pyrazinamide has been researched along with Granuloma in 16 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Noncaseating granulomatous hepatitis may be caused by a variety of drugs, but we have not found, by computer search of the literature, a previous describe of granulomatous hepatitis associated with pyrazinamide." | 7.69 | Pyrazinamide-induced granulomatous hepatitis. ( Buyanowsky, G; Dan, M; Knobel, B; Zaidel, L, 1997) |
| "Noncaseating granulomatous hepatitis may be caused by a variety of drugs, but we have not found, by computer search of the literature, a previous describe of granulomatous hepatitis associated with pyrazinamide." | 3.69 | Pyrazinamide-induced granulomatous hepatitis. ( Buyanowsky, G; Dan, M; Knobel, B; Zaidel, L, 1997) |
| " This is despite the availability of antibiotics that have good activity against Mycobacterium tuberculosis in vitro and favorable pharmacokinetic profiles in plasma." | 1.38 | Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions. ( Barry, CE; Dartois, V; Goh, A; Kern, S; Kjellsson, MC; Low, KM; Pillai, G; Via, LE; Weiner, D, 2012) |
| " Drug therapy either alone or in combination with BCG, was more effective at lessening clinical disease and lesion severity compared to control animals or those receiving BCG alone." | 1.38 | Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis. ( Ackart, D; Basaraba, RJ; Caraway, ML; Hascall-Dove, L; Henao-Tamayo, M; Ordway, DJ; Orme, EA; Orme, IM; Shang, S; Shanley, CA, 2012) |
| "Paragonimiasis is a food-borne zoonosis caused by a trematode of the genus Paragonimus(1,2)." | 1.37 | [Pulmonary paragonimiasis]. ( Fortes-Alen, J; Gómez-Escolar, PF; Gómez-Seco, J; Presa-Abos, T; Rodríguez-Guzmán, MJ; Rodríguez-Nieto, MJ, 2011) |
| "tuberculosis have striking similarities, such as necrosis, mineralization, and hypoxia, to natural infections in humans." | 1.34 | Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910. ( Aly, S; Andries, K; Basaraba, RJ; Cantarero, L; Ehlers, S; Hoff, D; Lenaerts, AJ; Orme, IM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Murthy, SI | 1 |
| Rathi, VM | 1 |
| Tyagi, M | 1 |
| Mishra, DK | 1 |
| Pappuru, RR | 1 |
| Hernandez, J | 1 |
| Ashley, D | 1 |
| Cao, R | 1 |
| Abrahem, R | 1 |
| Nguyen, T | 1 |
| To, K | 1 |
| Yegiazaryan, A | 1 |
| Akinwale David, A | 1 |
| Kumar Tiwari, R | 1 |
| Venketaraman, V | 1 |
| Goel, N | 1 |
| Kumar, V | 1 |
| Arora, S | 1 |
| Ghosh, B | 1 |
| Ricart, JM | 1 |
| Martín, JM | 1 |
| Renau, A | 1 |
| Pérez, J | 1 |
| Gómez-Seco, J | 1 |
| Rodríguez-Guzmán, MJ | 1 |
| Rodríguez-Nieto, MJ | 1 |
| Gómez-Escolar, PF | 1 |
| Presa-Abos, T | 1 |
| Fortes-Alen, J | 1 |
| Consunji-Araneta, R | 1 |
| Higgins, R | 1 |
| Qing, G | 1 |
| Bouhasan, L | 1 |
| Kjellsson, MC | 1 |
| Via, LE | 1 |
| Goh, A | 1 |
| Weiner, D | 1 |
| Low, KM | 1 |
| Kern, S | 1 |
| Pillai, G | 1 |
| Barry, CE | 1 |
| Dartois, V | 1 |
| Harper, J | 1 |
| Skerry, C | 1 |
| Davis, SL | 1 |
| Tasneen, R | 1 |
| Weir, M | 1 |
| Kramnik, I | 2 |
| Bishai, WR | 1 |
| Pomper, MG | 1 |
| Nuermberger, EL | 1 |
| Jain, SK | 1 |
| Shang, S | 1 |
| Shanley, CA | 1 |
| Caraway, ML | 1 |
| Orme, EA | 1 |
| Henao-Tamayo, M | 1 |
| Hascall-Dove, L | 1 |
