pyrazinamide has been researched along with Hepatolenticular Degeneration in 2 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilson, DM | 2 |
| Goldstein, NP | 1 |
| Goldstein, P | 1 |
2 other studies available for pyrazinamide and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Renal urate excretion in patients with Wilson's disease.
Topics: Arginine; Depression, Chemical; Glomerular Filtration Rate; Glutamine; Hepatolenticular Degeneration | 1973 |
Evidence for a urate reabsorptive defect in patients with Wilson's disease.
Topics: Arginine; Follow-Up Studies; Glomerular Filtration Rate; Glutamine; Hepatolenticular Degeneration; H | 1974 |