Page last updated: 2024-10-20

pyrazinamide and Gaucher Disease

pyrazinamide has been researched along with Gaucher Disease in 1 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dulgar, O1
Eskazan, AE1
Ersen, E1
Demiroz, AS1
Turna, A1
Oz, B1
Tuzuner, N1

Other Studies

1 other study available for pyrazinamide and Gaucher Disease

ArticleYear
Pleural tuberculosis in a patient with untreated type 1 Gaucher disease.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:1

    Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Gaucher Disease; Humans; Isonia

2016