pyrazinamide and Drug Hypersensitivity
pyrazinamide has been researched along with Drug Hypersensitivity in 39 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" Subjects who experienced hypersensitivity reactions, including maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS), to first-line anti-tuberculosis medications (isoniazid [INH], ethambutol [EMB], rifampin [RFP], and pyrazinamide [PZA]) were enrolled." | 3.91 | Efficacy and tolerability of desensitization in the treatment of delayed drug hypersensitivities to anti-tuberculosis medications. ( Ban, GY; Jeong, YJ; Kim, SH; Lee, SH; Park, HS; Shin, SS; Shin, YS; Ye, YM, 2019) |
"A 64-year-old man without a history of drug allergy developed fever and severe headache." | 1.42 | [A case of tuberculous meningitis complicated with multiple drug hypersensitivity to antituberculosis agents]. ( Arai, M, 2015) |
"Rifampin has been reported to cause acute pancreatitis in up to 2." | 1.30 | Pancreatic insufficiency due to antituberculous therapy. ( Cohen, LB; Knowles, SR; Liu, BA; Shear, NH; Werb, MR, 1997) |
Research
Studies (39)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (53.85) | 18.7374 |
1990's | 9 (23.08) | 18.2507 |
2000's | 4 (10.26) | 29.6817 |
2010's | 5 (12.82) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Nadri, G | 1 |
Taneja, S | 1 |
Singh, V | 1 |
Mittal, P | 1 |
Ban, GY | 1 |
Jeong, YJ | 1 |
Lee, SH | 1 |
Shin, SS | 1 |
Shin, YS | 1 |
Park, HS | 1 |
Kim, SH | 1 |
Ye, YM | 1 |
Arai, M | 1 |
Aniked, S | 1 |
Bakouh, O | 1 |
Bourkadi, JE | 1 |
Kuwabara, K | 1 |
Ribi, C | 1 |
Hauser, C | 1 |
CHAVES, AD | 1 |
TANI, P | 1 |
POPPIUS, H | 1 |
GIUNIO, N | 1 |
Story, RE | 1 |
Ditto, AM | 1 |
Marra, F | 1 |
Cox, VC | 1 |
FitzGerald, JM | 1 |
Moadebi, S | 1 |
Elwood, RK | 1 |
Carrasco, E | 1 |
Zierski, M | 2 |
Bek, E | 1 |
Okwera, A | 1 |
Whalen, C | 1 |
Byekwaso, F | 1 |
Vjecha, M | 1 |
Johnson, J | 1 |
Huebner, R | 1 |
Mugerwa, R | 1 |
Ellner, J | 1 |
Urban, T | 1 |
Maquarre, E | 1 |
Housset, C | 1 |
Chouaid, C | 1 |
Devin, E | 1 |
Lebeau, B | 1 |
McKeon, J | 1 |
Patel, AM | 1 |
Corbella, X | 1 |
Vadillo, M | 1 |
Cabellos, C | 1 |
Fernandez-Viladrich, P | 1 |
Rufi, G | 1 |
Luo, C | 1 |
Chintu, C | 1 |
Bhat, G | 1 |
Raviglione, M | 1 |
Diwan, V | 1 |
DuPont, HL | 1 |
Zumla, A | 1 |
Shorr, AF | 1 |
Trotta, RF | 1 |
Liu, BA | 1 |
Knowles, SR | 1 |
Cohen, LB | 1 |
Werb, MR | 1 |
Shear, NH | 1 |
Beji, M | 1 |
Louzir, B | 1 |
Ben Rhomdane, N | 1 |
Zouari, M | 1 |
Mtimet, B | 1 |
Daghfous, J | 1 |
Martínez, E | 1 |
Collazos, J | 1 |
Mayo, J | 1 |
Maurya, V | 1 |
Panjabi, C | 1 |
Shah, A | 1 |
Newton, RW | 1 |
Rossouw, JE | 1 |
Saunders, SJ | 1 |
Sifontes, JE | 1 |
Holdiness, MR | 1 |
Nariman, S | 1 |
van Dijke, CP | 1 |
Mudde, AH | 1 |
Wilson, TM | 1 |
Mühlberger, F | 1 |
Lester, W | 1 |
Burgher, LW | 1 |
Kass, I | 1 |
Wolinsky, E | 1 |
Pregowski, W | 1 |
Stańczuk-Holub, A | 1 |
Petera, V | 1 |
Klapálek, D | 1 |
Paichl, P | 1 |
Pecený, A | 1 |
Reviews
2 reviews available for pyrazinamide and Drug Hypersensitivity
Article | Year |
---|---|
Adverse cutaneous reactions to antituberculosis drugs.
Topics: Acne Vulgaris; Adult; Amikacin; Antitubercular Agents; Drug Hypersensitivity; Ethambutol; Ethionamid | 1985 |
Adverse reactions to drugs used in the treatment of tuberculosis.
Topics: Antitubercular Agents; Drug Hypersensitivity; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomyci | 1988 |
Trials
3 trials available for pyrazinamide and Drug Hypersensitivity
Other Studies
34 other studies available for pyrazinamide and Drug Hypersensitivity
Article | Year |
---|---|
Anaphylaxis to rifampicin and pyrazinamide in a child with tuberculous meningitis: A case report.
Topics: Anaphylaxis; Antitubercular Agents; Child; Drug Hypersensitivity; Humans; Male; Pyrazinamide; Rifamp | 2017 |
Efficacy and tolerability of desensitization in the treatment of delayed drug hypersensitivities to anti-tuberculosis medications.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Desensitization, Immunologic; Drug Hypersensi | 2019 |
[A case of tuberculous meningitis complicated with multiple drug hypersensitivity to antituberculosis agents].
