Page last updated: 2024-10-20

pyrazinamide and Hansen Disease

pyrazinamide has been researched along with Hansen Disease in 4 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Research Excerpts

ExcerptRelevanceReference
"Pyrazinamide in a dose of 1500 mg was given to 63 borderline lepromatous (BL) and lepromatous (LL) leprosy patients on different drug regimens for the initial 2 months of therapy."5.06Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report. ( Katoch, K; Ramanathan, U; Ramu, G, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bera, S1
Mondal, D1
Trindade, MÂ1
Miyamoto, D1
Benard, G1
Sakai-Valente, NY1
Vasconcelos, Dde M1
Naafs, B1
Katoch, K1
Ramanathan, U1
Ramu, G1
Rees, RJ1

Reviews

3 reviews available for pyrazinamide and Hansen Disease

ArticleYear
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Leprosy and tuberculosis co-infection: clinical and immunological report of two cases and review of the literature.
    The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:2

    Topics: Adult; Brazil; Coinfection; Female; Humans; Immunity, Cellular; Interferon-gamma; Interleukin-12; Is

2013
Leprosy. A preliminary review of the experimental evaluation of drugs for the treatment of leprosy.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1967, Volume: 61, Issue:4

    Topics: Aminosalicylic Acids; Animals; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethambutol

1967

Trials

1 trial available for pyrazinamide and Hansen Disease

ArticleYear
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1988, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniaz

1988