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pyrazinamide and Drug Overdose

pyrazinamide has been researched along with Drug Overdose in 3 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"We report three patients who experienced hepatotoxic reactions in association with acetaminophen ingestion while undergoing treatment for active tuberculosis with isoniazid, rifampin, and other agents."7.69Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis. ( Nelson, SD; Nolan, CM; Sandblom, RE; Slattery, JT; Thummel, KE, 1994)
"We report three patients who experienced hepatotoxic reactions in association with acetaminophen ingestion while undergoing treatment for active tuberculosis with isoniazid, rifampin, and other agents."3.69Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis. ( Nelson, SD; Nolan, CM; Sandblom, RE; Slattery, JT; Thummel, KE, 1994)
" Inter-individual pharmacokinetic variability and the effect of age, nutritional status, Human immunodeficiency virus (HIV) infection, acetylator genotype may need to be accounted for in striving for the dosages best suited for an individual."2.61Pharmacokinetics of First-Line Anti-Tubercular Drugs. ( Kabra, SK; Lodha, R; Mukherjee, A, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mukherjee, A1
Lodha, R1
Kabra, SK1
Pawlas, N1
Miskiewicz, Ł1
Motyka, S1
Nowakowski, R1
Pajak, J1
Celiński, R1
Kłopotowski, T1
Nolan, CM1
Sandblom, RE1
Thummel, KE1
Slattery, JT1
Nelson, SD1

Reviews

1 review available for pyrazinamide and Drug Overdose

ArticleYear
Pharmacokinetics of First-Line Anti-Tubercular Drugs.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:5

    Topics: Age Factors; Antitubercular Agents; Child; Drug Overdose; Ethambutol; Food; Genotype; HIV Infections

2019

Other Studies

2 other studies available for pyrazinamide and Drug Overdose

ArticleYear
Fatal suicidal poisoning with antituberculosis agents with ST elevation and acute coronary syndrome symptoms--a case report.
    Przeglad lekarski, 2013, Volume: 70, Issue:8

    Topics: Acute Coronary Syndrome; Antitubercular Agents; Drug Overdose; Echocardiography; Ethanol; Fatal Outc

2013
Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis.
    Chest, 1994, Volume: 105, Issue:2

    Topics: Acetaminophen; Adult; Capreomycin; Ciprofloxacin; Drug Combinations; Drug Overdose; Ethambutol; Fema

1994