pyrazinamide has been researched along with Discitis in 3 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Discitis: Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No other case of spondylodiscitis caused by a mycobacterial coinfection pathogen has been reported so far." | 1.33 | [Cervical spondylodiscitis: one pathogen may hide another]. ( Ader, F; Bernard, L; Carlier, R; Perronne, C; Salomon, J; Toubiana, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rafailidis, PI | 1 |
| Avramopoulos, I | 1 |
| Sapkas, G | 1 |
| Falagas, ME | 1 |
| Toubiana, J | 1 |
| Salomon, J | 1 |
| Ader, F | 1 |
| Perronne, C | 1 |
| Carlier, R | 1 |
| Bernard, L | 1 |
| Ribeiro, MA | 1 |
| Barouni, AS | 1 |
| Augusto, CJ | 1 |
| Augusto, MV | 1 |
| Lopes, MT | 1 |
| Salas, CE | 1 |
3 other studies available for pyrazinamide and Discitis
| Article | Year |
|---|---|
Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates.
Topics: Anti-Bacterial Agents; Biopsy, Fine-Needle; Bone Transplantation; Cycloserine; Discitis; Drug Therap | 2006 |
[Cervical spondylodiscitis: one pathogen may hide another].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Cervical Vertebrae; Cholecystitis; Disc | 2006 |
PCR identification of Mycobacterium tuberculosis complex in a clinical sample from a patient with symptoms of tuberculous spondylodiscitis.
Topics: Adult; Antitubercular Agents; Biopsy; Discitis; Drug Therapy, Combination; Humans; Isoniazid; Male; | 2007 |