pyrazinamide has been researched along with Hypoxia in 4 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "tuberculosis have striking similarities, such as necrosis, mineralization, and hypoxia, to natural infections in humans." | 1.34 | Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910. ( Aly, S; Andries, K; Basaraba, RJ; Cantarero, L; Ehlers, S; Hoff, D; Lenaerts, AJ; Orme, IM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iacobino, A | 1 |
| Giannoni, F | 1 |
| Pardini, M | 1 |
| Piccaro, G | 1 |
| Fattorini, L | 1 |
| Harper, J | 1 |
| Skerry, C | 1 |
| Davis, SL | 1 |
| Tasneen, R | 1 |
| Weir, M | 1 |
| Kramnik, I | 1 |
| Bishai, WR | 1 |
| Pomper, MG | 1 |
| Nuermberger, EL | 1 |
| Jain, SK | 1 |
| Lenaerts, AJ | 1 |
| Hoff, D | 1 |
| Aly, S | 1 |
| Ehlers, S | 1 |
| Andries, K | 1 |
| Cantarero, L | 1 |
| Orme, IM | 1 |
| Basaraba, RJ | 1 |
| Chaplin, DJ | 1 |
| Trotter, MJ | 1 |
| Skov, KA | 1 |
| Horsman, MR | 1 |
4 other studies available for pyrazinamide and Hypoxia
| Article | Year |
|---|---|
The Combination Rifampin-Nitazoxanide, but Not Rifampin-Isoniazid-Pyrazinamide-Ethambutol, Kills Dormant Mycobacterium tuberculosis in Hypoxia at Neutral pH.
Topics: Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Hydrogen-Io | 2019 |
Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions.
Topics: Animals; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Fluoroquinolones; Gene Expres | 2012 |
Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Diarylquinolin | 2007 |
Modification of tumour radiation response in vivo by the benzamide analogue pyrazinamide.
Topics: Animals; Cell Survival; Cells, Cultured; Hypoxia; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neopl | 1990 |