| Ackart, D | 1 |
| Orme, IM | 2 |
| Ordway, DJ | 1 |
| Basaraba, RJ | 3 |
| Driver, ER | 1 |
| Ryan, GJ | 1 |
| Hoff, DR | 1 |
| Irwin, SM | 1 |
| Lenaerts, AJ | 2 |
| Basu, S | 1 |
| Mittal, R | 1 |
| Balne, PK | 1 |
| Sharma, S | 1 |
| Fonollosa, A | 1 |
| Segura, A | 1 |
| Giralt, J | 1 |
| Garcia-Arumi, J | 1 |
| Hoff, D | 1 |
| Aly, S | 1 |
| Ehlers, S | 1 |
| Andries, K | 1 |
| Cantarero, L | 1 |
| Pilheu, JA | 1 |
| De Salvo, MC | 1 |
| Koch, O | 1 |
| Brmbolić, BJ | 1 |
| Boricić, I | 1 |
| Salemović, DR | 1 |
| Jevtović, DL | 1 |
| Ranin, JT | 1 |
| Begić-Janeva, A | 1 |
| Knobel, B | 1 |
| Buyanowsky, G | 1 |
| Dan, M | 1 |
| Zaidel, L | 1 |
16 other studies available for pyrazinamide and Granuloma
| Article | Year |
|---|---|
Presumed Intraocular Tuberculosis Manifesting as Unilateral Iris Granuloma.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Granuloma; Humans; Iris Disease | 2020 |
Cyclic Peptide [R
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Autophagy; Cytokines; Drug Therapy, Combinatio | 2020 |
Massive choroidal granuloma as the presenting feature of disseminated tuberculosis in immunocompetent patients.
Topics: Adolescent; Adult; Antitubercular Agents; Choroid Diseases; Drug Combinations; Ethambutol; Female; G | 2018 |
Granulomatous lesion on the face successfully treated with antitubercular therapy.
Topics: Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Et | 2010 |
[Pulmonary paragonimiasis].
Topics: Adult; Animals; Anthelmintics; Antitubercular Agents; Caulobacteraceae; Delayed Diagnosis; Ecuador; | 2011 |
Tuberculous damaged lung in a child.
Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Granuloma; Humans; Ison | 2011 |
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions.
Topics: Animals; Antitubercular Agents; Aza Compounds; Biological Availability; Disease Models, Animal; Drug | 2012 |
Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions.
Topics: Animals; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Fluoroquinolones; Gene Expres | 2012 |
Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis.
Topics: Animals; BCG Vaccine; Combined Modality Therapy; Female; Granuloma; Guinea Pigs; Isoniazid; Lung; My | 2012 |
Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Granuloma; Metronidazole; Mice; Mice, Inbred | 2012 |
Intraretinal tuberculosis.
Topics: Administration, Oral; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Granuloma | 2012 |
Tuberculous uveitis after treatment with etanercept.
Topics: Antirheumatic Agents; Antitubercular Agents; Aqueous Humor; Arthritis, Rheumatoid; Drug Therapy, Com | 2007 |
Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Diarylquinolin | 2007 |
Liver alterations in antituberculosis regimens containing pyrazinamide.
Topics: Adolescent; Adult; Aged; Alcoholism; Antitubercular Agents; Cholestasis; Diabetes Complications; Dia | 1981 |
Focal tuberculosis of the liver with local hemorrhage in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ethambutol; Granuloma; Histocytochemistry; Homosexuality, | 1996 |
Pyrazinamide-induced granulomatous hepatitis.
Topics: Antitubercular Agents; Biopsy; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Gr | 1997 |