Topics: Antitubercular Agents; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Ethionamide; Hu | 2015 |
[The interest of addiction to first line anti-TB drugs].
Topics: Antitubercular Agents; Drug Eruptions; Drug Hypersensitivity; Ethambutol; Female; Humans; Isoniazid; | 2014 |
[Anti-tuberculosis chemotherapy and management of adverse reactions].
Topics: Aged, 80 and over; Antitubercular Agents; Child; Drug Administration Schedule; Drug Hypersensitivity | 2011 |
Adverse reactions to pyrazinamide.
Topics: Adult; Antitubercular Agents; Drug Eruptions; Drug Hypersensitivity; Exanthema; Female; Humans; Pyra | 2002 |
DRUG THERAPY FOR TUBERCULOUS PATIENTS OUTSIDE THE HOSPITAL.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Hypersensitivity; Drug Resistance; Drug | 1963 |
SIDE EFFECTS OF AN ANTITUBERCULOUS FIVE-DRUG REGIMEN: ETHIONAMIDE, CYCLOSERINE, PYRAZINAMIDE, VIOMYCIN AND ISONIAZID.
Topics: Amyloidosis; Antitubercular Agents; Cycloserine; Deafness; Drug Hypersensitivity; Duodenal Ulcer; Et | 1963 |
CHEMOTHERAPY OF PREVIOUSLY TREATED PATIENTS WITH PULMONARY TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Hypersensitivity; Drug Resistance; Drug | 1964 |
A 32-year-old man with tuberculosis, fever, and rash.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Hypersensitivity; Ethambutol; Exanthema; | 2004 |
Successful treatment of multidrug-resistant tuberculosis following drug-induced hepatic necrosis requiring liver transplant.
Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ciprofl | 2004 |
[Adverse reactions to short-course anti-tuberculous therapy (author's transl)].
Topics: Antitubercular Agents; Drug Hypersensitivity; Drug Tolerance; Humans; Isoniazid; Pyrazinamide; Rifam | 1981 |
[Side effects of various combinations of rifampin and isoniazid with ethambutol or streptomycin and pyrazinamide in short-term chemotherapy of newly-detected pulmonary tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Hypersensitivity; | 1980 |
[Allopurinol hypersensitivity. A possible cause of hepatitis and mucocutaneous eruptions in a patient undergoing antitubercular treatment].
Topics: Adult; Allopurinol; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; D | 1995 |
Antituberculous therapy and acute liver failure.
Topics: Adult; Antitubercular Agents; Drug Hypersensitivity; Female; Humans; Isoniazid; Liver Failure, Acute | 1995 |
Hypersensitivity hepatitis due to pyrazinamide.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Hypers | 1995 |
Human immunodeficiency virus type-1 infection in Zambian children with tuberculosis: changing seroprevalence and evaluation of a thioacetazone-free regimen.
Topics: Adolescent; Child; Child, Preschool; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV I | 1994 |
PZA hypersensitivity.
Topics: Antitubercular Agents; Drug Hypersensitivity; Humans; Male; Middle Aged; Pyrazinamide | 1996 |
Pancreatic insufficiency due to antituberculous therapy.
Topics: Antitubercular Agents; Chronic Disease; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol | 1997 |
[Thrombocytopenia following a re-introduction of rifampicin in a daily treatment. Apropos of a case].
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; D | 1995 |
Shock and cerebral infarct after rifampin re-exposure in a patient infected with human immunodeficiency virus.
Topics: Adult; Anaphylaxis; Antibiotics, Antitubercular; Antitubercular Agents; Cerebral Infarction; Drug Hy | 1998 |
Pyrazinamide induced photoallergy.
Topics: Adult; Antitubercular Agents; Dermatitis, Photoallergic; Drug Hypersensitivity; Female; Humans; Pyra | 2001 |
Side effects of drugs used to treat tuberculosis.
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Capreomycin; Chemical and Drug Induced Liver I | 1975 |
Hepatic complications of antituberculous therapy.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensi | 1975 |
Editorial: Rifampin in tuberculous meningitis.
Topics: Child; Child, Preschool; Drug Hypersensitivity; Drug Interactions; Drug Therapy, Combination; Humans | 1975 |
[Drug-induced fever?].
Topics: Aged; Drug Hypersensitivity; Fever; Humans; Male; Pyrazinamide; Skin Tests; Tuberculosis, Ocular | 1986 |
Clinical experience with ethambutol.
Topics: Aminosalicylic Acids; Blood Chemical Analysis; Capreomycin; Drug Combinations; Drug Hypersensitivity | 1970 |
[Allergy to antitubercular agents; with special reference to new drugs].
Topics: Adult; Aged; Agranulocytosis; Anaphylaxis; Antitubercular Agents; Capreomycin; Cycloserine; Drug Hyp | 1973 |
Treatment of drug-resistant tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Dr | 1971 |
Treatment of tuberculosis today in Nebraska.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Hypersensitivity; Ethambutol; Ethiona | 1973 |
New antituberculosis drugs and concepts of prophylaxis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Arthritis; Chemical and Drug Induced Liver Injury; Chil | 1974 |
[Treatment with pyrazinamide given in increased doses twice a week in combination with other drugs].
Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Drug Hypersensitivity; Drug Synergism; Drug Tol | 1973 |
The use of second line drugs in patients with drug resistance to standard tuberculostatics.
Topics: Ambulatory Care; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Hypersensitivity; Dr | 1968 |
[On the problem of chronic liver damage following drug therapy of tuberculosis].
Topics: Adult; Aminosalicylic Acids; Antitubercular Agents; Biopsy; Chemical and Drug Induced Liver Injury; | 1965 |