pyrazinamide has been researched along with Genetic Predisposition in 7 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case-control study including Caucasian patients with tuberculosis (TB) treated with isoniazid, rifampicin and pyrazinamide." | 3.77 | N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in Caucasians. ( Agúndez, JA; Botana-Rial, M; Constenla, L; Fernández-Villar, A; Leiro-Fernandez, V; Valverde, D; Vázquez-Gallardo, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, H | 1 |
| Wu, T | 1 |
| Jiao, L | 1 |
| Wu, Q | 1 |
| Zhao, Z | 1 |
| Song, J | 1 |
| Liu, T | 1 |
| Lv, Y | 1 |
| Lu, X | 1 |
| Ying, B | 1 |
| Wang, Y | 2 |
| Xiang, X | 1 |
| Wu, SQ | 2 |
| Chen, G | 2 |
| Zhang, MM | 2 |
| Wang, MG | 1 |
| Wang, FJ | 1 |
| Sandford, AJ | 1 |
| He, JQ | 2 |
| Feng, M | 1 |
| Wu, JC | 1 |
| Ji, GY | 1 |
| Liu, QQ | 1 |
| Sheng, YJ | 1 |
| Wu, G | 1 |
| He, HY | 1 |
| Chen, W | 1 |
| Zou, YS | 1 |
| Li, Q | 1 |
| Zhong, L | 1 |
| Huang, YM | 1 |
| Deng, CL | 1 |
| Lee, SW | 1 |
| Chung, LS | 1 |
| Huang, HH | 1 |
| Chuang, TY | 1 |
| Liou, YH | 1 |
| Wu, LS | 1 |
| Leiro-Fernandez, V | 1 |
| Valverde, D | 2 |
| Vázquez-Gallardo, R | 1 |
| Botana-Rial, M | 1 |
| Constenla, L | 2 |
| Agúndez, JA | 1 |
| Fernández-Villar, A | 2 |
| Leiro, V | 1 |
| Vázquez, R | 1 |
| Piñeiro, L | 1 |
| González-Quintela, A | 1 |
1 review available for pyrazinamide and Genetic Predisposition
| Article | Year |
|---|---|
The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis.
Topics: Antitubercular Agents; Arylamine N-Acetyltransferase; Cytochrome P-450 CYP2E1; Gene Frequency; Genet | 2014 |
1 trial available for pyrazinamide and Genetic Predisposition
| Article | Year |
|---|---|
Association of UGT2B7 polymorphisms with risk of induced liver injury by anti-tuberculosis drugs in Chinese Han.
Topics: Adult; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; Drug Therapy, Co | 2017 |
5 other studies available for pyrazinamide and Genetic Predisposition
| Article | Year |
|---|---|
Association of ABCC Gene Polymorphism With Susceptibility to Antituberculosis Drug-Induced Hepatotoxicity in Western Han Patients With Tuberculosis.
Topics: Adult; Alanine Transaminase; Antitubercular Agents; Asian People; ATP-Binding Cassette Transporters; | 2020 |
Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population.
Topics: Adult; Alleles; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; Cytochr | 2017 |
NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and D | 2010 |
N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in Caucasians.
Topics: Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Case-Control Studies; Chemical and Drug | 2011 |
Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population.
Topics: Adult; Alanine Transaminase; Antitubercular Agents; Aspartate Aminotransferases; Case-Control Studie | 2008 |