical features: evidence for two pyrazinamide-susceptible subtypes of M. bovis.
    Journal of clinical microbiology, 2000, Volume: 38, Issue:1

    Topics: Animals; Antitubercular Agents; Bacterial Typing Techniques; Cattle; Drug Resistance, Microbial; Hum

2000
Tuberculous otitis media -- a diagnostic dilemma.
    Auris, nasus, larynx, 2001, Volume: 28, Issue:3

    Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ear Diseases; Faci

2001
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
    Tubercle, 1989, Volume: 70, Issue:3

    Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Myco

1989
Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:8

    Topics: Animals; Antitubercular Agents; Culture Media; Hydrogen-Ion Concentration; In Vitro Techniques; Ison

1989
Package inserts for antituberculosis drugs and tuberculins.
    The American review of respiratory disease, 1985, Volume: 131, Issue:6

    Topics: Antitubercular Agents; Child; Child, Preschool; Contraceptives, Oral; Drug Interactions; Drug Labeli

1985
Pyrazinamide deamidase in tuberculous infection.
    The American review of respiratory disease, 1973, Volume: 107, Issue:4

    Topics: Amidohydrolases; Animals; Antigens; BCG Vaccine; Enzyme Repression; Female; Glycolipids; Liver; Male

1973
Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host.
    The American review of respiratory disease, 1973, Volume: 107, Issue:4

    Topics: Animals; Drug Resistance, Microbial; Isoniazid; Liver; Male; Mice; Mycobacterium Infections; Mycobac

1973
A ten-year clinical experience with Mycobacterium kansasii.
    Chest, 1974, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Antitubercular Agents; Child; Cycloserine; Ethambutol

1974