pyrazinamide has been researched along with Disbacteriosis in 3 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To address this issue, we utilized a murine model of antibiotic-induced dysbiosis to assay the bioavailability of rifampicin, moxifloxacin, pyrazinamide, and isoniazid in mouse plasma over a period of 12 h following individual oral administration." | 1.91 | The Dysbiosis Triggered by First-Line Tuberculosis Antibiotics Fails to Reduce Their Bioavailability. ( Dartois, V; Mittereder, LR; Namasivayam, S; Oland, S; Sher, A; Wang, H; Zimmerman, M, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Namasivayam, S | 2 |
| Zimmerman, M | 1 |
| Oland, S | 1 |
| Wang, H | 1 |
| Mittereder, LR | 2 |
| Dartois, V | 1 |
| Sher, A | 2 |
| Maiga, M | 1 |
| Yuan, W | 1 |
| Thovarai, V | 1 |
| Costa, DL | 1 |
| Wipperman, MF | 1 |
| Glickman, MS | 1 |
| Dzutsev, A | 1 |
| Trinchieri, G | 1 |
| Khan, N | 1 |
| Mendonca, L | 1 |
| Dhariwal, A | 1 |
| Fontes, G | 1 |
| Menzies, D | 1 |
| Xia, J | 1 |
| Divangahi, M | 1 |
| King, IL | 1 |
3 other studies available for pyrazinamide and Disbacteriosis
| Article | Year |
|---|---|
The Dysbiosis Triggered by First-Line Tuberculosis Antibiotics Fails to Reduce Their Bioavailability.
Topics: Animals; Antitubercular Agents; Biological Availability; Dysbiosis; Humans; Isoniazid; Mice; Moxiflo | 2023 |
Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy.
Topics: Animals; Antitubercular Agents; Clostridiales; Drug Combinations; Dysbiosis; Gastrointestinal Microb | 2017 |
Intestinal dysbiosis compromises alveolar macrophage immunity to Mycobacterium tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug-Related Side Effects and Adverse | 2019 |